Oxford Index Search Results

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founder x Genetics and Genomics x clear all

founder

Overview page. Subjects: Warfare and Defence — Maritime History.

Of a ship, to sink at sea, generally understood to be by the flooding of its hull either through springing a leak or through striking a rock. Other causes of a ship sinking, such as...

See overview in Oxford Index

founder cells

Robert C. King, William D. Stansfield and Pamela K. Mulligan.

in A Dictionary of Genetics

January 2007; p ublished online January 2007 .

Reference Entry. Subjects: Genetics and Genomics. 4 words.

founder effect

Robert C. King, William D. Stansfield and Pamela K. Mulligan.

in A Dictionary of Genetics

January 2007; p ublished online January 2007 .

Reference Entry. Subjects: Genetics and Genomics. 92 words.

the principle that when a small sample of a larger population establishes itself as a newly isolated entity, its gene

founder effect

Robert C. King, Pamela K. Mulligan and William D. Stansfield.

in A Dictionary of Genetics

January 2013; p ublished online January 2014 .

Reference Entry. Subjects: Genetics and Genomics. 93 words.

the principle that when a small sample of a larger population establishes itself as a newly isolated entity, its gene

founder cells

Robert C. King, Pamela K. Mulligan and William D. Stansfield.

in A Dictionary of Genetics

January 2013; p ublished online January 2014 .

Reference Entry. Subjects: Genetics and Genomics. 4 words.

An ancient founder mutation in PROKR2 impairs human reproduction

Magdalena Avbelj Stefanija, Marc Jeanpierre, Gerasimos P. Sykiotis, Jacques Young, Richard Quinton, Ana Paula Abreu, Lacey Plummer, Margaret G. Au, Ravikumar Balasubramanian, Andrew A. Dwyer, Jose C. Florez, Timothy Cheetham, Simon H. Pearce, Radhika Purushothaman, Albert Schinzel, Michel Pugeat, Elka E. Jacobson-Dickman, Svetlana Ten, Ana Claudia Latronico, James F. Gusella, Catherine Dode, William F. Crowley and Nelly Pitteloud.

in Human Molecular Genetics

October 2012; p ublished online July 2012 .

Journal Article. Subjects: Genetics and Genomics. 5848 words.

Congenital gonadotropin-releasing hormone (GnRH) deficiency manifests as absent or incomplete sexual maturation and infertility. Although the disease exhibits marked locus and allelic...

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Epistasis for Founder-Specific Inbreeding Depression in Rabbits

Joaquim Casellas, Dolors Vidal-Roqueta, Eva Flores, Dolors Casellas-Vidal, MarÇal Llach-Vila, Roser Salgas-Fina and Pere Casellas-Molas.

in Journal of Heredity

January 2011; p ublished online December 2010 .

Journal Article. Subjects: Genetics and Genomics. 4686 words.

Inbreeding depression is a topic of main interest in experimental and domestic species, although previous studies simplified this genetically complex effect to the linear (or quadratic)...

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Founder TIGR/myocilin mutations for glaucoma in the Québec population

Mathieu Faucher, Jean-Louis Anctil, Marc-André Rodrigue, Annie Duchesne, Dan Bergeron, Pierre Blondeau, Gilles Côté, Stéphane Dubois, Josée Bergeron, Rose Arseneault, Jean Morissette and Vincent Raymond.

in Human Molecular Genetics

September 2002; p ublished online September 2002 .

Journal Article. Subjects: Genetics and Genomics. 10414 words.

Primary open-angle glaucoma (POAG) is a complex disorder characterized by a progressive and treatable degeneration of the optic nerve. TIGR/myocilin (MYOC) gene mutations are found in ∼4% of...

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Ataxia-Telangiectasia: Founder Effect Among North African Jews

Shlomit Gilad, Anat Bar-Shira, Reli Harnik, Dganit Shkedy, Yael Ziv, Rami Khosravi, Kevin Brown, Lina Vanagaite, Gang Xu, Moshe Frydman, Martin F. Lavin, David Hill, Danilo A. Tagle and Yosef Shiloh.

in Human Molecular Genetics

December 1996 .

Journal Article. Subjects: Genetics and Genomics. 3955 words.

The ATM gene is responsible for the autosomal recessive disorder ataxia-telangiectasia (A-T), characterized by cerebellar degeneration, immunodeficiency and cancer predisposition. A-T...

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Founder Effect in Spinal and Bulbar Muscular Atrophy (SBMA)

Fumiaki Tanaka, Manabu Doyu, Yasuhiro Ito, Michiyo Matsumoto, Terunori Mitsuma, Koji Abe, Masashi Aoki, Yasuto Itoyama, Kenneth H. Fischbeck and Gen Sobue.

in Human Molecular Genetics

September 1996 .

Journal Article. Subjects: Genetics and Genomics. 3229 words.

We analyzed the polymorphic (CAG)n and (GGC)n repeats of the androgen receptor gene in 113 unrelated X-linked spinal and bulbar muscular atrophy (SBMA) X chromosomes and 173 control X...

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Founder effects and the genetic structure of Coulter pine

FT Ledig.

in Journal of Heredity

July 2000; p ublished online July 2000 .

Journal Article. Subjects: Genetics and Genomics. 0 words.

Mean expected heterozygosity at 33 isozyme loci decreased with latitude from 0.193 near the southern extreme of Coulter pine's range to 0.107 at its northern extreme. This decrease was...

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Genome-Wide Search for Asthma Susceptibility Loci in a Founder Population

Carole Ober, Nancy J. Cox, Mark Abney, Anna Di Rienzo, Eric S. Lander, Benjarat Changyaleket, Heidi Gidley, Bradley Kurtz, June Lee, Marcus Nance, Anna Pettersson, Joyce Prescott, Anthony Richardson, Evelyn Schlenker, Eleanor Summerhill, Stephanie Willadsen and Rodney Parry.

in Human Molecular Genetics

September 1998; p ublished online September 1998 .

Journal Article. Subjects: Genetics and Genomics. 4932 words.

Founder populations offer many advantages for mapping genetic traits, particularly complex traits that are likely to be genetically heterogeneous. To identify genes that influence asthma...

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Willet M. Hays, Great Benefactor to Plant Breeding and the Founder of Our Association

A. F. Troyer and H. Stoehr.

in Journal of Heredity

November 2003; p ublished online November 2003 .

Journal Article. Subjects: Genetics and Genomics. 5538 words.

Willet M. Hays was a great benefactor to plant breeding and the founder of the American Genetic Association (AGA). We commemorate the AGA's centennial. We mined university archives, U.S....

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Tissue-specific responses to the LRPPRC founder mutation in French Canadian Leigh Syndrome

Florin Sasarman, Tamiko Nishimura, Hana Antonicka, Woranontee Weraarpachai and Eric A. Shoubridge.

in Human Molecular Genetics

January 2015; p ublished online September 2014 .

Journal Article. Subjects: Genetics and Genomics. 6024 words.

French Canadian Leigh Syndrome (LSFC) is an early-onset, progressive neurodegenerative disorder with a distinct pattern of tissue involvement. Most cases are caused by a founder missense...

Dissection of the HLA association with multiple sclerosis in the founder isolated population of Sardinia

Maria Giovanna Marrosu, Raffaele Murru, Maria Rita Murru, Gianna Costa, Patrizia Zavattari, Michael Whalen, Eleonora Cocco, Cristina Mancosu, Lucia Schirru, Elisabetta Solla, Elisabetta Fadda, Cristina Melis, Ilaria Porru, Marcella Rolesu and Francesco Cucca.

in Human Molecular Genetics

December 2001; p ublished online December 2001 .

Journal Article. Subjects: Genetics and Genomics. 7852 words.

Several studies have indicated that multiple sclerosis (MS) is associated and linked to the major histocompatibility complex (MHC)/human leukocyte antigen (HLA) region of chromosome 6p21.3,...

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Long-distance plant dispersal to North Atlantic islands: colonization routes and founder effect

Inger Greve Alsos, Dorothee Ehrich, Pernille Bronken Eidesen, Heidi Solstad, Kristine Bakke Westergaard, Peter Schönswetter, Andreas Tribsch, Siri Birkeland, Reidar Elven and Christian Brochmann.

in AoB PLANTS

P ublished online May 2015 .

Journal Article. Subjects: Ecology and Conservation; Genetics and Genomics; Plant Sciences and Forestry; Biological Sciences. 9189 words.

Long-distance dispersal (LDD) processes influence the founder effect on islands. We use genetic data for 25 Atlantic species and similarities among regional floras to analyse colonization,...

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Characterizing the multiplicity of HIV founder variants during sexual transmission among MSM

Antoine Chaillon, Sara Gianella, Susan J. Little, Gemma Caballero, Francis Barin, Sergei Kosakovsky Pond, Douglas D. Richman, Davey M. Smith and Sanjay R. Mehta.

in Virus Evolution

P ublished online June 2016 .

Journal Article. Subjects: Public Health and Epidemiology; Epidemiology; Evolutionary Biology; Genetics and Genomics; Microbiology. 3508 words.

Transmission of multiple founder variants has been associated with faster HIV disease progression. Many studies have attempted to determine the number of founder variants, mainly by...

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Duplication within the SEPT9 gene associated with a founder effect in North American families with hereditary neuralgic amyotrophy

Megan L. Landsverk, Elizabeth K. Ruzzo, Heather C. Mefford, Karen Buysse, Jillian G. Buchan, Evan E. Eichler, Elizabeth M. Petty, Esther A. Peterson, Dana M. Knutzen, Karen Barnett, Martin R. Farlow, Judy Caress, Gareth J. Parry, Dianna Quan, Kathy L. Gardner, Ming Hong, Zachary Simmons, Thomas D. Bird, Phillip F. Chance and Mark C. Hannibal.

in Human Molecular Genetics

April 2009; p ublished online January 2009 .

Journal Article. Subjects: Genetics and Genomics. 4740 words.

Hereditary neuralgic amyotrophy (HNA) is an autosomal dominant disorder associated with recurrent episodes of focal neuropathy primarily affecting the brachial plexus. Point mutations in...

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Recessive Amyotrophic Lateral Sclerosis Families with the D90A SOD1 Mutation Share a Common Founder: Evidence for a Linked Protective Factor

Ammar Al-Chalabi, Peter M. Andersen, Barry Chioza, Christopher Shaw, Pak C. Sham, Wim Robberecht, Gert Matthijs, William Camu, Stefan L. Marklund, Lars Forsgren, Guy Rouleau, Nigel G. Laing, P. V. Hurse, Teepu Siddique, P. Nigel Leigh and John F. Powell.

in Human Molecular Genetics

December 1998; p ublished online December 1998 .

Journal Article. Subjects: Genetics and Genomics. 3748 words.

Amyotrophic lateral sclerosis (ALS) is a progressive motor neurodegeneration resulting in paralysis and death from respiratory failure within 3–5 years. About 20% of familial cases are...

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Non-Founder Mutations in the MEFV Gene Establish This Gene as the Cause of Familial Mediterranean Fever (FMF)

Alain Bernot, Corinne da Silva, Jean-Louis Petit, Corinne Cruaud, Christophe Caloustian, Valérie Castet, Mehdi Ahmed-Arab, Christiane Dross, Madeleine Dupont, Daniel Cattan, Nizar Smaoui, Catherine Dodé, Christophe Pêcheux, Brigitte Nédelec, Jean Medaxian, Michel Rozenbaum, Itshak Rosner, Marc Delpech, Gilles Grateau, Jacques Demaille, Jean Weissenbach and Isabelle Touitou.

in Human Molecular Genetics

August 1998; p ublished online August 1998 .

Journal Article. Subjects: Genetics and Genomics. 4739 words.

Familial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by recurring attacks of fever and serositis. It affects primarily North African Jews, Armenians, Turks...

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Confirmation of the DRB1-DQB1 loci as the major component of IDDM1 in the isolated founder population of Sardinia

Patrizia Zavattari, Rosanna Lampis, Annapaola Mulargia, Miriam Loddo, Efisio Angius, John A. Todd and Francesco Cucca.

in Human Molecular Genetics

December 2000; p ublished online December 2000 .

Journal Article. Subjects: Genetics and Genomics. 4255 words.

There is considerable uncertainty and debate concerning the application of linkage disequilibrium (LD) mapping in common multifactorial diseases, including the choice of population and the...