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St John's wort

Overview page. Subjects: Medicine and Health.

A homeopathic remedy for the treatment of depression and nerve damage. It is known to have an adverse effect by increasing the metabolism and elimination of other drugs that a patient may...

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St. John's Wort Extract Induces CYP3A and CYP2E1 in the Swiss Webster Mouse

B. J. Bray, N. B. Perry, D. B. Menkes and R. J. Rosengren.

in Toxicological Sciences

March 2002; p ublished online March 2002 .

Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 5510 words.

This investigation was designed to determine the ability of St. John's wort (SJW), a readily available antidepressant, to induce various hepatic drug metabolizing enzymes. SJW (140 or 280...

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hyperforin

Edited by Richard Cammack, Teresa Atwood, Peter Campbell, Howard Parish, Anthony Smith, Frank Vella and John Stirling.

in Oxford Dictionary of Biochemistry and Molecular Biology

January 2006; p ublished online January 2008 .

Reference Entry. Subjects: Biochemistry. 49 words.

the major active ingredient of the herb St John's wort, which is used as a herbal in a variety of

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Hyperforin Contributes to the Hepatic CYP3A-Inducing Effect of Hypericum perforatum Extract in the Mouse

Lavinia Cantoni, Marco Rozio, Alessandra Mangolini, Lisa Hauri and Silvio Caccia.

in Toxicological Sciences

September 2003; p ublished online September 2003 .

Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 4404 words.

This study in mice investigated whether hyperforin accounts for the inductive effects on cytochrome P4503A enzymes of St. John’s wort extracts (SJW; Hypericum perforatum), one of the most...

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