Oxford Index Search Results

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sensitive

Overview page. Subjects: Medicine and Health.

adj. possessing the ability to respond to a stimulus. The cells of the retina, for example, are sensitive to the stimulus of light and respond by sending nerve impulses to the...

See overview in Oxford Index

Theoretical context-sensitive elimination times for inhalation anaesthetics

G. Lockwood.

in BJA: British Journal of Anaesthesia

May 2010; p ublished online March 2010 .

Journal Article. Subjects: Anaesthetics. 4664 words.

Background

Context-sensitive times to 50%, 80%, and 90% elimination from the brain have been calculated for volatile anaesthetics. This does not represent...

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Clinical evaluation of algorithms for context-sensitive physiological monitoring in children

M. Dosani, J. Lim, P. Yang, C. Brouse, J. Daniels, G. Dumont and J. M. Ansermino.

in BJA: British Journal of Anaesthesia

May 2009; p ublished online March 2009 .

Journal Article. Subjects: Anaesthetics. 3318 words.

Background

Subtle changes in monitored physiological signals might be used to guide clinical actions and give early warning of potential adverse events....

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Nicotinic receptor-evoked hippocampal norepinephrine release is highly sensitive to inhibition by isoflurane

R. I. Westphalen, R. S. Gomez and H. C. Hemmings.

in BJA: British Journal of Anaesthesia

March 2009; p ublished online February 2009 .

Journal Article. Subjects: Anaesthetics. 2964 words.

Background

Inhaled anaesthetics (IAs) produce multiple dose-dependent behavioural effects including amnesia, hypnosis, and immobility in response to painful...

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Thiopental and propofol impair relaxation produced by ATP-sensitive potassium channel openers in the rat aorta.

H Kinoshita, K Ishida and T Ishikawa.

in BJA: British Journal of Anaesthesia

November 1998; p ublished online November 1998 .

Journal Article. Subjects: Anaesthetics. 0 words.

ATP-sensitive potassium channel openers are used as vasodilators in the treatment of cardiovascular disorders. The effects of i.v. anaesthetics on arterial relaxation induced by...

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High-sensitive cardiac troponin T measurements in prediction of non-cardiac complications after major abdominal surgery

P. G. Noordzij, O. van Geffen, I. M. Dijkstra, D. Boerma, A. J. Meinders, T. C. D. Rettig, F. D. Eefting, D. van Loon, E. M. W. van de Garde and E. P. A. van Dongen.

Edited by J. P. Thompson.

in BJA: British Journal of Anaesthesia

June 2015; p ublished online March 2015 .

Journal Article. Subjects: Anaesthetics. 6236 words.

Background

Postoperative non-cardiac complication rates are as high as 11–28% after high-risk abdominal procedures. Emerging evidence indicates that...

I.v. anaesthetic agents do not interact with the verapamil binding site on L-type voltage-sensitive Ca2+ channels.

K Hirota and D G Lambert.

in BJA: British Journal of Anaesthesia

January 1996 .

Journal Article. Subjects: Anaesthetics. 0 words.

In this study we have examined if the i.v. anaesthetic agents thiopentone, pentobarbitone, ketamine, etomidate, propofol and alphaxalone interact with the verapamil binding site on L-type...

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Liver function test abnormalities after traumatic brain injury: is hepato-biliary ultrasound a sensitive diagnostic tool?

F. Sanfilippo, T. Veenith, C. Santonocito, C. S. Vrettou and B. F. Matta.

Edited by A. R. Absalom.

in BJA: British Journal of Anaesthesia

February 2014; p ublished online September 2013 .

Journal Article. Subjects: Anaesthetics. 3556 words.

Background

This study was to evaluate the usefulness of hepato-biliary ultrasound (HBUS) for the investigation of isolated liver function tests (LFTs)...

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I.v. anaesthetic agents inhibit dihydropyridine binding to L-type voltage-sensitive Ca2+ channels in rat cerebrocortical membranes.

K Hirota and D G Lambert.

in BJA: British Journal of Anaesthesia

August 1996 .

Journal Article. Subjects: Anaesthetics. 0 words.

Previous studies have implicated the neuronal L-type voltage-sensitive Ca2+ channel (VSCC) as a target site for i.v. anaesthetic agents. It is unclear if these agents interact with the...

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Reflex pupillary dilatation in response to skin incision and alfentanil in children anaesthetized with sevoflurane: a more sensitive measure of noxious stimulation than the commonly used variables

I. Constant, M.-C. Nghe, L. Boudet, J. Berniere, S. Schrayer, R. Seeman and I. Murat.

in BJA: British Journal of Anaesthesia

May 2006; p ublished online March 2006 .

Journal Article. Subjects: Anaesthetics. 2488 words.

Background. Estimation of analgesia in anaesthetized children is often imprecise, and consequently, anaesthesiologists commonly evaluate children's response to surgical...

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Inhibitory effects of intravenous anaesthetic agents on K+‐evoked norepinephrine and dopamine release from rat striatal slices: possible involvement of P/Q‐type voltage‐sensitive Ca2+ channels

K. Hirota, M. Kudo, T. Kudo, A. Matsuki and D. G. Lambert.

in BJA: British Journal of Anaesthesia

December 2000; p ublished online December 2000 .

Journal Article. Subjects: Anaesthetics. 3633 words.

The role of the voltage‐sensitive Ca2+ channel (VSCC) as a target for anaesthetic action remains controversial. In this study we characterized the VSCC subtypes involved in K+‐evoked...

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Dose‐dependent prophylactic effect of nicorandil, an ATP‐sensitive potassium channel opener, on intra‐operative myocardial ischaemia in patients undergoing major abdominal surgery

T. Kaneko, Y. Saito, Y. Hikawa, K. Yasuda and K. Makita.

in BJA: British Journal of Anaesthesia

March 2001; p ublished online March 2001 .

Journal Article. Subjects: Anaesthetics. 3226 words.

Nicorandil, a nicotinamide nitrate derivative, relaxes vascular smooth muscle and reduces cardiac muscle contractility by increasing membrane potassium conductance, probably by activating...

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Voltage-sensitive Ca2+ channels and anaesthesia.

K Hirota and D G Lambert.

in BJA: British Journal of Anaesthesia

March 1996 .

Journal Article. Subjects: Anaesthetics. 0 words.

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Chronic post-surgical pain

Dr Prit Singh and Dr Joanna Renée.

in Oxford Case Histories in Anaesthesia

December 2014; p ublished online March 2015 .

Chapter. Subjects: Anaesthetics. 2161 words.

An anxious 32-year-old female has presented to the chronic pain clinic with constant, severe pain of her anterior chest wall and axilla. She underwent a mastectomy and an axillary node...

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Predictive value of urine interleukin-18 in the evolution and outcome of acute kidney injury in critically ill adult patients

S. Nisula, R. Yang, M. Poukkanen, S. T. Vaara, K. M. Kaukonen, M. Tallgren, M. Haapio, J. Tenhunen, A. M. Korhonen and V. Pettilä.

Edited by J. P. Thompson.

in BJA: British Journal of Anaesthesia

March 2015; p ublished online December 2014 .

Journal Article. Subjects: Anaesthetics. 4439 words.

Background

Interleukin-18 (IL-18) is a pro-inflammatory protein, which mediates ischaemic tubular injury, and has been suggested to be a sensitive and...

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Microalbuminuria following anaphylaxis with general anaesthesia

P. R. Wood, P. Gosling and M. C. Cook.

in BJA: British Journal of Anaesthesia

June 2000; p ublished online June 2000 .

Journal Article. Subjects: Anaesthetics. 0 words.

Microalbuminuria is increasingly recognized as a marker of pathologies that cause acute systemic capillary leak. We report a case of an anaphylactic reaction to general anaesthesia involving...

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Halothane and desflurane requirements in alcohol‐tolerant and ‐nontolerant rats

L. L. Firestone, E. R. Korpi, L. Niemi, P. H. Rosenberg, G. E. Homanics and J. J. Quinlan.

in BJA: British Journal of Anaesthesia

November 2000; p ublished online November 2000 .

Journal Article. Subjects: Anaesthetics. 3655 words.

On the basis of data implicating GABAA receptors in the effects of volatile general anaesthetics, we hypothesized that alcohol‐, barbiturate‐, and benzodiazepine‐sensitive...

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Flow-by induced hypoventilation in high spinal cord lesions—report of two cases

S. Kannan, N. Sherwood and A. Armfield.

in BJA: British Journal of Anaesthesia

September 2002; p ublished online September 2002 .

Journal Article. Subjects: Anaesthetics. 0 words.

Flow triggering in ventilators is an alternative to pressure triggering. Differences between these two trigger mechanisms may not be clinically significant in most patients. We report two...

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An fMRI-Based Neurologic Signature of Physical Pain

Edited by Anita Gupta, Elena N. Gutman and Michael E. Hochman.

in 50 Studies Every Anesthesiologist Should Know

December 2018; p ublished online January 2019 .

Chapter. Subjects: Anaesthetics. 905 words.

This case focuses on fMRI-based neurologic signatures of physical pain by asking the question: Can functional magnetic resonance imaging (fMRI) be used to identify sensitive and specific...

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Blood propofol concentration and psychomotor effects on driving skills

S. A. Grant, J. Murdoch, K. Millar and G. N. C. Kenny.

in BJA: British Journal of Anaesthesia

September 2000; p ublished online September 2000 .

Journal Article. Subjects: Anaesthetics. 2487 words.

We studied psychomotor performance in 10 healthy volunteers during recovery after a target‐controlled infusion of propofol. Choice reaction time, dual task tracking with secondary reaction...

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Influence of dose of domperidone on the acute ventilatory response to hypoxia in humans.

T S Walsh, I T Foo, G B Drummond and P M Warren.

in BJA: British Journal of Anaesthesia

January 1998; p ublished online January 1998 .

Journal Article. Subjects: Anaesthetics. 0 words.

We have studied the ventilatory responses to acute isocapnic hypoxia (SpO2 78.8 (SD 1.4)% for 10 min) in 10 male volunteers given three different doses of oral domperidone: placebo,...

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