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random vector

Overview page. Subjects: Mathematics.

An ordered set of n random variables, often representing the outcomes of a repeated experiment. For example, if I throw a die four times the outcome of the experiment could be described by...

See overview in Oxford Index

First-in-Human Randomized, Controlled Trial of Mosaic HIV-1 Immunogens Delivered via a Modified Vaccinia Ankara Vector

Lindsey R Baden, Stephen R Walsh, Michael S Seaman, Yehuda Z Cohen, Jennifer A Johnson, J Humberto Licona, Rachel D Filter, Jane A Kleinjan, Jon A Gothing, Julia Jennings, Lauren Peter, Joseph Nkolola, Peter Abbink, Erica N Borducchi, Marinela Kirilova, Kathryn E Stephenson, Poonam Pegu, Michael A Eller, Hung V Trinh, Mangala Rao, Julie A Ake, Michal Sarnecki, Steven Nijs, Katleen Callewaert, Hanneke Schuitemaker, Jenny Hendriks, Maria G Pau, Frank Tomaka, Bette T Korber, Galit Alter, Raphael Dolin, Patricia L Earl, Bernard Moss, Nelson L Michael, Merlin L Robb and Dan H Barouch.

in The Journal of Infectious Diseases

July 2018; p ublished online April 2018 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 5867 words.

Abstract

Background

Mosaic immunogens are bioinformatically engineered human immunodeficiency virus type 1 (HIV-1)...

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An Ad5-Vectored HIV-1 Vaccine Elicits Cell-mediated Immunity but does not Affect Disease Progression in HIV-1–infected Male Subjects: Results From a Randomized Placebo-Controlled Trial (The Step Study)

D. W. Fitzgerald, H. Janes, M. Robertson, R. Coombs, I. Frank, P. Gilbert, M. Loufty, D. Mehrotra and A. Duerr.

in The Journal of Infectious Diseases

March 2011; p ublished online March 2011 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 4608 words.

(See the editorial commentary by Altfeld and Goulder, on pages 753–5.)

Background . The Step study was a randomized trial to determine...

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Selection of Neighborhood Controls for a Population-Based Lyme Disease Case-Control Study by Using a Commercial Marketing Database

Neeta P. Connally, Kimberly Yousey-Hindes and James Meek.

in American Journal of Epidemiology

July 2013; p ublished online May 2013 .

Journal Article. Subjects: Public Health and Epidemiology. 2596 words.

The selection of controls is an important methodological consideration for case-control studies. Neighborhood-matched control selection is particularly crucial for studies of vector-borne...

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Do malaria preventive interventions reach the poor? Socioeconomic inequities in expenditure on and use of mosquito control tools in Sudan

Obinna Onwujekwe, El-Fatih Malik, Sara Hassan Mustafa and Abraham Mnzavaa.

in Health Policy and Planning

January 2006; p ublished online November 2005 .

Journal Article. Subjects: Public Health and Epidemiology. 5066 words.

Objectives: To determine levels of socioeconomic inequities in the prevention of malaria, and to examine the implications of the findings for improving the equitable control of...

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Risk factors of visceral leishmaniasis in East Africa: a case-control study in Pokot territory of Kenya and Uganda

Jan H Kolaczinski, Richard Reithinger, Dagemlidet T Worku, Andrew Ocheng, John Kasimiro, Narcis Kabatereine and Simon Brooker.

in International Journal of Epidemiology

April 2008; p ublished online January 2008 .

Journal Article. Subjects: Public Health and Epidemiology. 4565 words.

Background In East Africa, visceral leishmaniasis (VL) is endemic in parts of Sudan, Ethiopia, Somalia, Kenya and Uganda. It is caused by Leishmania donovani and transmitted by...

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Profile: The Rusinga Health and Demographic Surveillance System, Western Kenya

Tobias Homan, Aurelio di Pasquale, Kelvin Onoka, Ibrahim Kiche, Alexandra Hiscox, Collins Mweresa, Wolfgang R Mukabana, Daniel Masiga, Willem Takken and Nicolas Maire.

in International Journal of Epidemiology

June 2016; p ublished online May 2016 .

Journal Article. Subjects: Public Health and Epidemiology. 4764 words.

The health and demographic surveillance system on Rusinga Island, Western Kenya, was initiated in 2012 to facilitate a malaria intervention trial: the SolarMal project. The project aims to...

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Use of health care among febrile children from urban poor households in Senegal: does the neighbourhood have an impact?

Georges Karna Kone, Richard Lalou, Martine Audibert, Hervé Lafarge, Stéphanie Dos Santos, Alphousseyni Ndonky and Jean-Yves Le Hesran.

in Health Policy and Planning

December 2015; p ublished online March 2015 .

Journal Article. Subjects: Public Health and Epidemiology. 8250 words.

Urban malaria is considered a major public health problem in Africa. The malaria vector is well adapted in urban settings and autochthonous malaria has increased. Antimalarial treatments...

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Improved dengue fever prevention through innovative intervention methods in the city of Salto, Uruguay

César Basso, Elsa García da Rosa, Sonnia Romero, Cristina González, Rosario Lairihoy, Ingrid Roche, Ruben M. Caffera, Ricardo da Rosa, Marisel Calfani, Eduardo Alfonso-Sierra, Max Petzold, Axel Kroeger and Johannes Sommerfeld.

in Transactions of The Royal Society of Tropical Medicine and Hygiene

February 2015; p ublished online January 2015 .

Journal Article. Subjects: Public Health and Epidemiology; Clinical Medicine; Infectious Diseases; Medical Microbiology and Virology; Immunology. 6154 words.

Background

Uruguay is located at the southern border of Aedes aegypti distribution on the South American sub-continent. The reported dengue cases in the...

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Entomological impact and social participation in dengue control: a cluster randomized trial in Fortaleza, Brazil

Andrea Caprara, José Wellington De Oliveira Lima, Ana Carolina Rocha Peixoto, Cyntia Monteiro Vasconcelos Motta, Joana Mary Soares Nobre, Johannes Sommerfeld and Axel Kroeger.

in Transactions of The Royal Society of Tropical Medicine and Hygiene

February 2015; p ublished online January 2015 .

Journal Article. Subjects: Public Health and Epidemiology; Clinical Medicine; Infectious Diseases; Medical Microbiology and Virology; Immunology. 4197 words.

Background

This study intended to implement a novel intervention strategy, in Brazil, using an ecohealth approach and analyse its effectiveness and costs in...

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Development of a community-based intervention for the control of Chagas disease based on peridomestic animal management: an eco-bio-social perspective

Sandra M. De Urioste-Stone, Pamela M. Pennington, Elizabeth Pellecer, Teresa M. Aguilar, Gabriela Samayoa, Hugo D. Perdomo, Hugo Enríquez and José G. Juárez.

in Transactions of The Royal Society of Tropical Medicine and Hygiene

February 2015; p ublished online January 2015 .

Journal Article. Subjects: Public Health and Epidemiology; Clinical Medicine; Infectious Diseases; Medical Microbiology and Virology; Immunology. 4711 words.

Background

Integrated vector management strategies depend on local eco-bio-social conditions, community participation, political will and inter-sectorial...

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Effectiveness and feasibility of long-lasting insecticide-treated curtains and water container covers for dengue vector control in Colombia: a cluster randomised trial

Juliana Quintero, Tatiana García-Betancourt, Sebastian Cortés, Diana García, Lucas Alcalá, Catalina González-Uribe, Helena Brochero and Gabriel Carrasquilla.

in Transactions of The Royal Society of Tropical Medicine and Hygiene

February 2015; p ublished online January 2015 .

Journal Article. Subjects: Public Health and Epidemiology; Clinical Medicine; Infectious Diseases; Medical Microbiology and Virology; Immunology. 5096 words.

Background

Long-lasting insecticide-treated net (LLIN) window and door curtains alone or in combination with LLIN water container covers were analysed...

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Vaccination With Heterologous HIV-1 Envelope Sequences and Heterologous Adenovirus Vectors Increases T-Cell Responses to Conserved Regions: HVTN 083

Stephen R. Walsh, Zoe Moodie, Andrew J. Fiore-Gartland, Cecilia Morgan, Marissa B. Wilck, Scott M. Hammer, Susan P. Buchbinder, Spyros A. Kalams, Paul A. Goepfert, Mark J. Mulligan, Michael C. Keefer, Lindsey R. Baden, Edith M. Swann, Shannon Grant, Hasan Ahmed, Fusheng Li, Tomer Hertz, Steven G. Self, David Friedrich, Nicole Frahm, Hua-Xin Liao, David C. Montefiori, Georgia D. Tomaras, M. Juliana McElrath, John Hural, Barney S. Graham and Xia Jin.

in The Journal of Infectious Diseases

February 2016; p ublished online October 2015 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 5991 words.

Background.  Increasing the breadth of human immunodeficiency virus type 1 (HIV-1) vaccine-elicited immune responses or targeting conserved regions...

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Induction of HIV-1-specific mucosal immune responses following intramuscular recombinant adenovirus serotype 26 HIV-1 vaccination of humans

Lindsey R. Baden, Jinyan Liu, Hualin Li, Jennifer A. Johnson, Stephen R. Walsh, Jane A. Kleinjan, Brian A. Engelson, Lauren Peter, Peter Abbink, Danny A. Milner, Kevin L. Golden, Kyle L. Viani, Matthew D. Stachler, Benjamin J. Chen, Maria G. Pau, Mo Weijten, Brittany R. Carey, Caroline A. Miller, Edith M. Swann, Mark Wolff, Hayley Loblein, Michael S. Seaman, Raphael Dolin and Dan H. Barouch.

in The Journal of Infectious Diseases

August 2014; p ublished online August 2014 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 0 words.

Background.  Defining mucosal immune responses and inflammation to candidate HIV-1 vaccines represent a current research priority for the HIV-1...

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First-in-Human Evaluation of the Safety and Immunogenicity of a Recombinant Adenovirus Serotype 26 HIV-1 Env Vaccine (IPCAVD 001)

Lindsey R. Baden, Stephen R. Walsh, Michael S. Seaman, Robert P. Tucker, Kathleen H. Krause, Alka Patel, Jennifer A. Johnson, Jane Kleinjan, Katherine E. Yanosick, James Perry, Elise Zablowsky, Peter Abbink, Lauren Peter, M. Justin Iampietro, Ann Cheung, Maria G. Pau, Mo Weijtens, Jaap Goudsmit, Edith Swann, Mark Wolff, Hayley Loblein, Raphael Dolin and Dan H. Barouch.

in The Journal of Infectious Diseases

January 2013; p ublished online November 2012 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 3640 words.

Background.  We report the first-in-human safety and immunogenicity assessment of a prototype Ad26 vector-based human immunodeficiency virus (HIV)...

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Reservoir Targeted Vaccine Against Borrelia burgdorferi: A New Strategy to Prevent Lyme Disease Transmission

Luciana Meirelles Richer, Dustin Brisson, Rita Melo, Richard S. Ostfeld, Nordin Zeidner and Maria Gomes-Solecki.

in The Journal of Infectious Diseases

June 2014; p ublished online February 2014 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 5367 words.

A high prevalence of infection with Borrelia burgdorferi in ixodid ticks is correlated with a high incidence of Lyme disease. The transmission of B. burgdorferi to humans can be disrupted...

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Correlation between positive serology for Plasmodium vivax-like/Plasmodium simiovale malaria parasites in the human and anopheline populations in the State of Acre, Brazil

Mauro Toledo Marrelli, Maria Stela Branquinho, Erika Hellena Esther Hoffmann, Carmen Beatriz Taipe-Lagos, Delsio Natal and Judith Kardos Kloetzel.

in Transactions of The Royal Society of Tropical Medicine and Hygiene

April 1998; p ublished online April 1998 .

Journal Article. Subjects: Clinical Medicine; Infectious Diseases; Immunology; Medical Microbiology and Virology; Public Health and Epidemiology. 0 words.

Antibodies against the Plasmodium vivax-like/P. simiovale malaria parasite circumsporozoite repeat peptide (APGANQEGGAA)3 were determined by enzyme-linked immunosorbent assay (ELISA) in 120...

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Comparison of Systemic and Mucosal Delivery of 2 Canarypox Virus Vaccines Expressing either HIV-1 Genes or the Gene for Rabies Virus G Protein

Peter F. Wright, Jiri Mestecky, M. Juliana McElrath, Michael C. Keefer, Geoffrey J. Gorse, Paul A. Goepfert, Zina Moldoveanu, David Schwartz, Paul W. Spearman, Raphaelle El Habib, Michele D. Spring, Yuwei Zhu, Carol Smith, Jorge Flores and Kent J. Weinhold.

in The Journal of Infectious Diseases

April 2004; p ublished online April 2004 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 5576 words.

Background. Since the primary routes of human immunodeficiency type 1 (HIV-1) infection are across mucosal barriers, a randomized trial of...

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Immunogenicity of a Recombinant Human Immunodeficiency Virus (HIV)–Canarypox Vaccine in HIV-Seronegative Ugandan Volunteers: Results of the HIV Network for Prevention Trials 007 Vaccine Study

H Cao, P Kaleebu, D Hom, J Flores, D Agrawal, N Jones, J Serwanga, M Okello, C Walker, H Sheppard, R El-Habib, M Klein, E Mbidde, P Mugyenyi, B Walker and J Ellner.

in The Journal of Infectious Diseases

March 2003; p ublished online March 2003 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 4859 words.

In the first preventative human immunodeficiency virus (HIV) vaccine study to be carried out in Africa, 40 HIV-seronegative Ugandan volunteers were randomly assigned to receive a canarypox...

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Phase 1 Safety and Immunogenicity Evaluation of a Multiclade HIV‐1 Candidate Vaccine Delivered by a Replication‐Defective Recombinant Adenovirus Vector

Andrew T.  Catanzaro, Richard A.  Koup, Mario  Roederer, Robert T.  Bailer, Mary E.  Enama, Zoe  Moodie, Lin  Gu, Julie E.  Martin, Laura  Novik, Bimal K.  Chakrabarti, Bryan T.  Butman, Jason G. D.  Gall, C. Richter  King, Charla A.  Andrews, Rebecca  Sheets, Phillip L.  Gomez, John R.  Mascola and Gary J.  Nabel.

in The Journal of Infectious Diseases

December 2006; p ublished online December 2006 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 6452 words.

Background. The development of an effective human immunodeficiency virus (HIV) vaccine is a high global priority. Here, we report the safety, tolerability, and immunogenicity...

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First-in-Human Evaluation of a Hexon Chimeric Adenovirus Vector Expressing HIV-1 Env (IPCAVD 002)

Lindsey R. Baden, Stephen R. Walsh, Michael S. Seaman, Jennifer A. Johnson, Robert P. Tucker, Jane A. Kleinjan, Jon A. Gothing, Brian A. Engelson, Brittany R. Carey, Avinash Oza, Shringkhala Bajimaya, Lauren Peter, Chelsea Bleckwehl, Peter Abbink, Maria G. Pau, Mo Weijtens, Meghan Kunchai, Edith M. Swann, Mark Wolff, Raphael Dolin and Dan H. Barouch.

in The Journal of Infectious Diseases

October 2014; p ublished online April 2014 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 4831 words.

Background.  We report the first-in-human safety and immunogenicity assessment of a prototype hexon chimeric adenovirus (Ad) serotype 5 (Ad5) vector...

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