Oxford Index Search Results

You are looking at 21-40 of 73 items for:

steric hindrance x clear all

Inhibition of Staphylococcal Enterotoxin A–Induced Superantigenic and Lethal Activities by a Monoclonal Antibody to Toxic Shock Syndrome Toxin-1

Winnie W. S. Kum and Anthony W. Chow.

in The Journal of Infectious Diseases

June 2001; p ublished online June 2001 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 6451 words.

Staphylococcal toxic shock syndrome is caused by a family of related superantigens that includes toxic shock syndrome toxin–1 (TSST-1) and staphylococcal enterotoxins (SEs) A, B, and C. The...

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Molecular basis for the enantioselectivity of HIV-1 reverse transcriptase: Role of the 3′-hydroxyl group of the L-(β)-ribose in chiral discrimination between D- and L-enantiomers of deoxy- and dideoxy-nucleoside triphosphate analogs

Giovanni Maga, Silvio Spadari, Mario Amacker, Ulrich Hübscher, Gilles Gosselin, Jean-Luis Imbach, Christophe Mathé, Abdesslem Faraj and Jean-Pierre Sommadossi.

in Nucleic Acids Research

February 1999; p ublished online February 1999 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 3918 words.

In order to identify the basis for the relaxed enantioselectivity of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) and to evaluate possible cross-resistance...

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Glycosylation of the overlapping sequons in yeast external invertase: effect of amino acid variation on site selectivity in vivo and in vitro

Anthony Reddy, Barbara S. Gibbs, Yun-Li Liu, James K. Coward, Li-Ming Changchien and Frank Maley.

in Glycobiology

June 1999; p ublished online June 1999 .

Journal Article. Subjects: Carbohydrates. 6832 words.

Yeast invertase contains 14 sequons, all of which are glycosylated to varying degrees except for sequon 5 which is marginally glycosylated, if at all. This sequon overlaps with sequon 4 in...

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Intermolecular ‘cross-torque’: the N4 -cytosine propargyl residue is rotated to the ‘CH’-edge as a result of Watson–Crick interaction

Olwen Domingo, Isabell Hellmuth, Andres Jäschke, Christoph Kreutz and Mark Helm.

in Nucleic Acids Research

June 2015; p ublished online April 2015 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 5770 words.

Propargyl groups are attractive functional groups for labeling purposes, as they allow CuAAC-mediated bioconjugation. Their size minimally exceeds that of a methyl group, the latter being...

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Three-dimensionally designed protein-responsive RNA devices for cell signaling regulation

Shunnichi Kashida, Tan Inoue and Hirohide Saito.

in Nucleic Acids Research

October 2012; p ublished online July 2012 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 5440 words.

The three-dimensional (3D) structures of many biomacromolecules have been solved to reveal the functions of these molecules. However, these 3D structures have rarely been applied to...

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Substrate Recognition and Activation Mechanism of D-Amino Acid Chridase: A Study Using Substrate Analogs

Yasuzo Nishina, Kyosuke Sato, Retsu Miura and Kiyoshi Shiga.

in The Journal of Biochemistry

August 2000; p ublished online August 2000 .

Journal Article. Subjects: Biochemistry. 0 words.

We investigated the mechanism of recognition and activation of substrate by D-amino acid oxidase (DAO) by thennodynamical and spectrophotometric methods using zwitte-rionic ligands [N-methy...

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NMR evaluation of ammonium ion movement within a unimolecular G-quadruplex in solution

Peter Podbevšek, Nicholas V. Hud and Janez Plavec.

in Nucleic Acids Research

April 2007; p ublished online April 2007 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 7309 words.

d[G4(T4G4)3] has been folded into a unimolecular G-quadruplex in the presence of 15[math] ions. NMR spectroscopy confirmed that its topology is the same as the solution state structure...

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Amyloid-β peptide (1–42) aggregation induced by copper ions under acidic conditions

Yannan Bin, Xia Li, Yonghui He, Shu Chen and Juan Xiang.

in Acta Biochimica et Biophysica Sinica

July 2013; p ublished online June 2013 .

Journal Article. Subjects: Biochemistry. 4478 words.

It is well known that the aggregation of amyloid-β peptide (Aβ) induced by Cu2+ is related to incubation time, solution pH, and temperature. In this work, the aggregation of Aβ1–42 in the...

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Reduction of the Suppressive Effects of Gurmarin on Sweet Taste Responses by Addition of β-Cyclodextrin

Yuzo Ninomiya, Masashi Inoue and Toshiaki Imoto.

in Chemical Senses

June 1998; p ublished online June 1998 .

Journal Article. Subjects: Molecular and Cell Biology. 0 words.

Cyclodextrins (CDs) have the remarkable ability to form inclusion complexes with a wide variety of guest molecules. In the present study, possible influences of CDs on gurmarin inhibition...

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Synoptic determination of living/dead and active/dormant bacterial fractions in marine sediments

E. Manini and R. Danovaro.

in FEMS Microbiology Ecology

March 2006; p ublished online January 2006 .

Journal Article. 4487 words.

Abstract

The most widely used methods for the estimation of the living/dead fractions of bacterial cells involve specific stains that are able to reveal...

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Direct binding of polysialic acid to a brain-derived neurotrophic factor depends on the degree of polymerization

Yukihiro Kanato, Ken Kitajima and Chihiro Sato.

in Glycobiology

December 2008; p ublished online September 2008 .

Journal Article. Subjects: Carbohydrates. 7648 words.

Polysialic acid (polySia) is the homopolymer of sialic acid and negatively regulates neuronal cell–cell and cell–extracellular matrix interactions through steric and repulsive hindrance due...

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Antibodies to human ZP3 induce reversible contraception in transgenic mice with `humanized' zonae pellucidae

Stephen Greenhouse, Philip E. Castle and Jurrien Dean.

in Human Reproduction

March 1999; p ublished online March 1999 .

Journal Article. Subjects: Reproductive Medicine. 6589 words.

The initial spermatozoon–egg interaction of mammalian fertilization is mediated by the zona pellucida, an extracellular matrix composed of three glycoproteins (ZP1, ZP2, ZP3). These proteins...

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Comparison of tetracycline and tigecycline binding to ribosomes mapped by dimethylsulphate and drug-directed Fe2+ cleavage of 16S rRNA

Gesine Bauer, Christian Berens, Steven J. Projan and Wolfgang Hillen.

in Journal of Antimicrobial Chemotherapy

April 2004; p ublished online April 2004 .

Journal Article. Subjects: Medical Oncology; Critical Care. 5050 words.

Objectives: The new antibiotic tigecycline (9-t-butylglycylamido-minocycline; GAR-936) overcomes most of the known tetracycline resistance mechanisms. Here we analyse its mode...

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Evaluation of 3-deaza-adenosine analogues as ligands for adenosine kinase and inhibitors of Mycobacterium tuberculosis growth

Mary C. Long, Paula W. Allan, Mei-Zhen Luo, Mao-Chin Liu, Alan C. Sartorelli and William B. Parker.

in Journal of Antimicrobial Chemotherapy

January 2007; p ublished online November 2006 .

Journal Article. Subjects: Medical Oncology; Critical Care. 2300 words.

Objectives: Analyse a series of halogenated 3-deaza-adenosine analogues for efficacy against Mycobacterium tuberculosis H37Ra and determine if adenosine (Ado) kinase plays a...

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Quantitative Structure—Retention Relationships for Polychlorinated Biphenyls and Chlorobenzenes on Selected Normal-Phase Liquid Chromatographic Stationary Phases

Eva Grimvall, Anders Colmsjö, Kent Wrangskog, Conny Östman and Maria Eriksson.

in Journal of Chromatographic Science

February 1997; p ublished online February 1997 .

Journal Article. Subjects: Chemistry. 0 words.

Linear regression between capacity factors and solute properties is performed to evaluate quantitative structure—retention relationships. A general increase in retention on porous graphitic...

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The Retention of Some Open-Chain Diamines on a Strong Cation-Exchange Resin in Ion Chromatography

Francesco Crea, Alessandro De Robertis and Ottavia Giuffrè.

in Journal of Chromatographic Science

March 2004; p ublished online March 2004 .

Journal Article. Subjects: Chemistry. 0 words.

This work reports the results of a study of the influence of the structure of some open-chain diamines on their retention in high-performance ion chromatography (HPIC). We examine a set of...

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In vitro interactions between amphotericin B and hydrocortisone: potential implications for intrathecal therapy

Greg Hodge, Stuart H. Cohen and George R. Thompson.

in Medical Mycology

September 2015; p ublished online July 2015 .

Journal Article. Subjects: Infectious Diseases; Medical Toxicology; Environmental Science; Mycology and Fungi; Veterinary Medicine. 2315 words.

Fungal meningitis remains a severe and often lethal infection requiring aggressive antifungal therapy and in refractory cases the use of intrathecal amphotericin B (AmB). Administration of...

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DNA microarrays on a dendron-modified surface improve significantly the detection of single nucleotide variations in the p53 gene

Soon Jin Oh, Jimin Ju, Byung Chul Kim, Eunsil Ko, Bong Jin Hong, Jae-Gahb Park, Joon Won Park and Kwan Yong Choi.

in Nucleic Acids Research

June 2005; p ublished online June 2005 .

Journal Article. Subjects: Research Methods in Life Sciences. 4467 words.

Selectivity and sensitivity in the detection of single nucleotide polymorphisms (SNPs) are among most important attributes to determine the performance of DNA microarrays. We previously...

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Fluorescence protection assay: a novel homogeneous assay platform toward development of aptamer sensors for protein detection

Hong-Qi Wang, Zhan Wu, Li-Juan Tang, Ru-Qin Yu and Jian-Hui Jiang.

in Nucleic Acids Research

October 2011; p ublished online July 2011 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 3527 words.

Development of novel aptamer sensor strategies for rapid and selective assays of protein biomarkers plays crucial roles in proteomics and clinical diagnostics. Herein, we have developed a...

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The C-terminal region of Escherichia coli UvrC contributes to the flexibility of the UvrABC nucleotide excision repair system

Esther E. A. Verhoeven, Marian van Kesteren, John J. Turner, Gijs A. van der Marel, Jacques H. van Boom, Geri F. Moolenaar and Nora Goosen.

in Nucleic Acids Research

June 2002; p ublished online June 2002 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 6949 words.

Nucleotide excision repair in Escherichia coli involves formation of the UvrB–DNA complex and subsequent DNA incisions on either site of the damage by UvrC. In this paper, we studied the...

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