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secretory proteins x Carbohydrates x clear all

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The role of MRH domain-containing lectins in ERAD

Nobuko Hosokawa, Yukiko Kamiya and Koichi Kato.

in Glycobiology

June 2010; p ublished online January 2010 .

Journal Article. Subjects: Carbohydrates. 7134 words.

The endoplasmic reticulum (ER) quality control system ensures that newly synthesized proteins in the early secretory pathway are in the correct conformation. Polypeptides that have failed...

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Isolation, characterization, and extra-embryonic secretion of the Xenopus laevis embryonic epidermal lectin, XEEL

Saburo Nagata.

in Glycobiology

March 2005; p ublished online November 2004 .

Journal Article. Subjects: Carbohydrates. 7783 words.

The Xenopus laevis embryonic epidermal lectin (XEEL) is a novel member of a group of lectins including mammalian intelectins, frog oocyte cortical granule lectins, and plasma lectins in...

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Targeting of active rat α2,3-sialyltransferase to the yeast cell wall by the aid of the hsp 150Δ-carrier: toward synthesis of sLex-decorated L-selectin ligands

Pirkko Mattila, Vesa Joutsjoki, Eero Kaitera, Marja-Leena Majuri, Jaana Niittymäki, Nina Saris, Hannu Maaheimo, Ossi Renkonen, Risto Renkonen and Marja Makarow.

in Glycobiology

December 1996 .

Journal Article. Subjects: Carbohydrates. 0 words.

Interactions between selectins and their oligosaccharide-decorated ligands play a crucial role in the initiation of leukocyte extravasation. We have shown that synthetic multivalent sialyl...

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Galectin-3 in angiogenesis and metastasis

Tatsuyoshi Funasaka, Avraham Raz and Pratima Nangia-Makker.

in Glycobiology

October 2014; p ublished online August 2014 .

Journal Article. Subjects: Carbohydrates. 3538 words.

Galectin-3 is a member of the family of β-galactoside-binding lectins characterized by evolutionarily conserved sequences defined by structural similarities in their...

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Expression and characterization of rat UDP-N-acetylglucosamine: α-3-d-mannoside β-1,2-N-acetylglucosaminyltransferase I in Saccharomyces cerevisiae

Satoshi Yoshida, Misa Suzuki, Shigeyuki Yamano, Makoto Takeuchi, Hiroshi Ikenaga, Noriyuki Kioka, Hiroshi Sakai and Tohru Komano.

in Glycobiology

January 1999; p ublished online January 1999 .

Journal Article. Subjects: Carbohydrates. 4376 words.

The yeast Saccharomyces cerevisiae is a useful host for the production of heterologous proteins through the secretory pathway. However, because of the potential antigenicity of mannan-type...

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Teaching dolichol-linked oligosaccharides more tricks with alternatives to metabolic radiolabeling

Mark A Lehrman.

in Glycobiology

August 2007; p ublished online March 2007 .

Journal Article. Subjects: Carbohydrates. 6193 words.

The dolichol cycle involves synthesis of the lipid-linked oligosaccharide (LLO) Glc3Man9GlcNAc2-P-P-dolichol (G3M9Gn2-P-P-Dol), transfer of G3M9Gn2 to asparaginyl residues of nascent...

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N-Glycosylation of total cellular glycoproteins from the human ovarian carcinoma SKOV3 cell line and of recombinantly expressed human erythropoietin

Eda Machado, Sebastian Kandzia, Rita Carilho, Peter Altevogt, Harald S Conradt and Júlia Costa.

in Glycobiology

March 2011; p ublished online October 2010 .

Journal Article. Subjects: Carbohydrates. 6070 words.

Ovarian carcinoma is the leading cause of death from gynecological cancers in many Western countries. Aberrant glycosylation is an important aspect in malignant transformation and...

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Isotopic labeling with cellular O-glycome reporter/amplification (ICORA) for comparative O-glycomics of cultured cells

Matthew R Kudelka, Alison V Nairn, Mohammed Y Sardar, Xiaodong Sun, Elliot L Chaikof, Tongzhong Ju, Kelley W Moremen and Richard D Cummings.

in Glycobiology

April 2018; p ublished online January 2018 .

Journal Article. Subjects: Carbohydrates. 5690 words.


Mucin-type O-glycans decorate >80% of secretory and cell surface proteins and contribute to health and disease. However, dynamic alterations in the...

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Human sialic acid acetyl esterase: Towards a better understanding of a puzzling enzyme

Flavia Orizio, Eufemia Damiati, Edoardo Giacopuzzi, Giuliana Benaglia, Stefano Pianta, Roland Schauer, Reinhard Schwartz-Albiez, Giuseppe Borsani, Roberto Bresciani and Eugenio Monti.

in Glycobiology

September 2015; p ublished online May 2015 .

Journal Article. Subjects: Carbohydrates. 10021 words.

Sialic acid acetyl esterase (SIAE) removes acetyl moieties from the hydroxyl groups in position 9 and 4 of sialic acid. Recently, a dispute has been opened on its association to...

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Remodeling of sugar chain structures of human interferon-γ

Kazuhiro Fukuta, Reiko Abe, Tomoko Yokomatsu, Naoko Kono, Mineko Asanagi, Fumio Omae, Mari Toba Minowa, Makoto Takeuchi and Tadashi Makino.

in Glycobiology

April 2000; p ublished online April 2000 .

Journal Article. Subjects: Carbohydrates. 6212 words.

Natural human interferon (IFN)-γ has mainly biantennary complex-type sugar chains and scarcely has multiantennary structures. We attempted to remodel the sugar chain structures using IFN-γ...

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Identification of residues essential for carbohydrate recognition and cation dependence of the 46-kDa mannose 6-phosphate receptor

Guangjie Sun, Hongtao Zhao, B. Kalyanaraman and Nancy M. Dahms.

in Glycobiology

November 2005; p ublished online June 2005 .

Journal Article. Subjects: Carbohydrates. 9604 words.

The 46 kDa cation-dependent mannose 6-phosphate receptor (CD-MPR) plays an essential role in the biogenesis of lysosomes by diverting newly synthesized mannose 6-phosphate...

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Galectin-3 and soluble fibrinogen act in concert to modulate neutrophil activation and survival: involvement of alternative MAPK pathways

Gabriela C. Fernández, Juan M. Ilarregui, Carolina J. Rubel, Marta A. Toscano, Sonia A. Gómez, Macarena Beigier Bompadre, Martín A. Isturiz, Gabriel A. Rabinovich and Marina S. Palermo.

in Glycobiology

May 2005; p ublished online December 2004 .

Journal Article. Subjects: Carbohydrates. 6503 words.

Galectin-3 (Gal-3), a member of a family of highly conserved carbohydrate-binding proteins, has recently emerged as a novel cellular modulator at inflammatory foci. Here we investigated the...

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Externalization and binding of galectin-1 on cell surface of K562 cells upon erythroid differentiation

Didier Lutomski, Magali Fouillit, Philippe Bourin, Daniel Mellottée, Nicole Denize, Michel Pontet, Dominique Bladier, Michel Caron and Raymonde Joubert-Caron.

in Glycobiology

October 1997; p ublished online October 1997 .

Journal Article. Subjects: Carbohydrates. 0 words.

Galectin 1 (GAL1) is a β-galactoside-binding lectin involved in cell cycle progression. GAL1 overexpression is associated with neoplastic transformation and loss of differentiation. The...

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Glycan gimmickry by parasitic helminths: A strategy for modulating the host immune response?

Irma van Die and Richard D Cummings.

in Glycobiology

January 2010; p ublished online September 2009 .

Journal Article. Subjects: Carbohydrates. 8260 words.

Parasitic helminths (worms) co-evolved with vertebrate immune systems to enable long-term survival of worms in infected hosts. Among their survival strategies, worms use their glycans...

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Abnormal surface expression of sialoglycans on B lymphocyte cell lines from patients with carbohydrate deficient glycoprotein syndrome I A (CDGS I A)

Markus Bergmann, Hans-Jürgen Gross, Fawzy Abdelatty, Peter Möller, Jaak Jaeken and Reinhard Schwartz-Albiez.

in Glycobiology

October 1998; p ublished online October 1998 .

Journal Article. Subjects: Carbohydrates. 7126 words.

The carbohydrate-deficient glycoprotein syndromes (CDGS) are genetic, multisystemic diseases characterized by deficiencies in the glycosylation of many secretory glycoproteins, lysosomal...

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Evidence for core 2 to core 1 O-glycan remodeling during the recycling of MUC1

Hanieh Razawi, Carol L Kinlough, Simon Staubach, Paul A Poland, Youssef Rbaibi, Ora A Weisz, Rebecca P Hughey and Franz-Georg Hanisch.

in Glycobiology

August 2013; p ublished online May 2013 .

Journal Article. Subjects: Carbohydrates. 6416 words.

The apical transmembrane glycoprotein MUC1 is endocytosed to recycle through the trans-Golgi network (TGN) or Golgi complex to the plasma membrane. We followed the hypothesis that not only...

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Glycosylation and proteolytic processing of 70 kDa C-terminal recombinant polypeptides of Plasmodium falciparum merozoite surface protein 1 expressed in mammalian cells

Shutong Yang, David Nikodem, Eugene A. Davidson and D.Channe Gowda.

in Glycobiology

December 1999; p ublished online December 1999 .

Journal Article. Subjects: Carbohydrates. 7099 words.

The cDNAs that encode the 70 kDa C-terminal portion of Plasmodium falciparum merozoite surface protein 1 (MSP-1), with or without an N-terminal signal peptide sequence and C-terminal...

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