Oxford Index Search Results

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community x Clinical Cytogenetics and Molecular Genetics x clear all

community

Overview page. Subjects: Social Sciences — Arts and Humanities.

Many sociological and anthropological definitions exist, but most tend to privilege some combination of small-scale, relative boundedness, strong affective ties, traditionalism, and...

See overview in Oxford Index

Emerging roles of the microbiome in cancer

Scott J. Bultman.

in Carcinogenesis

February 2014; p ublished online December 2013 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 7637 words.

Gene–environment interactions underlie cancer susceptibility and progression. Yet, we still have limited knowledge of which environmental factors are important and how they function during...

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Glyphosate-based herbicides and cancer risk: a post-IARC decision review of potential mechanisms, policy and avenues of research

Michael J Davoren and Robert H Schiestl.

in Carcinogenesis

October 2018; p ublished online July 2018 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 9300 words.

Abstract

Since its initial sales in the 1970s, the herbicide glyphosate attained widespread use in modern agriculture, becoming the most commercially...

CYP2A6 reduced activity gene variants confer reduction in lung cancer risk in African American smokers—findings from two independent populations

Catherine A. Wassenaar, Yuanqing Ye, Qiuyin Cai, Melinda C. Aldrich, Joanne Knight, Margaret R. Spitz, Xifeng Wu, William J. Blot and Rachel F. Tyndale.

in Carcinogenesis

January 2015; p ublished online November 2014 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 4901 words.

We investigated genetic variation in CYP2A6 in relation to lung cancer risk among African American smokers, a high-risk population. Previously, we found that CYP2A6, a nicotine/nitrosamine...

Ceftriaxone, an FDA-approved cephalosporin antibiotic, suppresses lung cancer growth by targeting Aurora B

Xiang Li, Haitao Li, Shengqing Li, Feng Zhu, Dong Joon Kim, Hua Xie, Yan Li, Janos Nadas, Naomi Oi, Tatyana A. Zykova, Dong Hoon Yu, Mee-Hyun Lee, Myoung Ok Kim, Lei Wang, Weiya Ma, Ronald A. Lubet, Ann M. Bode, Ziming Dong and Zigang Dong.

in Carcinogenesis

December 2012; p ublished online September 2012 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 6485 words.

Ceftriaxone, an FDA-approved third-generation cephalosporin antibiotic, has antimicrobial activity against both gram-positive and gram-negative organisms. Generally, ceftriaxone is used for...

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The complex landscape of pancreatic cancer metabolism

Cristovão Marques Sousa and Alec C. Kimmelman.

in Carcinogenesis

July 2014; p ublished online April 2014 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 10920 words.

Pancreatic ductal adenocarcinomas (PDA) are extremely aggressive cancers and currently available therapies are only minimally effective in treating this disease. Tackling this devastating...

Modulation of the metabolism of airborne pollutants by glucoraphanin-rich and sulforaphane-rich broccoli sprout beverages in Qidong, China

Thomas W. Kensler, Derek Ng, Steven G. Carmella, Menglan Chen, Lisa P. Jacobson, Alvaro Muñoz, Patricia A. Egner, Jian Guo Chen, Geng Sun Qian, Tao Yang Chen, Jed W. Fahey, Paul Talalay, John D. Groopman, Jian-Min Yuan and Stephen S. Hecht.

in Carcinogenesis

January 2012; p ublished online November 2011 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 5526 words.

Epidemiological evidence has suggested that consumption of a diet rich in cruciferous vegetables reduces the risk of several types of cancers and chronic degenerative diseases. In...

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Alcohol metabolism and oesophageal cancer: a systematic review of the evidence

Marco Matejcic, Marc J Gunter and Pietro Ferrari.

in Carcinogenesis

September 2017; p ublished online June 2017 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 11467 words.

Abstract

Alcohol is a major risk factor for oesophageal squamous cell carcinoma (OSCC), the most prevalent histological subtype of oesophageal cancer (OC)...

Relationship between acetylator status, smoking, and diet and colorectal cancer risk in the north-east of England.

M R Welfare, J Cooper, M F Bassendine and A K Daly.

in Carcinogenesis

July 1997; p ublished online July 1997 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 0 words.

Some previous studies have suggested that the fast phenotype of the N-acetyltransferase NAT2 may confer susceptibility to colorectal cancer because of greater activation of dietary...

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Urinary 8-oxodeoxyguanosine, aflatoxin B1 exposure and hepatitis B virus infection and hepatocellular carcinoma in Taiwan

Hui-Chen Wu, Qiao Wang, Lian-Wen Wang, Hwai-I Yang, Habibul Ahsan, Wei-Yann Tsai, Li-Yu Wang, Shu-Yuan Chen, Chien-Jen Chen and Regina M. Santella.

in Carcinogenesis

May 2007; p ublished online November 2006 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 4688 words.

To evaluate the role of oxidative stress and aflatoxin exposure on risk of hepatocellular carcinoma (HCC), a case–control study nested within a community-based cohort was conducted in...

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Urinary 15-F2t-isoprostane, aflatoxin B1 exposure and hepatitis B virus infection and hepatocellular carcinoma in Taiwan

Hui-Chen Wu, Qiao Wang, Hwai-I Yang, Habibul Ahsan, Wei-Yann Tsai, Li-Yu Wang, Shu-Yuan Chen, Chien-Jen Chen and Regina M. Santella.

in Carcinogenesis

May 2008; p ublished online February 2008 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 4908 words.

To evaluate the role of oxidative stress and aflatoxin exposure on risk of hepatocellular carcinoma (HCC), a case–control study nested within a large community-based cohort was conducted in...

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Mycotoxins and human disease: a largely ignored global health issue

Christopher P. Wild and Yun Yun Gong.

in Carcinogenesis

January 2010; p ublished online October 2009 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 10679 words.

Aflatoxins and fumonisins (FB) are mycotoxins contaminating a large fraction of the world's food, including maize, cereals, groundnuts and tree nuts. The toxins frequently co-occur in...

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Global DNA methylation levels in white blood cells as a biomarker for hepatocellular carcinoma risk: a nested case–control study

Hui-Chen Wu, Qiao Wang, Hwai-I. Yang, Wei-Yann Tsai, Chien-Jen Chen and Regina M. Santella.

in Carcinogenesis

July 2012; p ublished online May 2012 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 5564 words.

Global DNA hypomethylation is associated with genomic instability and human cancer and blood DNAs collected at the time of cancer diagnosis have been used to examine the relationship...

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Plasma DNA methylation marker and hepatocellular carcinoma risk prediction model for the general population

Hui-Chen Wu, Hwai-I Yang, Qiao Wang, Chien-Jen Chen and Regina M Santella.

in Carcinogenesis

October 2017; p ublished online August 2017 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 6179 words.

Abstract

Metastases in the later stages of hepatocellular carcinoma (HCC) cause the majority of deaths associated with the disease, making early detection...

Glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) genetic polymorphism and susceptibility to gastric and colorectal adenocarcinoma

Takahiko Katoh, Naoki Nagata, Yusuke Kuroda, Hideaki Itoh, Akio Kawahara, Nobuyoshi Kuroki, Ryusuke Ookuma and Douglas A. Bell.

in Carcinogenesis

September 1996; p ublished online September 1996 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 0 words.

Genes coding for the glutatione S-transferase M1 (GSTM1) and Theta 1 (GSTT1) proteins are polymorphic in humans and these genes are absent, or homozygous ...

Increased cytogenetic damage in a zone in transition from agricultural to industrial use: comprehensive analysis of the micronucleus test in peripheral blood lymphocytes

Regina Montero, Luis Serrano, Antonio Araujo, Víctor Dávila, Johny Ponce, Rafael Camacho, Eduardo Morales and Alejandra Méndez.

in Mutagenesis

P ublished online September 2006 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Genetics and Genomics. 5909 words.

A complex situation of chemical exposure has been described in México in a zone that is in transition from rural activities towards intensive industrialization, which has brought...

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Potential thresholds for genotoxic effects by micronucleus scoring

Azeddine Elhajouji, Magdalena Lukamowicz, Zoryana Cammerer and Micheline Kirsch-Volders.

in Mutagenesis

January 2011; p ublished online January 2011 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Genetics and Genomics. 4864 words.

The concept of thresholds in genotoxicity has been open for debate in the last decades. The micronucleus (MN) test contributed to a large extent in understanding the dose–response...

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Recommendations for conducting the in vivo alkaline Comet assay

A. Hartmann, E. Agurell, C. Beevers, S. Brendler-Schwaab, B. Burlinson, P. Clay, A. Collins, A. Smith, G. Speit, V. Thybaud and R.R. Tice.

in Mutagenesis

January 2003; p ublished online January 2003 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Genetics and Genomics. 6244 words.

The in vivo alkaline single cell gel electrophoresis assay, hereafter the Comet assay, can be used to investigate the genotoxicity of industrial chemicals, biocides, agrochemicals and...

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Micronucleus assay in aquatic animals

Claudia Bolognesi and Makoto Hayashi.

in Mutagenesis

January 2011; p ublished online January 2011 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Genetics and Genomics. 6075 words.

Aquatic pollutants produce multiple consequences at organism, population, community and ecosystem level, affecting organ function, reproductive status, population size, species survival and...

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The use of dose-response data in a margin of exposure approach to carcinogenic risk assessment for genotoxic chemicals in food

Diane J. Benford.

in Mutagenesis

May 2016; p ublished online August 2015 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Genetics and Genomics. 1960 words.

Genotoxic substances are generally not permitted for deliberate use in food production. However, an appreciable number of known or suspected genotoxic substances occur unavoidably in food,...

Cell studies of the DNA bis-intercalator Δ-Δ [μ-C4(cpdppz)2-(phen)4Ru2]4+: toxic effects and properties as a light emitting DNA probe in V79 Chinese hamster cells

Björn Önfelt, Lovisa Göstring, Per Lincoln, Bengt Nordén and Agneta Önfelt.

in Mutagenesis

July 2002; p ublished online July 2002 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Genetics and Genomics. 2651 words.

Coordination complexes of type [Ru(L)3]2+, where L is a nitrogen-containing aromatic bidentate ligand, can often be photolytically reduced, making them useful in studies of DNA- or...

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