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formin

Overview page. Subjects: Medicine and Health — Chemistry.

A conserved protein family originally identified as alternatively spliced products of the ld (limb deformity) locus of the mouse, mutations in which disrupt pattern formation, cause limb...

See overview in Oxford Index

formin

Overview page. Subjects: Medicine and Health — Chemistry.

A conserved protein family originally identified as alternatively spliced products of the ld (limb deformity) locus of the mouse, mutations in which disrupt pattern formation, cause limb...

See overview in Oxford Index

formins

John Lackie.

in A Dictionary of Biomedicine

January 2010; p ublished online January 2010 .

Reference Entry. Subjects: Clinical Medicine. 86 words.

A conserved protein family originally identified as alternatively spliced products of the ld (limb deformity) locus of the mouse, mutations in which disrupt pattern formation, cause limb...

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formin

Edited by Richard Cammack, Teresa Atwood, Peter Campbell, Howard Parish, Anthony Smith, Frank Vella and John Stirling.

in Oxford Dictionary of Biochemistry and Molecular Biology

January 2006; p ublished online January 2008 .

Reference Entry. Subjects: Biochemistry. 44 words.

one of several developmental nuclear phosphoproteins found in several tissue types. They are formed by alternative splicing of the mouse

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Formin1 disruption confers oligodactylism and alters Bmp signaling

Fen Zhou, Philip Leder, Aimée Zuniga and Markus Dettenhofer.

in Human Molecular Genetics

July 2009; p ublished online April 2009 .

Journal Article. Subjects: Genetics and Genomics. 6925 words.

Proper limb development requires concerted communication between cells within the developing limb bud. Several molecules have been identified which contribute to the formation of a...

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AtFH1 formin mutation affects actin filament and microtubule dynamics in Arabidopsis thaliana

Amparo Rosero, Viktor Žárský and Fatima Cvrčková.

in Journal of Experimental Botany

January 2013; p ublished online December 2012 .

Journal Article. Subjects: Plant Sciences and Forestry. 6790 words.

Plant cell growth and morphogenesis depend on remodelling of both actin and microtubule cytoskeletons. AtFH1 (At5g25500), the main housekeeping Arabidopsis formin, is targeted to membranes...

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Characterization of the Arabidopsis Formin-Like Protein AFH1 and Its Interacting Protein

Hiroharu Banno and Nam-Hai Chua.

in Plant and Cell Physiology

May 2000; p ublished online May 2000 .

Journal Article. Subjects: Biochemistry; Molecular and Cell Biology; Plant Sciences and Forestry. 0 words.

A partial cDNA encoding an Arabidopsis thaliana FH (Formin Homology) protein (AFH1) was used as a probe to clone a full length AFH1 cDNA. The deduced protein encoded by the cDNA contains a...

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Origins and Evolution of the Formin Multigene Family That Is Involved in the Formation of Actin Filaments

Dimitra Chalkia, Nikolas Nikolaidis, Wojciech Makalowski, Jan Klein and Masatoshi Nei.

in Molecular Biology and Evolution

December 2008; p ublished online October 2008 .

Journal Article. Subjects: Evolutionary Biology; Molecular and Cell Biology. 9628 words.

In eukaryotes, the assembly and elongation of unbranched actin filaments is controlled by formins, which are long, multidomain proteins. These proteins are important for dynamic cellular...

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EXTH-31. TARGETING THE FORMIN-DIRECTED CYTOSKELETON WITH SMALL MOLECULE AGONISTS BLOCKS GLIOBLASTOMA PATIENT-DERIVED NEUROSPHERE INVASION

Kathryn Eisenmann, Jason Schroeder, Krista Pettee, Kathryn Becker and Christine Sattler.

in Neuro-Oncology

November 2018; p ublished online November 2018 .

Journal Article. Subjects: Medical Oncology; Neurology. 0 words.

Abstract

Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor in adults and aggressive treatment only extends survival by months....

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Formin 1 and Filamin B physically interact to coordinate chondrocyte proliferation and differentiation in the growth plate

Jianjun Hu, Jie Lu, Gewei Lian, Russell J. Ferland, Markus Dettenhofer and Volney L. Sheen.

in Human Molecular Genetics

September 2014; p ublished online April 2014 .

Journal Article. Subjects: Genetics and Genomics. 6105 words.

Filamin B (FlnB) is an actin-binding protein thought to transduce signals from various membrane receptors and intracellular proteins onto the actin cytoskeleton. Formin1 (Fmn1) is an...

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diaphanous

John Lackie.

in A Dictionary of Biomedicine

January 2010; p ublished online January 2010 .

Reference Entry. Subjects: Clinical Medicine. 100 words.

The product of the Drosophila gene diaphanous, the first member of a family of proteins, the diaphanous-related formins (Drfs; DRF1 and DRF2 in humans) that act as ...

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diaphanous

Overview page. Subjects: Medicine and Health — Chemistry.

The product of the Drosophila gene diaphanous, the first member of a family of proteins, the diaphanous-related formins (Drfs; DRF1 and DRF2 in humans) that act as rho GTPase effectors...

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Protein–protein interactions as a proxy to monitor conformational changes and activation states of the tomato resistance protein I-2

Ewa Lukasik-Shreepaathy, Jack H. Vossen, Wladimir I. L. Tameling, Marianne J. de Vroomen, Ben J. C. Cornelissen and Frank L. W. Takken.

in Journal of Experimental Botany

May 2012; p ublished online February 2012 .

Journal Article. Subjects: Plant Sciences and Forestry. 9813 words.

Plant resistance proteins (R) are involved in pathogen recognition and subsequent initiation of defence responses. Their activity is regulated by inter- and intramolecular interactions. In...

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From Nationalist Peace to Democratic War

Thomas Hippler.

in Paradoxes of Peace in Nineteenth Century Europe

February 2015; p ublished online April 2015 .

Chapter. Subjects: Jurisprudence and Philosophy of Law; History of Law. 9529 words.

This chapter illustrates how the Holy Alliance and its Troppau Protocol express a principle which can be found—sometimes in disguised form—in virtually all ulterior peace movements: the...

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AtFH8 Is Involved in Root Development under Effect of Low-Dose Latrunculin B in Dividing Cells

Xiu-Hua Xue, Chun-Qing Guo, Fei Du, Quan-Long Lu, Chuan-Mao Zhang and Hai-Yun Ren.

in Molecular Plant

March 2011; p ublished online February 2011 .

Journal Article. Subjects: Molecular and Cell Biology; Plant Sciences and Forestry. 8351 words.

Formins have been paid much attention for their potent nucleating activity. However, the connection between the in vivo functions of AtFHs (Arabidopsis thaliana formin homologs) and their...

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Talking Tools, Femina narrans, and the Irrepressibility of Women

Coralynn V. Davis.

in Maithil Women's Tales

July 2014; p ublished online April 2017 .

Chapter. Subjects: Society and Culture. 11882 words.

This concluding chapter looks at what happens in Maithil women's folktales when stories of women's suffering at the hands of other women are first suppressed and later overheard by men who...

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Subject

Paul M. Walker.

in Oxford Music Online

January 2001; p ublished online January 2001 .

Reference Entry. Subjects: Musical Form. 344 words.

A theme (or group of themes) on which a composition is based. One of the first to apply the word ‘subject’ to music was Zarlino, who in Le istitutioni harmoniche (1558) defined it, using...

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Foundationalism and the Phenomenology of Perception

Christian Coseru.

in Perceiving Reality

September 2012; p ublished online January 2013 .

Chapter. Subjects: Buddhism. 19159 words.

This chapter, which draws on a set of interrelated issues in the phenomenology of perception, calls into question the assumption that Buddhist philosophers of the Dignāga-Dharmakīrti...

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Discrimination and Labour Law: Locating the Market in Maldistribution and Subordination

Noah D Zatz.

in Philosophical Foundations of Labour Law

December 2018; p ublished online February 2019 .

Chapter. Subjects: Employment and Labour Law. 11098 words.

Labour law doctrine has fully incorporated discrimination, but labour law theory has not. Market ordering is labour law’s villain, but employment discrimination theory often casts market...

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The Third Origin

Roberto Esposito.

in The Origin of the Political

April 2017; p ublished online September 2017 .

Chapter. Subjects: Political Theory. 2580 words.

This chapter argues that the double operation involving the urbanization of originary conflict and the “heroization” of political action is not yet sufficient to bridge the principle gap...

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The Form-Pleasure

Jean-Luc Nancy.

in The Pleasure in Drawing

July 2013; p ublished online September 2013 .

Chapter. Subjects: Aesthetics and Philosophy of Art. 2429 words.

This section discusses pleasure by drawing on Sigmund Freud’s work on the subject of aesthetic form, particularly his notion of sexual pleasure as opposed to aesthetic pleasure. Freud views...

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