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desensitization x Clinical Cytogenetics and Molecular Genetics x clear all

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Overview page. Subjects: Sports and Exercise Medicine.

A stress-management technique, more accurately called systematic desensitization, which uses relaxation techniques to cope with anxiety-inducing situations. The subject compiles a...

See overview in Oxford Index

The duration of phorbol-inducible ErbB2 tyrosine dephosphorylation parallels that of receptor endocytosis rather than threonine-686 phosphorylation: implications for the physiological role of protein kinase C in growth factor receptor signalling.

X Ouyang, T Gulliford and R J Epstein.

in Carcinogenesis

November 1998; p ublished online November 1998 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 0 words.

Tumour cell growth may be accelerated by protein kinase C (PKC) agonists such as phorbol esters and receptor tyrosine kinases, but receptor tyrosine kinases are in turn desensitized to...

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Extracellular zinc and zinc-citrate, acting through a putative zinc-sensing receptor, regulate growth and survival of prostate cancer cells

Noga Dubi, Larisa Gheber, Daniel Fishman, Israel Sekler and Michal Hershfinkel.

in Carcinogenesis

September 2008; p ublished online February 2008 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 7271 words.

Prostate Zn2+ concentrations are among the highest in the body, and a marked decrease in the level of this ion is observed in prostate cancer. Extracellular Zn2+ is known to regulate cell...

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MAP17 enhances the malignant behavior of tumor cells through ROS increase

Maria V. Guijarro, Juan F.M. Leal, Carmen Blanco-Aparicio, Soledad Alonso, Jesús Fominaya, Matilde Lleonart, Josep Castellvi, Santiago Ramon y Cajal and Amancio Carnero.

in Carcinogenesis

October 2007; p ublished online June 2007 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 6369 words.

Tumorigenesis occurs when the mechanisms involved in the control of tissue homeostasis are disrupted and cells stop responding to physiological signals. Therefore, genes capable of...

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Effects of chronic nicotine on the autocrine regulation of pancreatic cancer cells and pancreatic duct epithelial cells by stimulatory and inhibitory neurotransmitters

Mohammed H. Al-Wadei, Hussein A.N. Al-Wadei and Hildegard M. Schuller.

in Carcinogenesis

September 2012; p ublished online July 2012 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 6082 words.

Pancreatic ductal adenocarcinoma (PDAC) has a mortality rate near 100%. Smoking is a documented risk factor. However, the mechanisms of smoking-associated pancreatic carcinogenesis are...

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The prostaglandin receptor EP2 activates multiple signaling pathways and β-arrestin1 complex formation during mouse skin papilloma development

Kyung-Soo Chun, Huei-Chen Lao, Carol S. Trempus, Manabu Okada and Robert Langenbach.

in Carcinogenesis

September 2009; p ublished online July 2009 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 6441 words.

Prostaglandin E2 (PGE2) is elevated in many tumor types, but PGE2's contributions to tumor growth are largely unknown. To investigate PGE2's roles, the contributions of one of its...

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De novo variants in GABRA2 and GABRA5 alter receptor function and contribute to early-onset epilepsy

Kameryn M Butler, Olivia A Moody, Elisabeth Schuler, Jason Coryell, John J Alexander, Andrew Jenkins and Andrew Escayg.

in Brain

August 2018; p ublished online June 2018 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Molecular and Cellular Systems. 8589 words.


GABAA receptors are ligand-gated anion channels that are important regulators of neuronal inhibition. Mutations in several genes encoding receptor...

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