Oxford Index Search Results

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PCB x Genetics and Genomics x clear all

PCB

Overview page. Subjects: Computing.

(or

Abbrev. for printed circuit board. See printed circuit.

See overview in Oxford Index

PCBs do not induce DNA breakage in vitro in human lymphocytes

K. Belpaeme, K. Delbeke, L. Zhu and M.Kirsch Volders.

in Mutagenesis

July 1996 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Genetics and Genomics. 0 words.

Polychlorinated biphenyls (PCBs) are classified by IARC as non-mutagenic in vivo. However, despite almost 20 years of research, their mutagenicity in vitro is still debatable. In this work...

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Chromosome fragility in dairy cows exposed to dioxins and dioxin-like PCBs

G.P. Di Meo, A. Perucatti, V. Genualdo, A. Caputi-Jambrenghi, R. Rasero, C. Nebbia and L. Iannuzzi.

in Mutagenesis

March 2011; p ublished online October 2010 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Genetics and Genomics. 2551 words.

In this study, we compared cross-bred dairy cows in the Susa Valley (Piedmont, northern Italy), reared either near a high-temperature steel production plant (Farms A and B) or in an...

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Cytogenetic studies of PCB77 on brown trout (Salmo trutta fario) using the micronucleus test and the alkaline comet assay

K. Belpaeme, K. Delbeke, L. Zhu and M. Kirsch-Volders.

in Mutagenesis

September 1996 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Genetics and Genomics. 0 words.

Polychlorinated biphenyls (PCBs) are stable pollutants, which can be found in almost every compartment of terrestrial and aquatic ecosystems. They are very lipophilic and therefore have the...

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Induction of aberrant mitosis with PCBs: particular efficiency of 2,3,3′,4,4′-pentachlorobiphenyl and synergism with triphenyltin

Klaus Gjervig Jensen, Kate Wiberg, Eva Klasson-Wehler and Agneta Önfelt.

in Mutagenesis

January 2000; p ublished online January 2000 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Genetics and Genomics. 5443 words.

The polychlorinated biphenyls 2,2′,5,5′- and 3,3′,4,4′-tetrachlorobiphenyl, 2,3,3′,4,4′- and 3,3′,4,4′,5-pentachlorobiphenyl and 2,2′,4,4′,5,5′-hexachlorobiphenyl were tested for...

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Role of DNA methylation in altered gene expression patterns in adult zebrafish (Danio rerio) exposed to 3, 3’, 4, 4’, 5-pentachlorobiphenyl (PCB 126)

Neelakanteswar Aluru, Sibel I Karchner, Keegan S Krick, Wei Zhu and Jiang Liu.

Edited by Ramji Bhandari.

in Environmental Epigenetics

P ublished online April 2018 .

Journal Article. Subjects: Molecular Biology and Genetics; Biological Sciences; Developmental Biology; Evolutionary Biology; Genetics and Genomics. 8754 words.

Abstract

There is growing evidence that environmental toxicants can affect various physiological processes by altering DNA methylation patterns. However, very...

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Mutation frequency in the lacI gene of liver DNA from lambda/lacI transgenic mice following the interaction of PCBs with iron causing hepatic cancer and porphyria

Reginald Davies, Bruce Clothier and Andrew G. Smith.

in Mutagenesis

September 2000; p ublished online September 2000 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Genetics and Genomics. 3673 words.

The synergistic interaction of iron overload, Ahr genotype and exposure to a mixture of polychlorinated biphenyls (PCBs) (Aroclor 1254) in mice leads to hepatic porphyria, oxidative DNA...

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Reactive oxygen species from the uncoupling of human cytochrome P450 1B1 may contribute to the carcinogenicity of dioxin-like polychlorinated biphenyls

Richard M. Green, Nikolas J. Hodges, J. Kevin Chipman, Michael R. O'Donovan and Mark Graham.

in Mutagenesis

November 2008; p ublished online June 2008 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Genetics and Genomics. 5283 words.

Polychlorinated biphenyls (PCBs) are classified by the International Agency for Research on Cancer as probable human carcinogens. A subset of PCBs are described as ‘dioxin like’ because of...

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Low-dose persistent organic pollutants increased telomere length in peripheral leukocytes of healthy Koreans

Ji-Yeon Shin, Yi Young Choi, Hyo-Sung Jeon, Jun-Hyun Hwang, Sung-Ae Kim, Jung-Ho Kang, Yoon-Seok Chang, David R. Jacobs, Jae Yong Park and Duk-Hee Lee.

in Mutagenesis

September 2010; p ublished online July 2010 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Genetics and Genomics. 4067 words.

Although shortened telomeres have been found in many cancers, elongated telomere length has been observed as an early response after low-dose treatment with various chemical carcinogens in...

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In pancreatic ductal adenocarcinoma blood concentrations of some organochlorine compounds and coffee intake are independently associated with KRAS mutations

Miquel Porta, Tomàs López, José Pumarega, Manuel Jariod, Marta Crous-Bou, Esther Marco, Juli Rifà, Joan O. Grimalt, Núria Malats and Francisco X. Real.

in Mutagenesis

November 2009; p ublished online October 2009 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Genetics and Genomics. 6176 words.

While KRAS activation is a fundamental initiating event in the aetiopathogenesis of pancreatic ductal adenocarcinoma (PDA), environmental factors influencing the occurrence and persistence...

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N-Benzylimidazole for preparation of S9 fraction with multi-induction of metabolizing enzymes in short-term genotoxicity assays

Yukio Mori, Akihiro Koide, Kohji Fuwa and Yoshinori Kobayashi.

in Mutagenesis

November 2001; p ublished online November 2001 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Genetics and Genomics. 7049 words.

To evaluate the usefulness of N-benzylimidazole (BI) as an inducer with wide spectrum detection of precarcinogens in short-term bioassays, hepatic levels of cytochrome P-450 (CYP) and...

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Photocleavable Biotin Phosphoramidite for 5′-End-Labeling, Affinity Purification and Phosphorylation of Synthetic Oligonucleotides

Jerzy Olejnik, Edyta Krzymanska-Olejnik and Kenneth J. Rothschild.

in Nucleic Acids Research

January 1996; p ublished online January 1996 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 3526 words.

We report the design, synthesis and evaluation of a non-nucleosidic photocleavable biotin phosphoramidite (PCB-phosphoramidite) which provides a simple method for purification and...

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Microsomal metabolism and activation of the environmental carcinogen 2-amino-3-methyl-9H-pyrido[2,3-b]indole

Henrik Frandsen, Soren Damkjser, Spiros Grivas, Rolf Andersson, Mona-Lise Binderup and John C. Larsen.

in Mutagenesis

March 1998; p ublished online March 1998 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Genetics and Genomics. 0 words.

2-Amino-3-methyl-9H-pyrido[2,3-b]indole (MeAαC) is a mutagenic and carcinogenic heterocyclic amine formed as a pyrolysis product during cooking of food and combustion of tobacco. Hepatic...

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Protection against Trp-P-2 mutagenicity by purpurin: mechanism of in vitro antimutagenesis

Tim Marczylo, Sakae Arimoto-Kobayashi and Hikoya Hayatsu.

in Mutagenesis

May 2000; p ublished online May 2000 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Genetics and Genomics. 4837 words.

Purpurin (1,2,4-trihydroxy-9,10-anthraquinone) is a natural pigment isolated from madder root (Rubia tinctorum) which inhibits the mutagenicity of a number of heterocyclic amines in the...

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Genome Sequence of the Mesophilic Thermotogales Bacterium Mesotoga prima MesG1.Ag.4.2 Reveals the Largest Thermotogales Genome To Date

Olga Zhaxybayeva, Kristen S. Swithers, Julia Foght, Anna G. Green, David Bruce, Chris Detter, Shunsheng Han, Hazuki Teshima, James Han, Tanja Woyke, Sam Pitluck, Matt Nolan, Natalia Ivanova, Amrita Pati, Miriam L. Land, Marlena Dlutek, W. Ford Doolittle, Kenneth M. Noll and Camilla L. Nesbø.

in Genome Biology and Evolution

January 2012; p ublished online July 2012 .

Journal Article. Subjects: Bioinformatics and Computational Biology; Evolutionary Biology; Genetics and Genomics. 4349 words.

Here we describe the genome of Mesotoga prima MesG1.Ag4.2, the first genome of a mesophilic Thermotogales bacterium. Mesotoga prima was isolated from a polychlorinated biphenyl...

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In utero exposures to environmental organic pollutants disrupt epigenetic marks linked to fetoplacental development

Maya A. Kappil, Qian Li, An Li, Priyanthi S. Dassanayake, Yulin Xia, Jessica A. Nanes, Philip J. Landrigan, Christopher J. Stodgell, Kjersti M. Aagaard, Eric E. Schadt, Nancy Dole, Michael Varner, John Moye, Carol Kasten, Richard K. Miller, Yula Ma, Jia Chen and Luca Lambertini.

in Environmental Epigenetics

P ublished online February 2016 .

Journal Article. Subjects: Molecular Biology and Genetics; Biological Sciences; Developmental Biology; Evolutionary Biology; Genetics and Genomics. 4417 words.

While the developing fetus is largely shielded from the external environment through the protective barrier provided by the placenta, it is increasingly appreciated that environmental...

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DNA methylation: a mechanism linking environmental chemical exposures to risk of autism spectrum disorders?

Kimberly P. Keil and Pamela J. Lein.

in Environmental Epigenetics

P ublished online January 2016 .

Journal Article. Subjects: Molecular Biology and Genetics; Biological Sciences; Developmental Biology; Evolutionary Biology; Genetics and Genomics. 11847 words.

There is now compelling evidence that gene by environment interactions are important in the etiology of autism spectrum disorders (ASDs). However, the mechanisms by which environmental...

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