community
Overview page. Subjects: Social Sciences — Arts and Humanities.
Many sociological and anthropological definitions exist, but most tend to privilege some combination of small-scale, relative boundedness, strong affective ties, traditionalism, and...
Aflatoxin B1 Induced Compositional Changes in Gut Microbial Communities of Male F344 Rats
in Toxicological Sciences
March 2016; p ublished online November 2015 .
Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 6421 words.
Aflatoxins are a group of potent foodborne toxicants naturally occurring in maize and groundnuts. Differential species-specific sensitivity to aflatoxins has been documented but cannot be...
Metabonomics in Toxicology: A Review
in Toxicological Sciences
June 2005; p ublished online February 2005 .
Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 12547 words.
Metabonomics and its many pseudonyms (metabolomics, metabolic profiling, etc.) have exploded onto the scientific scene in the past 2 to 3 years. Nowhere has the impact been more profound...
Raising the Bar for Reproducible Science at the U.S. Environmental Protection Agency Office of Research and Development
in Toxicological Sciences
May 2015; p ublished online March 2015 .
Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 4638 words.
Considerable concern has been raised regarding research reproducibility both within and outside the scientific community. Several factors possibly contribute to a lack of reproducibility,...
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Internalization of Libby Amphibole Asbestos and Induction of Oxidative Stress in Murine Macrophages
in Toxicological Sciences
September 2007; p ublished online June 2007 .
Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 8689 words.
The community members of Libby, MT, have experienced significant asbestos exposure and developed numerous asbestos-related diseases including fibrosis and lung cancer due to an...
Challenges Associated With Applying Physiologically Based Pharmacokinetic Modeling for Public Health Decision-Making
in Toxicological Sciences
April 2018; p ublished online January 2018 .
Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 6496 words.
Abstract
The development and application of physiologically based pharmacokinetic (PBPK) models in chemical toxicology have grown steadily since their...
A Fatality Involving Zolpidem
in Journal of Analytical Toxicology
November 1997; p ublished online November 1997 .
Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 0 words.
An elderly woman residing in an independent-living retirement community was found dead in the bathtub. She had a history of depression and was prescribed Ambien® (generic name zolpidem) for...
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From the Editor's Desk
in Toxicological Sciences
November 2014; p ublished online November 2014 .
Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 2162 words.
I started composing these highlights while attending EUROTOX 2104 in Edinburgh, Scotland. Attending this meeting reminded me that Toxicological Sciences, while based in the U.S., is here to...
Workshop Proceedings: Managing Conflict of Interest in Science. A Little Consensus and A Lot of Controversy
in Toxicological Sciences
September 2005; p ublished online June 2005 .
Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 2567 words.
There is no doubt that participants in the Conflict of Interest (COI) Workshop at the Society of Toxicology (SOT) 2005 Annual Meeting (New Orleans, 6–10 March 2005) engaged in a vigorous...
Research Strategies for Safety Evaluation of Nanomaterials, Part III: Nanoscale Technologies for Assessing Risk and Improving Public Health
in Toxicological Sciences
December 2005; p ublished online September 2005 .
Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 5646 words.
Risk assessment in the environmental health sciences focuses on understanding the nature of environmental exposures and the potential harm posed by those exposures which in turn is...
Health Effects of Subchronic Exposure to Low Levels of Wood Smoke in Rats
in Toxicological Sciences
January 2002; p ublished online January 2002 .
Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 7724 words.
Wood smoke is a significant source of air pollution in many parts of the United States, and epidemiological data suggest a causal relationship between elevated wood smoke levels and health...
Methadone and Metabolite Urine Concentrations in Patients Maintained on Methadone
in Journal of Analytical Toxicology
September 2003; p ublished online September 2003 .
Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 0 words.
As regulatory control over methadone maintenance relaxes, the need for methods of monitoring compliance will increase. In community clinics, monitoring would most likely involve...
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The Analysis of Methyl Salicylate and Salicylic Acid from Chinese Herbal Medicine Ingestion
in Journal of Analytical Toxicology
April 2004; p ublished online April 2004 .
Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 0 words.
This paper presents a multi-drug fatality in which methyl salicylate was ingested. It is presented to inform the toxicological community that a particularly expeditious method of detection...
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The FAA's Postmortem Forensic Toxicology Self-Evaluated Proficiency Test Program: The Second Seven Years*
in Journal of Analytical Toxicology
May 2009; p ublished online May 2009 .
Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 0 words.
During toxicological evaluations of samples from fatally injured pilots involved in civil aviation accidents, a high degree of quality control/quality assurance (QC/QA) is maintained. Under...
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A Fatality Due to Cyproheptadine and Citalopram
in Journal of Analytical Toxicology
October 2009; p ublished online October 2009 .
Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 0 words.
Cyproheptadine (Periactin®) is a first-generation antihistamine available in over-the-counter cold medications and is used to treat allergic-type symptoms. Although antihistamines in...
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Domestic Abuse of the European Rave Drug Prolintane
in Journal of Analytical Toxicology
September 2007; p ublished online September 2007 .
Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 0 words.
Prolintane is a sympathomimetic amine with pharmacologic properties similar to d-amphetamine. Side effects include insomnia, nervousness, and irritability. Overdoses of prolintane may cause...
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Interference in the Quantitation of Methylated Arsenic Species in Human Urine
in Journal of Analytical Toxicology
March 1999; p ublished online March 1999 .
Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 0 words.
The aim of this paper is to report on the presence of chemical interferences in the quantitation of methylated arsenic species in human urine when using a method based on selective volatile...
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Postmortem Levetiracetam (Keppra) Data from North Carolina
in Journal of Analytical Toxicology
July 2012; p ublished online July 2012 .
Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 4361 words.
Levetiracetam (Keppra®) is one of the newer anticonvulsant drugs used to treat seizures. Since 2003, the North Carolina Office of the Chief Medical Examiner Toxicology Laboratory has...
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From the Editor's Desk
in Toxicological Sciences
October 2014; p ublished online October 2014 .
Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 3263 words.
One of the admirable aspects of science is that its practitioners accept that advancing the field is an ongoing process. There is always more to be discovered. I view scientific publishing...
From Science to Policy—When are Scientific Results Certain Enough?
in Toxicological Sciences
December 2006; p ublished online August 2006 .
Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 3328 words.
The amount of scientific findings linking air pollution with adverse health effects is continuously growing and indicates a need for action to improve air quality. On 21 September 2005, the...
Genetic Toxicity Assessment: Employing the Best Science for Human Safety Evaluation Part VI: When Salt and Sugar and Vegetables Are Positive, How Can Genotoxicity Data Serve to Inform Risk Assessment?
in Toxicological Sciences
August 2007; p ublished online March 2007 .
Journal Article. Subjects: Medical Toxicology; Toxicology (Non-medical). 3427 words.
This opinion piece examines the current approaches in the design and evaluation of genotoxicity data and recommends an alternative that would provide information that could be more useful...
