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complementation group

Overview page. Subjects: Genetics and Genomics.

Mutants lying within the same cistron; more properly called a noncomplementation group.

See overview in Oxford Index

Cohomology of Hyperplane Complements with Group Ring Coefficients

Michael W. Davis, Tadeusz Januszkiewicz, Ian J. Leary and Boris Okun.

in International Mathematics Research Notices

January 2011; p ublished online July 2010 .

Journal Article. Subjects: Mathematics. 1202 words.

We compute the cohomology with group ring coefficients of the complement of a finite collection of affine hyperplanes in . It is nonzero in exactly one degree, namely, the degree equal to...

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Homotopy groups of complements and nonisolated singularities

Anatoly Libgober and Mihai Tibăr.

in International Mathematics Research Notices

January 2002; p ublished online January 2002 .

Journal Article. Subjects: Mathematics. 0 words.

We study the topology of the level sets f = t, where f = 0 has a nonisolated singularity, in two cases: f is a polynomial function on ℂ n+1 with one atypical value, or f is a...

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complementation group

Overview page. Subjects: Genetics and Genomics.

Mutants lying within the same cistron; more properly called a noncomplementation group.

See overview in Oxford Index

complementation group

Robert C. King, William D. Stansfield and Pamela K. Mulligan.

in A Dictionary of Genetics

January 2007; p ublished online January 2007 .

Reference Entry. Subjects: Genetics and Genomics. 14 words.

mutants lying within the same cistron; more properly called a noncomplementation group.

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complementation group

Robert C. King, Pamela K. Mulligan and William D. Stansfield.

in A Dictionary of Genetics

January 2013; p ublished online January 2014 .

Reference Entry. Subjects: Genetics and Genomics. 14 words.

mutants lying within the same cistron; more properly called a noncomplementation group.

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Genetic and Molecular Definition of Complementation Group D in MHC Class II Deficiency

Marie-Claude Fondaneche, Jean Villard, Wojciech Wiszniewski, Emmanuelle Jouanguy, Amos Etzioni, Françoise Le Deist, Ad Peijnenburg, Jean-Laurent Casanova, Walter Reith, Bernard Mach, Alain Fischer and Barbara Lisowska-Grospierre.

in Human Molecular Genetics

May 1998; p ublished online May 1998 .

Journal Article. Subjects: Genetics and Genomics. 4117 words.

Four complementation groups, A, B, C and D, have been described among cell lines defective in the coordinate expression of MHC class II genes. These include cell lines established from...

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Mutations in PEX10 Is the Cause of Zellweger Peroxisome Deficiency Syndrome of Complementation Group B

Kanji Okumoto, Ryota Itoh, Nobuyuki Shimozawa, Yasuyuki Suzuki, Shigehiko Tamura, Naomi Kondo and Yukio Fujiki.

in Human Molecular Genetics

September 1998; p ublished online September 1998 .

Journal Article. Subjects: Genetics and Genomics. 4383 words.

Peroxisome biogenesis disorders (PBD), such as Zellweger syndrome, are autosomal recessive diseases caused by a deficiency in peroxisome assembly as well as a malfunction of the...

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Fancm-deficient mice reveal unique features of Fanconi anemia complementation group M

Sietske T. Bakker, Henri J. van de Vrugt, Martin A. Rooimans, Anneke B. Oostra, Jurgen Steltenpool, Elly Delzenne-Goette, Anja van der Wal, Martin van der Valk, Hans Joenje, Hein te Riele and Johan P. de Winter.

in Human Molecular Genetics

September 2009; p ublished online June 2009 .

Journal Article. Subjects: Genetics and Genomics. 7167 words.

The Fanconi anemia (FA) core complex member FANCM remodels synthetic replication forks and recombination intermediates. Thus far, only one FA patient with FANCM mutations has been...

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Damage-dependent regulation of MUS81-EME1 by Fanconi anemia complementation group A protein

Anaid Benitez, Fenghua Yuan, Satoshi Nakajima, Leizhen Wei, Liangyue Qian, Richard Myers, Jennifer J. Hu, Li Lan and Yanbin Zhang.

in Nucleic Acids Research

February 2014; p ublished online October 2013 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 6331 words.

MUS81-EME1 is a DNA endonuclease involved in replication-coupled repair of DNA interstrand cross-links (ICLs). A prevalent hypothetical role of MUS81-EME1 in ICL repair is to unhook the...

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Human Complement Bactericidal Responses to a Group A Meningococcal Conjugate Vaccine in Africans and Comparison to Responses Measured by 2 Other Group A Immunoassays

Gregory A. Price, Aimee M. Hollander, Brian D. Plikaytis, Brian T. Mocca, George Carlone, Helen Findlow, Ray Borrow, Samba O. Sow, Aldiouma Diallo, Olubukola T. Idoko, Godwin C. Enwere, Cheryl Elie, Marie-Pierre Preziosi, Prasad S. Kulkarni and Margaret C. Bash.

in Clinical Infectious Diseases

November 2015; p ublished online November 2015 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 5841 words.

Background.  PsA-TT (MenAfriVac) is a conjugated polysaccharide vaccine developed to eliminate group A meningococcal disease in Africa. Vaccination...

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Isolation of camptothecin-sensitive Chinese hamster cell mutants: phenotypic heterogeneity within the ataxia telangiectasia-like XRCC8 (irs2) complementation group

Mark A. Johnson, Peter E. Bryant and Nigel J. Jones.

in Mutagenesis

July 2000; p ublished online July 2000 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Genetics and Genomics. 6409 words.

Using a replica microwell method, four Chinese hamster lines which exhibit hypersensitivity to the topoisomerase I inhibitor camptothecin, designated CM1, CM2, CM3 and CM6, have been...

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Human Methionine Synthase: cDNA Cloning and Identification of Mutations in Patients of the cblG Complementation Group of Folate/Cobalamin Disorders

D. Leclerc, E. Campeau, P. Goyette, C. E. Adjalla, B. Christensen, M. Ross, P. Eydoux, D. S. Rosenblatt, R. Rozen and R. A. Gravel.

in Human Molecular Genetics

December 1996 .

Journal Article. Subjects: Genetics and Genomics. 3862 words.

Methionine synthase catalyzes the remethylation of homocysteine to methionine in a methylcobalamin-dependent reaction. We used specific regions of homology within the methionine synthase...

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Distribution of Streptococcal Inhibitor of Complement Variants in Pharyngitis and Invasive Isolates in an Epidemic of Serotype M1 Group A Streptococcus Infection

Nancy P. Hoe, Jaana Vuopio-Varkila, Martti Vaara, Diana Grigsby, David De Lorenzo, Yun-Xin Fu, Shu-Jun Dou, Xi Pan, Kazumitsu Nakashima and James M. Musser.

in The Journal of Infectious Diseases

February 2001; p ublished online February 2001 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 4204 words.

Streptococcal inhibitor of complement (Sic) is a highly polymorphic extracellular protein made predominantly by serotype M1 group A Streptococcus (GAS). New variants of the Sic protein...

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Identification of the gene responsible for the cblB complementation group of vitamin B12-dependent methylmalonic aciduria

C. Melissa Dobson, Timothy Wai, Daniel Leclerc, Hakan Kadir, Monica Narang, Jordan P. Lerner-Ellis, Thomas J. Hudson, David S. Rosenblatt and Roy A. Gravel.

in Human Molecular Genetics

December 2002; p ublished online December 2002 .

Journal Article. Subjects: Genetics and Genomics. 5789 words.

The methylmalonic acidurias are metabolic disorders resulting from deficient methylmalonyl-CoA mutase activity, a vitamin B12-dependent enzyme. We have cloned the gene for the cblB complemen...

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Nonsense and Temperature-Sensitive Mutations in PEX13 are the Cause of Complementation Group H of Peroxisome Biogenesis Disorders

Nobuyuki Shimozawa, Yasuyuki Suzuki, Zhongyi Zhang, Atsushi Imamura, Ryusuke Toyama, Satoru Mukai, Yukio Fujiki, Toshiro Tsukamoto, Takashi Osumi, Tadao Orii, Ronald J. A. Wanders and Naomi Kondo.

in Human Molecular Genetics

June 1999; p ublished online June 1999 .

Journal Article. Subjects: Genetics and Genomics. 4147 words.

Peroxisome biogenesis disorders, including Zellweger syndrome (ZS), neonatal adrenoleukodys-trophy (NALD) and infantile Refsum disease, are lethal hereditary diseases caused by...

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Molecular Basis for Methionine Synthase Reductase Deficiency in Patients Belonging to the cblE Complementation Group of Disorders in Folate/Cobalamin Metabolism

A. Wilson, D. Leclerc, D.S. Rosenblatt and R.A. Gravel.

in Human Molecular Genetics

October 1999; p ublished online October 1999 .

Journal Article. Subjects: Genetics and Genomics. 5547 words.

Methionine synthase reductase (MSR) deficiency is an autosomal recessive disorder of folate/cobalamin metabolism leading to hyperhomocysteinemia, hypo-methioninemia and megaloblastic...

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Prognostic Significance of X-ray Cross-complementing Group 1 T-77C Polymorphism in Resected Non-small Cell Lung Cancer

Wei-Chung Hsieh, Ya-Wen Cheng, Cuei-Jyuan Lin, Ming-Chih Chou, Chih-Yi Chen and Huei Lee.

in Japanese Journal of Clinical Oncology

February 2009; p ublished online December 2008 .

Journal Article. Subjects: Medical Oncology. 3027 words.

Objective

A novel T-77C polymorphism in the promoter region of the DNA repair gene X-ray cross-complementing group 1 (XRCC1) may modulate its transcription...

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Rodent UV-Sensitive Mutant Cell Lines in Complementation Groups 6–10 Have Normal General Excision Repair Activity

Joyce T. Reardon, Larry H. Thompson and Aziz Sancar.

in Nucleic Acids Research

March 1997; p ublished online March 1997 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 4239 words.

Mammalian nucleotide excision repair is the primary enzymatic pathway for removing bulky lesions from DNA. The repair reaction involves three main steps: (i) dual incisions on both sides of...

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Human Immune Response to Streptococcal Inhibitor of Complement, a Serotype M1 Group A Streptococcus Extracellular Protein Involved in Epidemics

Nancy P. Hoe, Parichher Kordari, Robert Cole, Mengyao Liu, Timothy Palzkill, Wanzhi Huang, Duncan McLellan, Gerald J. Adams, Mary Hu, Jaana Vuopio-Varkila, Thomas R. Cate, Michael E. Pichichero, Kathryn M. Edwards, Juhani Eskola, Donald E. Low and James M. Musser.

in The Journal of Infectious Diseases

November 2000; p ublished online November 2000 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 8259 words.

Streptococcal inhibitor of complement (Sic) is a highly polymorphic extracellular protein made by serotype M1 group A Streptococcus strains that contributes to bacterial persistence in the...

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Fanconi anemia, complementation group A, cells are defective in ability to produce incisions at sites of psoralen interstrand cross-links

Kandallu R. Kumaresan and Muriel W. Lambert.

in Carcinogenesis

April 2000; p ublished online April 2000 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 8769 words.

The hypersensitivity of Fanconi anemia, complementation group A, (FA-A) cells to agents which produce DNA interstrand cross-links correlates with a defect in their ability to repair this...

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