Oxford Index Search Results

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Drug discovery for human immunodeficiency virus infection: conquests and hurdles

Richard J. Whitley.

in Journal of Antimicrobial Chemotherapy

May 1996; p ublished online May 1996 .

Journal Article. Subjects: Medical Oncology; Critical Care. 0 words.

Drug development for the treatment of human immunodeficiency virus infection arena has been characterised by both successes and failures. The nucleoside reverse transcriptase inhibitors...

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Activity of penciclovir in antiviral assays against herpes simplex virus

Teresa H. Bacon, Barbara A. Howard, Lindsay C. Spender and Malcolm R. Boyd.

in Journal of Antimicrobial Chemotherapy

February 1996; p ublished online February 1996 .

Journal Article. Subjects: Medical Oncology; Critical Care. 0 words.

The effect of penciclovir and acyclovir on the replication of herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) strains was determined in MRC-5 cells infected with 0.01 pfu/cell and...

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Current Perspectives on the Molecular Pathogenesis of Virus-Induced Cancers in Human Immunodeficiency Virus Infection and Acquired Immunodeficiency Syndrome

Elliott Kieff.

in JNCI Monographs

April 1998; p ublished online April 1998 .

Journal Article. Subjects: Medical Oncology. 7261 words.

A distinct group of cancers particularly threaten human immunodeficiency virus (HIV)-infected people. Most HIV/acquired immunodeficiency syndrome (AIDS)-associated cancers have a ...

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Hepatitis B virus: old, new and future approaches to antiviral treatment

Peter Karayiannis.

in Journal of Antimicrobial Chemotherapy

April 2003; p ublished online April 2003 .

Journal Article. Subjects: Medical Oncology; Critical Care. 20580 words.

Patients chronically infected with hepatitis B virus (HBV) run the risk of developing cirrhosis and hepatocellular carcinoma in later life. Antiviral treatment offers the only means of...

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The many challenges of facial herpes simplex virus infection

Jørgen Esmann.

in Journal of Antimicrobial Chemotherapy

February 2001; p ublished online February 2001 .

Journal Article. Subjects: Medical Oncology; Critical Care. 0 words.

Infection with herpes simplex virus type 1 (HSV-1) is common throughout the world, with many cases leading to symptomatic facial herpes. Following primary infection, HSV-1 establishes...

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Mutations conferring zanamivir resistance in human influenza virus N2 neuraminidases compromise virus fitness and are not stably maintained in vitro

Thomas Zürcher, Phillip J. Yates, Janet Daly, Anjali Sahasrabudhe, Matthew Walters, Laura Dash, Margaret Tisdale and Jennifer L. McKimm-Breschkin.

in Journal of Antimicrobial Chemotherapy

October 2006; p ublished online August 2006 .

Journal Article. Subjects: Medical Oncology; Critical Care. 7105 words.

Background: Viruses resistant to zanamivir have been generated in vitro, but no resistant virus has yet been isolated from a zanamivir-treated immunocompetent patient. In...

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Genotypic resistance to lamivudine among hepatitis B virus isolates in Mexico

Cosme Alvarado-Esquivel, Manuela de la Ascensión Carrera-Gracia, Carlos Jesús Conde-González, Luis Juárez-Figueroa, Lilia Ruiz-Maya, Sergio Aguilar-Benavides, Alejandro Torres-Valenzuela and Erwin Sablon.

in Journal of Antimicrobial Chemotherapy

February 2006; p ublished online December 2005 .

Journal Article. Subjects: Medical Oncology; Critical Care. 2154 words.

Background: Drug resistance of hepatitis B virus (HBV) is an increasing clinical problem. Resistance to lamivudine in HBV isolates in Mexico has been poorly explored.

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IMMU-73. GLIOMA IN SITU VACCINATION WITH COWPEA MOSAIC VIRUS NANOPARTICLES

Amber Kerstetter-Fogle, Sourabh Shukla, Veronique Beiss, Peggy Harris, Andrew Sloan and Nicole Steinmetz.

in Neuro-Oncology

November 2018; p ublished online November 2018 .

Journal Article. Subjects: Medical Oncology; Neurology. 0 words.

Abstract

Glioblastoma multiforme is the most malignant brain cancer affecting adults. Despite recent advancements, the current prognosis is dismal with median...

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IMMU-47. HARNESSING ZIKA VIRUS (ZIKV) ONCOLYTIC ACTIVITY IN BRAIN TUMORS

Arijita Jash, Jennifer Govero, Pei-Yong Shi, Jeremy Rich, Michael S Diamond and Milan G Chheda.

in Neuro-Oncology

November 2018; p ublished online November 2018 .

Journal Article. Subjects: Medical Oncology; Neurology. 0 words.

Abstract

Glioblastoma (GBM) is a highly lethal immunosuppressive brain cancer that contains glioblastoma stem-like cells (GSCs). GSCs are at least partly...

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Erythrocyte-mediated delivery of a new homodinucleotide active against human immunodeficiency virus and herpes simplex virus

Luigia Rossi, Sonja Serafini, Loredana Cappellacci, Emanuela Balestra, Giorgio Brandi, Giuditta F. Schiavano, Palmarisa Franchetti, Mario Grifantini, Carlo-Federico Perno and Mauro Magnani.

in Journal of Antimicrobial Chemotherapy

June 2001; p ublished online June 2001 .

Journal Article. Subjects: Medical Oncology; Critical Care. 6024 words.

Monocyte-derived macrophages (MDMs) play a central role in the pathogenesis of infection by human immunodeficiency virus (HIV-1) and represent one of the main reservoirs of the virus in the...

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Inhibition of respiratory syncytial virus by RhoA-derived peptides: implications for the development of improved antiviral agents targeting heparin-binding viruses

Philip J. Budge and Barney S. Graham.

in Journal of Antimicrobial Chemotherapy

August 2004; p ublished online August 2004 .

Journal Article. Subjects: Medical Oncology; Critical Care. 3135 words.

The respiratory syncytial virus (RSV) fusion glycoprotein (F) can interact with the small intracellular GTPase RhoA, and peptides derived from RhoA inhibit RSV replication. These...

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EXTH-53. IN VIVO QUANTITATIVE ANALYSIS OF ONCOLYTIC VIRUS-TUMOR KINETICS

Hirotaka Ito, Hiroshi Nakashima, Eric McLaughlin and E Antonio Chiocca.

in Neuro-Oncology

November 2018; p ublished online November 2018 .

Journal Article. Subjects: Medical Oncology; Neurology. 0 words.

Abstract

Oncolytic virus (OV) immunotherapy is becoming a clinically feasible therapy for cancer, with one FDA-approved product and many more in the clinical...

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ET-40ONCOLYTIC VIRUS INDUCED HMGB1 SECRETION AND ITS IMPACT ON TUMOR ANGIOGENESIS

Kamaldeen Muili, Chelsea Bolyard, Cristina Jaime-Ramirez, Ji Young Yoo and Balveen Kaur.

in Neuro-Oncology

November 2014; p ublished online November 2014 .

Journal Article. Subjects: Medical Oncology; Neurology. 0 words.

Glioblastoma multiforme (GBM) is a difficult-to-treat, and the most aggressive of primary brain tumors. Survival is less than 2 years despite aggressive therapy. Oncolytic virus (OV)...

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Progression of liver fibrosis in patients coinfected with hepatitis C virus and human immunodeficiency virus undergoing antiretroviral therapy

Juan A. Pineda and Juan Macías.

in Journal of Antimicrobial Chemotherapy

April 2005; p ublished online April 2005 .

Journal Article. Subjects: Medical Oncology; Critical Care. 2381 words.

As the immunosuppression caused by human immunodeficiency virus (HIV) accelerates the progression of hepatitis C virus (HCV)-related liver fibrosis, the immune reconstitution associated with...

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ASP2151, a novel helicase–primase inhibitor, possesses antiviral activity against varicella–zoster virus and herpes simplex virus types 1 and 2

Koji Chono, Kiyomitsu Katsumata, Toru Kontani, Masayuki Kobayashi, Kenji Sudo, Tomoyuki Yokota, Kenji Konno, Yasuaki Shimizu and Hiroshi Suzuki.

in Journal of Antimicrobial Chemotherapy

August 2010; p ublished online June 2010 .

Journal Article. Subjects: Medical Oncology; Critical Care. 5914 words.

Objectives

To evaluate and describe the anti-herpesvirus effect of ASP2151, amenamevir, a novel non-nucleoside oxadiazolylphenyl-containing herpesvirus...

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Response to raltegravir-based salvage therapy in HIV-infected patients with hepatitis C virus or hepatitis B virus coinfection

Liliana Elena Weimer, Vincenzo Fragola, Marco Floridia, Giovanni Guaraldi, Nicoletta Ladisa, Daniela Francisci, Rita Bellagamba, Anna Degli Antoni, Giustino Parruti, Andrea Giacometti, Paolo Emilio Manconi, Angela Vivarelli, Gabriella D'Ettorre, Maria Stella Mura, Stefania Cicalini, Roberta Preziosi, Laura Sighinolfi, Gabriella Verucchi, Raffaella Libertone, Marcello Tavio, Loredana Sarmati and Raffaella Bucciardini.

in Journal of Antimicrobial Chemotherapy

January 2013; p ublished online September 2012 .

Journal Article. Subjects: Medical Oncology; Critical Care. 3191 words.

Objectives

To define the impact of coinfection with hepatitis B virus (HBV) or hepatitis C virus (HCV) on viroimmunological response to raltegravir-based...

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Putranjivain A from Euphorbia jolkini inhibits both virus entry and late stage replication of herpes simplex virus type 2 in vitro

Hua-Yew Cheng, Ta-Chen Lin, Chien-Min Yang, Kuo-Chih Wang, Liang-Tzung Lin and Chun-Ching Lin.

in Journal of Antimicrobial Chemotherapy

April 2004; p ublished online April 2004 .

Journal Article. Subjects: Medical Oncology; Critical Care. 5038 words.

Aims: To investigate the in vitro antiviral properties of putranjivain A, isolated from the whole plant of Euphorbia jolkini Bioss (Euphorbiaceae).

Methods...

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P17.58DETECTION OF HUMAN PAPILLOMA VIRUS DNA IN A SUBSET OF GLIOBLASTOMA SAMPLES

G. Gasparre, M. Vidone, M. Cricca, C. Savini, E. Trevisan, R. Soffietti, G. Faccani, M. Leone and I. Morra.

in Neuro-Oncology

September 2014; p ublished online September 2014 .

Journal Article. Subjects: Medical Oncology; Neurology. 0 words.

BACKGROUND: Glioblastoma Multiforme (GBM) is the most common malignant brain tumor in adults, but its aetiology remains unknown. Recent reports have demonstrated the presence of neurotropic...

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Association Between Hepatitis C Virus and Head and Neck Cancers

Parag Mahale, Erich M. Sturgis, David J. Tweardy, Ella J. Ariza-Heredia and Harrys A. Torres.

in JNCI: Journal of the National Cancer Institute

P ublished online April 2016 .

Journal Article. Subjects: Medical Oncology; Radiation Oncology; Surgical Oncology. 6557 words.

Background: Hepatitis C virus (HCV) infection is associated with hepatocellular carcinoma and non-Hodgkin’s lymphoma. In 2009, MD Anderson established the first US clinic for...

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Effect of Tumor Microenvironment Modulation on the Efficacy of Oncolytic Virus Therapy

Kazuhiko Kurozumi, Jayson Hardcastle, Roopa Thakur, Ming Yang, Gregory Christoforidis, Giulia Fulci, Fred H. Hochberg, Ralph Weissleder, William Carson, E. Antonio Chiocca and Balveen Kaur.

in JNCI: Journal of the National Cancer Institute

December 2007; p ublished online December 2007 .

Journal Article. Subjects: Medical Oncology. 11124 words.

Background

The tumor microenvironment is being increasingly recognized as an important determinant of tumor progression as well as of therapeutic response....

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