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sensitive

Overview page. Subjects: Medicine and Health.

adj. possessing the ability to respond to a stimulus. The cells of the retina, for example, are sensitive to the stimulus of light and respond by sending nerve impulses to the...

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Return of Widespread Chloroquine-Sensitive Plasmodium falciparum to Malawi

Anne E. P. Frosch, Miriam K. Laufer, Don P. Mathanga, Shannon Takala-Harrison, Jacek Skarbinski, Cassidy W. Claassen, Fraction K. Dzinjalamala and Christopher V. Plowe.

in The Journal of Infectious Diseases

October 2014; p ublished online April 2014 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 2305 words.

Background.  The return of chloroquine-sensitive Plasmodium falciparum to the limited area of Blantyre, Malawi, has been well demonstrated in...

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Early lymphoid progenitors in mouse and man are highly sensitive to glucocorticoids

Hideya Igarashi, Kay L. Medina, Takafumi Yokota, Maria Isabel D. Rossi, Nobuo Sakaguchi, Philip C. Comp and Paul W. Kincade.

in International Immunology

May 2005; p ublished online March 2005 .

Journal Article. Subjects: Immunology; Biological Sciences. 7645 words.

Glucocorticoids are extensively used in anti-inflammatory therapy and may contribute to the normal regulation of lymphopoiesis. This study utilized new information about the early stages of...

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The common occurrence of ceftriaxone-resistant methicillin sensitive Staphylococcus aureus at a community teaching hospital

Aaron Pickering, Rahman Hariri, Lee H. Harrison, Jane W. Marsh, Amatullah Tasneem, Henry Freedy, Laura Wilson and Hector Bonilla.

in Clinical Infectious Diseases

January 2014; p ublished online March 2014 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 0 words.

Although the rate of ceftriaxone resistance in methicillin-sensitive Staphylococcus aureus (MSSA) is reported at approximately 3% in the literature, findings at our institution suggest it...

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Sodium stibogluconate-sensitive visceral leishmaniasis in the non-endemic hilly region of Uttarakhand, India

S.K. Verma, Sohaib Ahmad, Nadia Shirazi, Anuradha Kusum, R.M. Kaushik and S.P. Barthwal.

in Transactions of The Royal Society of Tropical Medicine and Hygiene

July 2007; p ublished online July 2007 .

Journal Article. Subjects: Clinical Medicine; Infectious Diseases; Immunology; Medical Microbiology and Virology; Public Health and Epidemiology. 854 words.

Summary

Although visceral leishmaniasis (VL) is endemic in various parts of India, mainly Bihar, West Bengal and Orissa, and neighbouring countries such as...

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Reassortment between Amantadine-Resistant and -Sensitive H1N1 Influenza A Viruses Generated an Amantadine-Sensitive Virus during the 2007–2008 Season

Yuki Furuse, Akira Suzuki, Midori Shimizu, Makiko Kishi, Rumi Sawayama, Mariko Saito, Naoko Fuji, Nao Nukiwa and Hitoshi Oshitani.

in The Journal of Infectious Diseases

December 2009; p ublished online December 2009 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 2767 words.

The frequency of the amantadine-resistant H1N1 influenza A virus has been increasing since the 2005–2006 season. It is unclear whether reassortment was involved in this trend. Here, we show...

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Reemergence of Chloroquine-Sensitive Plasmodium falciparum Malaria after Cessation of Chloroquine Use in Malawi

James G Kublin, Joseph F Cortese, Eric Mbindo Njunju, Rabia A G. Mukadam, Jack J Wirima, Peter N Kazembe, Abdoulaye A Djimdé, Bourema Kouriba, Terrie E Taylor and Christopher V Plowe.

in The Journal of Infectious Diseases

June 2003; p ublished online June 2003 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 4365 words.

In 1993, Malawi became the first African country to replace chloroquine with sulfadoxine-pyrimethamine nationwide in response to high rates of chloroquine-resistant falciparum malaria. To...

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Improving Clinical Outcomes in Patients With Methicillin-Sensitive Staphylococcus aureus Bacteremia and Reported Penicillin Allergy

Kimberly G. Blumenthal, Robert A. Parker, Erica S. Shenoy and Rochelle P. Walensky.

in Clinical Infectious Diseases

September 2015; p ublished online May 2015 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 5813 words.

Background.  Methicillin-sensitive Staphylococcus aureus (MSSA) bacteremia is a morbid infection. First-line MSSA therapies (nafcillin, oxacillin,...

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Nanoparticle-based immunoassays for sensitive and early detection of HIV-1 capsid (p24) antigen

Shixing Tang and Indira Hewlett.

in The Journal of Infectious Diseases

April 2010; p ublished online April 2010 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 3278 words.

We evaluated the feasibility of using nanoparticle (NP)-based assays for improving detection sensitivity of human immunodeficiency virus type 1 (HIV-1) p24 antigen. One assay that was...

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Sensitive Detection Assays for Influenza RNA Do Not Reveal Viremia in US Blood Donors

Susan L. Stramer, Cynthia Collins, Thomas Nugent, Xue Wang, Meghan Fuschino, John W. Heitman, Jacqueline Law, David E. Krysztof, Nancy Kiely, Deborah Todd, Nicolaas M. J. Vermeulen, Karen Harrington, Hany Kamel, David J. Kelvin, Michael P. Busch, Kirsten St. George, Indira K. Hewlett, Jeffrey M. Linnen and Philip J. Norris.

in The Journal of Infectious Diseases

March 2012; p ublished online January 2012 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 4907 words.

(See the article by Delwart et al, on pages 875–85, and see the editorial commentary by Katz, on pages 867–9.)

Background.  There have been...

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Redox-sensitive events in Fas-induced apoptosis in human NK cells include ceramide generation and protein tyrosine dephosphorylation.

K Furuke and E T Bloom.

in International Immunology

January 1998; p ublished online January 1998 .

Journal Article. Subjects: Immunology; Biological Sciences. 0 words.

We previously reported that intracellular oxidation-reduction (redox) regulates NK cell functions and that IL-2-activated NK cells undergo apoptosis upon contact with NK-sensitive target...

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Cellular MRI as a suitable, sensitive non-invasive modality for correlating in vivo migratory efficiencies of different dendritic cell populations with subsequent immunological outcomes

Sonali de Chickera, Christy Willert, Christiane Mallet, Ronan Foley, Paula Foster and Gregory A. Dekaban.

in International Immunology

January 2012; p ublished online December 2011 .

Journal Article. Subjects: Immunology; Biological Sciences. 7496 words.

The clinical application of dendritic cells (DC) as adjuvants in immunotherapies such as the cell-based cancer vaccine continues to gain interest. The overall efficacy of this emerging...

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Rapid Detection of Hepatitis B Virus in Blood Plasma by a Specific and Sensitive Loop-Mediated Isothermal Amplification Assay

Dougbeh-Chris Nyan, Laura E. Ulitzky, Nicoleta Cehan, Phillip Williamson, Valerie Winkelman, Maria Rios and Deborah R. Taylor.

in Clinical Infectious Diseases

July 2014; p ublished online April 2014 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 4558 words.

Background.  Hepatitis B virus (HBV) is an important blood-borne pathogen that causes hepatic inflammation and can lead to liver cirrhosis and...

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Targeting of the Purine Biosynthesis Host Cell Pathway Enhances the Activity of Tenofovir Against Sensitive and Drug-Resistant HIV-1

Alonso Heredia, Charles E. Davis, Marvin S. Reitz, Nhut M. Le, Mark A. Wainberg, James S. Foulke, Lai-Xi Wang and Robert R. Redfield.

in The Journal of Infectious Diseases

December 2013; p ublished online August 2013 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 5391 words.

Background.  Targeting host-cell pathways to increase the potency of nucleoside/nucleotide analog reverse transcriptase inhibitors (NRTIs) is an...

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Verapamil-Sensitive Transport of Quinacrine and Methylene Blue via the Plasmodium falciparum Chloroquine Resistance Transporter Reduces the Parasite's Susceptibility to these Tricyclic Drugs

Donelly A. van Schalkwyk, Megan N. Nash, Sarah H. Shafik, Robert L. Summers, Adele M. Lehane, Peter J. Smith and Rowena E. Martin.

in The Journal of Infectious Diseases

March 2016; p ublished online October 2015 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 7346 words.

Background.  It is becoming increasingly apparent that certain mutations in the Plasmodium falciparum chloroquine resistance transporter (PfCRT)...

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Polymerase Chain Reaction Is More Sensitive than Viral Culture and Antigen Testing for the Detection of Respiratory Viruses in Adults with Hematological Cancer and Pneumonia

Leontine J. R. van Elden, Marian G. J. van Kraaij, Monique Nijhuis, Karin A. W. Hendriksen, Ad W. Dekker, Maja Rozenberg-Arska and Anton M. van Loon.

in Clinical Infectious Diseases

January 2002; p ublished online January 2002 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 4345 words.

We retrospectively analyzed the value of polymerase chain reaction (PCR) for the detection of respiratory viral infections in 43 patients with hematological cancer whose bronchoalveolar...

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Sensitive Tenofovir Resistance Screening of HIV-1 From the Genital and Blood Compartments of Women With Breakthrough Infections in the CAPRISA 004 Tenofovir Gel Trial

Xierong Wei, Gillian Hunt, Salim S. Abdool Karim, Vivek Naranbhai, Sengeziwe Sibeko, Quarraisha Abdool Karim, Jin-fen Li, Angela D. M. Kashuba, Lise Werner, Jo-Ann S. Passmore, Lynn Morris, Walid Heneine and Jeffrey A. Johnson.

in The Journal of Infectious Diseases

June 2014; p ublished online January 2014 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 3310 words.

The Centre for the AIDS Programme of Research in South Africa 004 (CAPRISA 004) study demonstrated that vaginally applied tenofovir gel is a promising intervention for protecting women from...

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PCR as a rapid and sensitive tool in the diagnosis of human and canine leishmaniasis using Leishmania donovani s.l.-specific kinetoplastid primers

S. Cortes, N. Rolão, J. Ramada and L. Campino.

in Transactions of The Royal Society of Tropical Medicine and Hygiene

January 2004; p ublished online January 2004 .

Journal Article. Subjects: Clinical Medicine; Infectious Diseases; Immunology; Medical Microbiology and Virology; Public Health and Epidemiology. 2892 words.

Abstract

This study was performed in order to test the efficacy of a new polymerase chain reaction (PCR) assay for the diagnosis of both human and canine...

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Evaluation of Two Live, Cold-Passaged, Temperature-Sensitive Respiratory Syncytial Virus Vaccines in Chimpanzees and in Human Adults, Infants, and Children

Ruth A. Karron, Peter F. Wright, James E. Crowe, Mary Lou Clements Mann, Juliette Thompson, Mamodikoe Makhene, Roberta Casey and Brian R. Murphy.

in The Journal of Infectious Diseases

December 1997; p ublished online December 1997 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 0 words.

Two live-attenuated, cold-passaged (cp), temperature-sensitive (ts) candidate vaccines, designated cpts530/1009 and cpts248/955, were attenuated, genetically stable, and immunogenic in...

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Impact of Antibiotics on Expression of Virulence-Associated Exotoxin Genes in Methicillin-Sensitive and Methicillin-Resistant Staphylococcus aureus

in The Journal of Infectious Diseases

January 2007; p ublished online January 2007 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 5237 words.

Extracellular protein toxins contribute to the pathogenesis of a wide variety of Staphylococcus aureus infections. The present study investigated the effects that cell-wall active...

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Rapid Assembly of Sensitive Antigen-Capture Assays for Marburg Virus, Using In Vitro Selection of Llama Single-Domain Antibodies, at Biosafety Level

Laura J. Sherwood, Ricardo Carrion Osborn, Jean L. Patterson and Andrew Hayhurst.

in The Journal of Infectious Diseases

November 2007; p ublished online November 2007 .

Journal Article. Subjects: Infectious Diseases; Immunology; Public Health and Epidemiology; Microbiology. 3886 words.

There is a pressing need for rapid and reliable approaches to the delivery of sensitive yet rugged diagnostic assays specific for emerging viruses, to hasten containment of outbreaks when...

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