Oxford Index Search Results

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fusion

Overview page. Subjects: Medicine and Health.

n. the joining together of two structures. For example, the surgical fusion of two or more vertebrae is performed to stabilize an unstable spine. Fusion of the epiphyses during...

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Nanobodies® Specific for Respiratory Syncytial Virus Fusion Protein Protect Against Infection by Inhibition of Fusion

Bert Schepens, Lorena Itatí Ibañez, Sarah De Baets, Anna Hultberg, Pieter Bogaert, Pieter De Bleser, Frederik Vervalle, Theo Verrips, José Melero, Wesly Vandevelde, Peter Vanlandschoot and Xavier Saelens.

in The Journal of Infectious Diseases

December 2011; p ublished online October 2011 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 5137 words.

(See the editorial commentary by Graham, on pages 1648–50.)

Despite the medical importance of respiratory syncytial virus (RSV) infections, there is no vaccine or therapeutic agent...

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Comparison Between Palivizumab Competitive Antibody (PCA) Assay Containing Pre-Fusion, Intermediate, and Post-Fusion Conformation of the Fusion (F) Protein of Respiratory Syncytial Virus (RSV)

Xunyan Ye.

in Open Forum Infectious Diseases

P ublished online October 2017 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 0 words.

Abstract

Background

Most RSV vaccines currently in clinical development include the F protein and exists in...

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Wound Infections Following Spinal Fusion with Posterior Segmental Spinal Instrumentation

Jean W. Perry, John Z. Montgomerie, Susan Swank, Donna S. Gilmore and Kim Maeder.

in Clinical Infectious Diseases

April 1997; p ublished online April 1997 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 0 words.

Twenty-three of 238 patients (9.7%) developed wound infections following segmental spinal instrumentation. When the infected group and a matched control group were compared, the infected...

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Fusion Inhibitory Lipopeptides Engineered for Prophylaxis of Nipah Virus in Primates

Cyrille Mathieu, Matteo Porotto, Tiago N Figueira, Branka Horvat and Anne Moscona.

in The Journal of Infectious Diseases

June 2018; p ublished online March 2018 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 5805 words.

Abstract

Background

The emerging zoonotic paramyxovirus Nipah virus (NiV) causes severe respiratory and...

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A mouse model of KIF5B-RET fusion-dependent lung tumorigenesis

Motonobu Saito, Teruhide Ishigame, Koji Tsuta, Kensuke Kumamoto, Toshio Imai and Takashi Kohno.

in Carcinogenesis

November 2014; p ublished online July 2014 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 2715 words.

Oncogenic fusion of the RET (rearranged during transfection) gene was recently identified as a novel driver gene aberration not only for the development of thyroid carcinoma but also of...

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209 Myeloid Sarcoma With CBFB-MYH11 Fusion (Inversion 16): A Clinicopathologic Analysis of 10 Cases

Kaari Reichard and Rhett Ketterling.

in American Journal of Clinical Pathology

January 2018; p ublished online January 2018 .

Journal Article. Subjects: Medical Skills; Pathology. 0 words.

Abstract

Introduction

Myeloid sarcoma without bone marrow (BM) involvement is a rare phenomenon. In the literature,...

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Specific depletion of autoreactive B lymphocytes by a recombinant fusion protein in vitro and in vivo

Marcel Zocher, Patrick A. Baeuerle, Torsten Dreier and Antonio Iglesias.

in International Immunology

July 2003; p ublished online July 2003 .

Journal Article. Subjects: Immunology; Biological Sciences. 6341 words.

Antigen‐specific B cells are key players in many autoimmune diseases through the production of autoreactive antibodies that can cause severe tissue damage and malfunction. We have designed...

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DNA vaccination with gp96–peptide fusion proteins induces protection against an intracellular bacterial pathogen

Ulrike K. Rapp and Stefan H. Kaufmann.

in International Immunology

April 2004; p ublished online April 2004 .

Journal Article. Subjects: Immunology; Biological Sciences. 6018 words.

Effective vaccination using in vitro peptide‐loaded heat‐shock proteins (HSP), tumor‐derived HSP and HSP fusion proteins has been shown in viral, parasite and tumor model systems. We...

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Targetable Gene Fusions Associate With the IDH Wild-Type Astrocytic Lineage in Adult Gliomas

Sherise D Ferguson, Shouhao Zhou, Jason T Huse, John F de Groot, Joanne Xiu, Deepa S Subramaniam, Shwetal Mehta, Zoran Gatalica, Jeffrey Swensen, Nader Sanai, David Spetzler and Amy B Heimberger.

in Journal of Neuropathology & Experimental Neurology

June 2018; p ublished online April 2018 .

Journal Article. Subjects: Neurology; Clinical Neuroscience; Pathology; Histopathology. 2933 words.

Abstract

Gene fusions involving oncogenes have been reported in gliomas and may serve as novel therapeutic targets. Using RNA-sequencing, we interrogated a...

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Structural and Functional Studies on the Marburg Virus GP2 Fusion Loop

Nina Liu, Yisong Tao, Michael D. Brenowitz, Mark E. Girvin and Jonathan R. Lai.

in The Journal of Infectious Diseases

October 2015; p ublished online September 2015 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 4771 words.

Marburg virus (MARV) and the ebolaviruses belong to the family Filoviridae (the members of which are filoviruses) that cause severe hemorrhagic fever. Infection requires fusion of the host...

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Risk Factors for Surgical Site Infections Following Spinal Fusion Procedures: A Case-Control Study

Shilpa B. Rao, Gustavo Vasquez, James Harrop, Mitchell Maltenfort, Natalie Stein, George Kaliyadan, Frank Klibert, Richard Epstein, Ashwini Sharan, Alexander Vaccaro and Phyllis Flomenberg.

in Clinical Infectious Diseases

October 2011; p ublished online October 2011 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 3823 words.

Background.  Spinal fusion procedures are associated with a significant rate of surgical site infection (SSI) (1%–12%). The goal of this study was...

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Immunological characterization of the sheep prion protein expressed as fusion proteins in Escherichia coli

Thierry G.M. Baron, Dominique Betemps, Martin H. Groschup and Jean-Yves Madec.

in FEMS Immunology & Medical Microbiology

September 1999; p ublished online January 2006 .

Journal Article. Subjects: Medical Microbiology and Virology; Biotechnology; Genetics and Genomics; Microbiology; Molecular and Cell Biology. 2631 words.

Abstract

The prion protein (PrP) from sheep was produced in large quantities of entire protein in Escherichia coli after fusion with a carboxy-terminal...

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Enfuvirtide (T-20): A Novel Human Immunodeficiency Virus Type 1 Fusion Inhibitor

Saravolatz Louis D., Joseph S. Cervia and Miriam A. Smith.

in Clinical Infectious Diseases

October 2003; p ublished online October 2003 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 3260 words.

The development of highly active antiretroviral therapy has improved life expectancy and reduced progression to acquired immunodeficiency syndrome in human immunodeficiency virus...

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Surfactant Protein A Binds to the Fusion Glycoprotein of Respiratory Syncytial Virus and Neutralizes Virion Infectivity

Reena Ghildyal, Carol Hartley, Annalisa Varrasso, Jayesh Meanger, Dennis R. Voelker, E. Margot Anders and John Mills.

in The Journal of Infectious Diseases

December 1999; p ublished online December 1999 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 2567 words.

Collectins are a family of calcium-dependent collagenous lectins that appear to be important in innate host defense. We investigated the ability of three human collectins, namely, lung...

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Human Metapneumovirus Reinfection among Children in Thailand Determined by ELISA Using Purified Soluble Fusion Protein

Julie A. Pavlin, Andrew C. Hickey, Nancy Ulbrandt, Yee-Peng Chan, Timothy P. Endy, Marina S. Boukhvalova, Supamit Chunsuttiwat, Ananda Nisalak, Daniel H. Libraty, Sharone Green, Alan L. Rothman, Francis A. Ennis, Richard Jarman, Robert V. Gibbons and Christopher C. Broder.

in The Journal of Infectious Diseases

September 2008; p ublished online September 2008 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 4883 words.

Background. Human metapneumovirus (hMPV) is a newly discovered paramyxovirus that causes acute respiratory illness. Despite apparent near-universal...

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Mouse models for ROS1-fusion-positive lung cancers and their application to the analysis of multikinase inhibitor efficiency

Maki Inoue, Hideaki Toki, Junko Matsui, Yuki Togashi, Akito Dobashi, Ryutaro Fukumura, Yoichi Gondo, Osamu Minowa, Norio Tanaka, Seiichi Mori, Kengo Takeuchi and Tetsuo Noda.

in Carcinogenesis

May 2016; p ublished online March 2016 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 5978 words.

ROS1-fusion genes, resulting from chromosomal rearrangement, have been reported in 1–2% of human non-small cell lung cancer cases. More than 10 distinct ROS1-fusion genes,...

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Radiation-induced homotypic cell fusions of innately resistant glioblastoma cells mediate their sustained survival and recurrence

Ekjot Kaur, Jacinth Rajendra, Shailesh Jadhav, Epari Shridhar, Jayant Sastri Goda, Aliasgar Moiyadi and Shilpee Dutt.

in Carcinogenesis

June 2015; p ublished online April 2015 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 6898 words.

Understanding of molecular events underlying resistance and relapse in glioblastoma (GBM) is hampered due to lack of accessibility to resistant cells from patients undergone therapy....

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B7.2-Ig fusion proteins enhance IL-4-dependent differentiation of tumor-sensitized CD8+ cytotoxic T lymphocyte precursors

Shin-ichiro Hiraoka, Noritami Takeuchi, Yang Bian, Hirokazu Nakahara, Mikihiko Kogo, Kyriaki Dunussi-Joannopoulos, Stanley Wolf, Shiro Ono and Hiromi Fujiwara.

in International Immunology

August 2005; p ublished online July 2005 .

Journal Article. Subjects: Immunology; Biological Sciences. 6833 words.

The B7/CD28 co-stimulatory pathway plays a critical role in T cell activation and differentiation. Our previous study demonstrated that administration of B7.2-Ig fusion proteins to...

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MHC class II loading of high or low affinity peptides directed by Ii/peptide fusion constructs: implications for T cell activation

Tone F. Gregers, Burkhard Fleckenstein, Frode Vartdal, Peter Roepstorff, Oddmund Bakke and Inger Sandlie.

in International Immunology

November 2003; p ublished online November 2003 .

Journal Article. Subjects: Immunology; Biological Sciences. 6748 words.

CD4+ T cells recognize peptides presented on the cell surface of antigen presenting cells in the MHC class II context. The biosynthesis and transport of MHC class II molecules depend on the...

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Activation of T cells by the ragged tail of MHC class II-presented peptides of the measles virus fusion protein

Claude P. Muller, Wim Ammerlaan, Burkhard Fleckenstein, Steffen Krauss, Hubert Kalbacher, Francois Schneider, Günther Jung and Karl-Heinz Wiesmüller.

in International Immunology

April 1996 .

Journal Article. Subjects: Immunology; Biological Sciences. 0 words.

The efficient and sustained immune response of an antigen requires T cell epitopes, capable of inducing a long lasting T cell memory. To detect T cell epitopes of the measles virus fusion...

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