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Marsh x Anaesthetics x clear all

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Overview page. Subjects: Biological Sciences.

A more or less permanently wet area of mineral soil (as opposed to a peaty area), typically found around the edges of a lake or on an undrained river flood-plain. Colloquially, ‘marsh’ is...

See overview in Oxford Index

Total intravenous anaesthesia

JK Oosterhuis and AR Absalom.

in Landmark Papers in Anaesthesia

August 2013; p ublished online October 2013 .

Chapter. Subjects: Anaesthetics. 5693 words.

Chapter 4 covers total intravenous anaesthesia (TIVA), its modern popularity, the complexities of pharmacokinetics of drug infusions and the benefits of the use of computer simulations in...

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Pharmacokinetic models for propofol—defining and illuminating the devil in the detail

A. R. Absalom, V. Mani, T. De Smet and M. M. R. F. Struys.

in BJA: British Journal of Anaesthesia

July 2009; p ublished online June 2009 .

Journal Article. Subjects: Anaesthetics. 6596 words.

The recently introduced open-target-controlled infusion (TCI) systems can be programmed with any pharmacokinetic model, and allow either plasma- or effect-site targeting. With effect-site...

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Study of the time course of the clinical effect of propofol compared with the time course of the predicted effect-site concentration: performance of three pharmacokinetic–dynamic models

M. Coppens, J. G. M. Van Limmen, T. Schnider, B. Wyler, S. Bonte, F. Dewaele, M. M. R. F. Struys and H. E. M. Vereecke.

in BJA: British Journal of Anaesthesia

April 2010; p ublished online February 2010 .

Journal Article. Subjects: Anaesthetics. 3168 words.


In the ideal pharmacokinetic–dynamic (PK–PD) model for calculating the predicted effect-site concentration of propofol (CePROP), for any CePROP,...

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Precision and bias of target controlled propofol infusion for sedation

M. A. Frölich, D. M. Dennis, J. A. Shuster and R. J. Melker.

in BJA: British Journal of Anaesthesia

April 2005; p ublished online January 2005 .

Journal Article. Subjects: Anaesthetics. 2510 words.

Background. The purpose of this study is to test precision and systematic bias of a target controlled infusion (TCI) of propofol in human volunteers at two sedative...

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Target‐controlled infusion of propofol and remifentanil in cardiac anaesthesia: influence of age on predicted effect‐site concentrations

A. Ouattara, G. Boccara, S. Lemaire, U. Köckler, M. Landi, E. Vaissier, P. Léger and P. Coriat.

in BJA: British Journal of Anaesthesia

May 2003; p ublished online May 2003 .

Journal Article. Subjects: Anaesthetics. 3498 words.

Background. Propofol‐anaesthesia administrated via target‐controlled infusion (TCI) has been proposed for cardiac surgery. Age‐related changes in pharmacology explain why...

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Evaluation of the predictive performance of four pharmacokinetic models for propofol

J. B. Glen and F. Servin.

in BJA: British Journal of Anaesthesia

May 2009; p ublished online March 2009 .

Journal Article. Subjects: Anaesthetics. 3996 words.


This study has compared the predictive performance of four pharmacokinetic models, two of which are currently incorporated in commercial...

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