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complementation group x Medical Oncology x clear all

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complementation group

Overview page. Subjects: Genetics and Genomics.

Mutants lying within the same cistron; more properly called a noncomplementation group.

See overview in Oxford Index

Prognostic Significance of X-ray Cross-complementing Group 1 T-77C Polymorphism in Resected Non-small Cell Lung Cancer

Wei-Chung Hsieh, Ya-Wen Cheng, Cuei-Jyuan Lin, Ming-Chih Chou, Chih-Yi Chen and Huei Lee.

in Japanese Journal of Clinical Oncology

February 2009; p ublished online December 2008 .

Journal Article. Subjects: Medical Oncology. 3027 words.

Objective

A novel T-77C polymorphism in the promoter region of the DNA repair gene X-ray cross-complementing group 1 (XRCC1) may modulate its transcription...

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Impact of excision repair cross-complementing gene 1 (ERCC1) on the outcomes of patients with advanced gastric cancer: correlative study in Japan Clinical Oncology Group Trial JCOG9912

Y. Yamada, N. Boku, T. Nishina, K. Yamaguchi, T. Denda, A. Tsuji, Y. Hamamoto, K. Konishi, Y. Tsuji, K. Amagai, S. Ohkawa, Y. Fujita, H. Nishisaki, H. Kawai, A. Takashima, J. Mizusawa, K. Nakamura and A. Ohtsu.

in Annals of Oncology

October 2013; p ublished online July 2013 .

Journal Article. Subjects: Medical Oncology. 3213 words.

Background

Since the best chemotherapy regimen for each patient with advanced gastric cancer is uncertain, we aimed to identify molecular prognostic or...

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NC-08PREDICTORS OF SURVIVAL AFTER SECOND SURGERY FOR RECURRENT GLIOBLASTOMA MULTIFORME TUMOURS

Alexandra Kilian, Kashif Parvex, Eric Monsalves, Soroush Larjani, George Klironomos and Gelareh Zadeh.

in Neuro-Oncology

November 2014; p ublished online November 2014 .

Journal Article. Subjects: Medical Oncology; Neurology. 0 words.

BACKGROUND AND PURPOSE: The impact of second surgery and overall predictors of outcome following GBM recurrence remains controversial, with few definitive studies published to date. This...

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Predictive Effects of ERCC1 and XRCC3 SNP on Efficacy of Platinum-based Chemotherapy in Advanced NSCLC Patients

Caicun Zhou, Shengxiang Ren, Songwen Zhou, Ling Zhang, Cunxia Su, Zengli Zhang, Qinfang Deng and Jie Zhang.

in Japanese Journal of Clinical Oncology

October 2010; p ublished online May 2010 .

Journal Article. Subjects: Medical Oncology. 3299 words.

Objective

The purpose of the study was to investigate whether single-nucleotide polymorphisms of deoxyribonucleic acid repair gene excision repair...

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The association of DNA repair gene polymorphisms with the development and progression of renal cell carcinoma

S. Sakano, Y. Hinoda, N. Okayama, Y. Kawai, Y. Korenaga, S. Eguchi, K. Nagao, C. Ohmi and K. Naito.

in Annals of Oncology

November 2007; p ublished online August 2007 .

Journal Article. Subjects: Medical Oncology. 5435 words.

Background: DNA repair enzymes repair some of the DNA damage associated with risk factors for renal cell carcinoma (RCC), including smoking. DNA repair gene polymorphisms...

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Polymorphisms in DNA repair genes modulate survival in cisplatin/gemcitabine-treated non-small-cell lung cancer patients

R. de las Peñas, M. Sanchez-Ronco, V. Alberola, M. Taron, C. Camps, R. Garcia-Carbonero, B. Massuti, C. Queralt, M. Botia, R. Garcia-Gomez, D. Isla, M. Cobo, M. Santarpia, F. Cecere, P. Mendez, J. J. Sanchez and R. Rosell.

in Annals of Oncology

April 2006; p ublished online January 2006 .

Journal Article. Subjects: Medical Oncology. 4778 words.

Background: Impaired DNA repair capacity may favorably affect survival in cisplatin/gemcitabine-treated non-small-cell lung cancer (NSCLC) patients. We investigated the...

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Best practices for the management of local-regional recurrent chordoma: a position paper by the Chordoma Global Consensus Group

S. Stacchiotti, A. Gronchi, P. Fossati, T. Akiyama, C. Alapetite, M. Baumann, J. Y. Blay, S. Bolle, S. Boriani, P. Bruzzi, R. Capanna, A. Caraceni, R. Casadei, V. Colia, J. Debus, T. Delaney, A. Desai, P. Dileo, S. Dijkstra, F. Doglietto, A. Flanagan, S. Froelich, P. A. Gardner, H. Gelderblom, Z. L. Gokaslan, R. Haas, C. Heery, N. Hindi, P. Hohenberger, F. Hornicek, R. Imai, L. Jeys, R. L. Jones, B. Kasper, A. Kawai, M. Krengli, A. Leithner, I. Logowska, J. Martin Broto, D. Mazzatenta, C. Morosi, P. Nicolai, O. J. Norum, S. Patel, N. Penel, P. Picci, S. Pilotti, S. Radaelli, F. Ricchini, P. Rutkowski, S. Scheipl, C. Sen, E. Tamborini, K. A. Thornton, B. Timmermann, V. Torri, P. U. Tunn, M. Uhl, Y. Yamada, D. C. Weber, D. Vanel, P. P. Varga, C. L. A. Vleggeert-Lankamp, P. G. Casali and J. Sommer.

in Annals of Oncology

June 2017; p ublished online February 2017 .

Journal Article. Subjects: Medical Oncology. 7499 words.

Chordomas are rare, malignant bone tumors of the skull-base and axial skeleton. Until recently, there was no consensus among experts regarding appropriate clinical management of chordoma,...

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Visualizing Length of Survival in Time-to-Event Studies: A Complement to Kaplan–Meier Plots

Patrick Royston, Mahesh K. B. Parmar and Douglas G. Altman.

in JNCI: Journal of the National Cancer Institute

January 2008; p ublished online January 2008 .

Journal Article. Subjects: Medical Oncology. 3985 words.

Because of censoring, standard methods of plotting individual survival times are invalid. Therefore, graphic display of time-to-event data usually takes the form of a Kaplan–Meier survival...

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Mature B-cell lymphoma/leukemia in children and adolescents: Intergroup pathologist consensus with the Revised European—American Lymphoma Classification*

M.A. Lones, A. Auperin, M. Raphael, K. McCarthy, S.L. Perkins, K.A. MacLennan, A. Ramsay, A. Wotherspoon, M. Gerrard, M.S. Cairo and C. Patte.

in Annals of Oncology

January 2000; p ublished online January 2000 .

Journal Article. Subjects: Medical Oncology. 0 words.

Background: The Revised European-American Lymphoma (R.E.A.L.) Classification criteria were evaluated in the international protocol FAB LMB 96 Treatment of Mature B-Cell...

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EGF61A>G polymorphism as predictive marker of clinical outcome to first-line capecitabine and oxaliplatin in metastatic colorectal cancer

K.-L. G. Spindler, R. F. Andersen, L. H. Jensen, J. Ploen and A. Jakobsen.

in Annals of Oncology

March 2010; p ublished online October 2009 .

Journal Article. Subjects: Medical Oncology. 2879 words.

Background: The purpose of the present study was to investigate polymorphisms related to the metabolism of fluoropyrimidine and oxaliplatin, thymidylate synthase (TS) and...

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The NER proteins are differentially expressed in ever smokers and in never smokers with lung adenocarcinoma

D. Planchard, J. Domont, E. Taranchon, I. Monnet, J. Tredaniel, R. Caliandro, P. Validire, B. Besse, J.-C. Soria and P. Fouret.

in Annals of Oncology

July 2009; p ublished online March 2009 .

Journal Article. Subjects: Medical Oncology. 4095 words.

Background: The expression levels of excision repair cross-complementation group 1 (ERCC1), replication protein A (RPA) and xeroderma pigmentosum group F (XPF) nucleotide...

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A Case Report of Pathologically Complete Response of a Huge Rectal Cancer after Systemic Chemotherapy with mFOLFOX6

Kae Okoshi, Satoshi Nagayama, Moritoshi Furu, Yukiko Mori, Akihiko Yoshizawa, Junya Toguchida and Yoshiharu Sakai.

in Japanese Journal of Clinical Oncology

August 2009; p ublished online June 2009 .

Journal Article. Subjects: Medical Oncology. 2923 words.

A 54-year-old man was referred to our hospital because of a huge, unresectable rectal cancer occupying his entire pelvic space with a solitary liver metastasis. He had undergone a...

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Complement activation following first exposure to pegylated liposomal doxorubicin (Doxil®): possible role in hypersensitivity reactions

A. Chanan-Khan, J. Szebeni, S. Savay, L. Liebes, N. M. Rafique, C. R. Alving and F. M. Muggia.

in Annals of Oncology

September 2003; p ublished online September 2003 .

Journal Article. Subjects: Medical Oncology. 5086 words.

Background:

Pegylated liposomal doxorubicin (Doxil®) has been reported to cause immediate hypersensitivity reactions (HSRs) that cannot be explained as...

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ERCC1 and histopathology in advanced NSCLC patients randomized in a large multicenter phase III trial

A. C. Vilmar, E. Santoni-Rugiu and J. B. Sørensen.

in Annals of Oncology

September 2010; p ublished online March 2010 .

Journal Article. Subjects: Medical Oncology. 4084 words.

Background: Customized chemotherapy is likely to improve outcome in patients with advanced non-small-cell lung cancer (NSCLC). Excision repair cross-complementation group 1...

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Multicenter phase II study of gemcitabine and oxaliplatin in advanced nasopharyngeal carcinoma—correlation with excision repair cross-complementing-1 polymorphisms

B. B. Y. Ma, E. P. Hui, S. C. C. Wong, S. Y. Tung, K. K. Yuen, A. King, S. L. Chan, S. F. Leung, M. K. Kam, B. K. H. Yu, B. Zee and A. T. C. Chan.

in Annals of Oncology

November 2009; p ublished online June 2009 .

Journal Article. Subjects: Medical Oncology. 3898 words.

Background: Nasopharyngeal carcinoma (NPC) is a platinum-sensitive cancer and excision repair cross-complementing group 1 (ERCC1) polymorphisms have been shown to predict...

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Screening and early—detection of lung cancer

J. Vansteenkiste, C. Dooms, C. Mascaux and K. Nackaerts.

in Annals of Oncology

September 2012; p ublished online September 2012 .

Journal Article. Subjects: Medical Oncology. 5647 words.

The greatest news of the past year in this field was the first large-scale early detection trial that could prove a 20% reduction in lung cancer-related mortality by screening high-risk...

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Overexpression of BLM promotes DNA damage and increased sensitivity to platinum salts in triple-negative breast and serous ovarian cancers

N J Birkbak, Y Li, S Pathania, A Greene-Colozzi, M Dreze, C Bowman-Colin, Z Sztupinszki, M Krzystanek, M Diossy, N Tung, P D Ryan, J E Garber, D P Silver, J D Iglehart, Z C Wang, D Szuts, Z Szallasi and A L Richardson.

in Annals of Oncology

April 2018; p ublished online February 2018 .

Journal Article. Subjects: Medical Oncology. 3812 words.

Abstract

Background

Platinum-based therapy is an effective treatment for a subset of triple-negative breast cancer...

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Alcohol Drinking and Breast Cancer Risk: An Evaluation Based on a Systematic Review of Epidemiologic Evidence among the Japanese Population

Chisato Nagata, Tetsuya Mizoue, Keitaro Tanaka, Ichiro Tsuji, Kenji Wakai, Manami Inoue and Shoichiro Tsugane.

in Japanese Journal of Clinical Oncology

August 2007; p ublished online August 2007 .

Journal Article. Subjects: Medical Oncology. 2957 words.

Background

We reviewed epidemiological studies on alcohol drinking and breast cancer among the Japanese population. This report is one among a series of...

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Alcohol Drinking and Gastric Cancer Risk: An Evaluation Based on a Systematic Review of Epidemiologic Evidence among the Japanese Population

Taichi Shimazu, Ichiro Tsuji, Manami Inoue, Kenji Wakai, Chisato Nagata, Tetsuya Mizoue, Keitaro Tanaka and Shoichiro Tsugane.

in Japanese Journal of Clinical Oncology

January 2008; p ublished online January 2008 .

Journal Article. Subjects: Medical Oncology. 5211 words.

Background

We reviewed epidemiologic studies on the association between alcohol drinking and gastric cancer among the Japanese population. This report is...

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Breastfeeding and Breast Cancer Risk: An Evaluation Based on a Systematic Review of Epidemiologic Evidence Among the Japanese Population

Chisato Nagata, Tetsuya Mizoue, Keitaro Tanaka, Ichiro Tsuji, Akiko Tamakoshi, Kenji Wakai, Keitaro Matsuo, Hidemi Ito, Shizuka Sasazuki, Manami Inoue and Shoichiro Tsugane.

in Japanese Journal of Clinical Oncology

February 2012; p ublished online December 2011 .

Journal Article. Subjects: Medical Oncology. 2815 words.

Objective

We reviewed epidemiological studies on breastfeeding and breast cancer among Japanese women. This report is part of a series of articles written by...

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