in A Dictionary of Biomedicine
January 2010; p ublished online January 2010 .
Reference Entry. Subjects: Clinical Medicine. 45 words.
A method for identifying individual chromosomes on metaphase spreads by staining with *Giemsa after a brief trypsin treatment. The pattern of Giemsa banding is different from the banding...
in Medical Mycology
January 2002; p ublished online January 2002 .
Journal Article. Subjects: Mycology and Fungi; Infectious Diseases; Medical Toxicology; Veterinary Medicine; Environmental Science. 0 words.
We have previously demonstrated the antifungal activity of the weak bases chloroquine and quinacrine against Cryptococcus neoformans. Quinacrine, being fluorescent, was seen to be...
in The Journal of Medicine and Philosophy: A Forum for Bioethics and Philosophy of Medicine
January 2000; p ublished online January 2000 .
Journal Article. Subjects: Philosophy; Medical Ethics; Bioethics; Public Policy. 0 words.
Over the past two years, much has been made by some governments and the media about the possible callous and racist distribution of Quinacrine by two Americans to sterilize women in the...
in Clinical Infectious Diseases
July 2001; p ublished online July 2001 .
Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 5554 words.
Giardia lamblia is one of the most common parasitic infections. Although standard treatments are usually curative, some immunocompromised patients, including patients with...
in Nucleic Acids Symposium Series
October 2000; p ublished online October 2000 .
Journal Article. Subjects: Chemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 0 words.
Tetra-acridinyl peptide 2 was synthesized from Fmoc-Lys(Boc)-OH and Fmoc-Lys(Acr)-OH (1) with the peptide synthesizer. The CD measurement suggested that 2 forms a special organized...
Overview page. Subjects: Genetics and Genomics.
Quinacrine and Giemsa-stained human metaphase chromosomes show characteristic banding patterns, and standard methods have been adopted to designate the specific patterns displayed by each...
Reduction of membrane-bound ATPase activity in a Lactobacillus helveticus strain with slower growth at low pH
in FEMS Microbiology Letters
May 1996; p ublished online January 2006 .
Journal Article. 0 words.
One acid-sensitive variant of Lactobacillus helveticus, designated L. helveticus CPN4, was isolated from L. helveticus CP790 using neomycin...
in FEMS Yeast Research
January 2004; p ublished online January 2006 .
Journal Article. 3445 words.
In rich media proaminopeptidase I is targeted to the vacuole via the Cvt pathway and during starvation via autophagy. We here identify Atg23...
Chloroquine analogues in drug discovery: new directions of uses, mechanisms of actions and toxic manifestations from malaria to multifarious diseases
in Journal of Antimicrobial Chemotherapy
June 2015; p ublished online February 2015 .
Journal Article. Subjects: Medical Oncology; Critical Care. 8506 words.
Antimalarial drugs (e.g. chloroquine and its close structural analogues) were developed primarily to treat malaria; however, they are beneficial for many dermatological, immunological,...
in Human Reproduction
April 1996 .
Journal Article. Subjects: Reproductive Medicine. 0 words.
This study was designed to compare three different fluorescent probes to assay the acrosome reaction in human spermatozoa: chlortetracycline (CTC), mannosylated bovine serum albumin (BSA)...
in Nucleic Acids Research
November 1996; p ublished online November 1996 .
Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 3315 words.
By using electromobility shift assay (EMSA), we have identified a protein able to recognize the DNA only if it was previously reacted with minor groove binders. This protein binds with very...
Reversal of glibenclamide-induced coronary vasoconstriction by enhanced perfusion pulsatility: possible role for nitric oxide
in Cardiovascular Research
March 2000; p ublished online March 2000 .
Journal Article. Subjects: Cardiovascular Medicine. 5410 words.
Objectives: ATP-sensitive potassium channels (K+ ATP) prominently contribute to basal coronary tone; however, flow reserve...
Role of novel dye-linked dehydrogenases in the metabolism of polyethylene glycol by pure cultures of Sphingomonas sp. N6
in FEMS Microbiology Letters
July 1996; p ublished online January 2006 .
Journal Article. 0 words.
Polyethylene glycol and diglycolic acid dehydrogenase acitivities linked with 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide and...
Apoplastic oxidation of L-asparagine is involved in the control of the green algal endophyte Acrochaete operculata Correa & Nielsen by the red seaweed Chondrus crispus Stackhouse
in Journal of Experimental Botany
May 2005; p ublished online March 2005 .
Journal Article. Subjects: Plant Sciences and Forestry. 6304 words.
Gametophytes of the marine alga Chondrus crispus are more resistant than tetrasporophytes to infection by the filamentous endophytic alga Acrochaete operculata. It has been shown recently...
Chloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent
May 2010; p ublished online January 2010 .
Journal Article. Subjects: Medical Oncology; Neurology. 4754 words.
Glioblastoma (GBM) is a high-grade central nervous system malignancy and despite aggressive treatment strategies, GBM patients have a median survival time of just 1 year. Chloroquine (CQ),...
High-throughput measurement of the Tp53 response to anticancer drugs and random compounds using a stably integrated Tp53-responsive luciferase reporter
June 2002; p ublished online June 2002 .
Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 6933 words.
Human Tp53 is normally a short-lived protein. Tp53 protein is stabilized and levels are increased in response to a variety of cellular stresses, including those induced by genotoxic...