sensitive
Overview page. Subjects: Medicine and Health.
adj. possessing the ability to respond to a stimulus. The cells of the retina, for example, are sensitive to the stimulus of light and respond by sending nerve impulses to the...
In vivo sensitivity of the embryonic and adult neural stem cell compartments to low-dose radiation
in Journal of Radiation Research
August 2016; p ublished online August 2016 .
Journal Article. Subjects: Clinical Genetics; Molecular Biology and Genetics; Epidemiology; Radiology; Nuclear Chemistry, Photochemistry, and Radiation. 5997 words.
The embryonic brain is radiation-sensitive, with cognitive deficits being observed after exposure to low radiation doses. Exposure of neonates to radiation can cause intracranial...
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General ion recombination effect in a liquid ionization chamber in high-dose-rate pulsed photon and electron beams
in Journal of Radiation Research
May 2018; p ublished online January 2018 .
Journal Article. Subjects: Clinical Genetics; Molecular Biology and Genetics; Epidemiology; Radiology; Nuclear Chemistry, Photochemistry, and Radiation. 2237 words.
Abstract
Liquid ionization chambers (LICs) are highly sensitive to dose irradiation and have small perturbations because of their liquid-filled sensitive...
NBS1 and multiple regulations of DNA damage response
in Journal of Radiation Research
August 2016; p ublished online August 2016 .
Journal Article. Subjects: Clinical Genetics; Molecular Biology and Genetics; Epidemiology; Radiology; Nuclear Chemistry, Photochemistry, and Radiation. 4836 words.
DNA damage response is finely tuned, with several pathways including those for DNA repair, chromatin remodeling and cell cycle checkpoint, although most studies to date have focused on...
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Two Major Factors Involved in the Reverse Dose-rate Effect for Somatic Mutation Induction are the Cell Cycle Position and LET Value
in Journal of Radiation Research
September 2009; p ublished online June 2009 .
Journal Article. Subjects: Clinical Genetics; Molecular Biology and Genetics; Epidemiology; Radiology; Nuclear Chemistry, Photochemistry, and Radiation. 0 words.
To study mechanisms which could be involved in the reverse dose rate effect observed during mutation induction after exposure to high LET radiation, synchronized mouse L5178Y cells were...
Analysis of p53 Dependent Damage Response in Sperm-irradiated Mouse Embryos
in Journal of Radiation Research
January 2009; p ublished online January 2009 .
Journal Article. Subjects: Clinical Genetics; Molecular Biology and Genetics; Epidemiology; Radiology; Nuclear Chemistry, Photochemistry, and Radiation. 0 words.
Ionizing radiation activates a series of DNA damage response, cell cycle checkpoints to arrest cells at G1/S, S and G2/M, DNA repair, and apoptosis. The DNA damage response is thought to be...
Effects of water on fingernail electron paramagnetic resonance dosimetry
in Journal of Radiation Research
September 2016; p ublished online September 2016 .
Journal Article. Subjects: Clinical Genetics; Molecular Biology and Genetics; Epidemiology; Radiology; Nuclear Chemistry, Photochemistry, and Radiation. 5565 words.
Electron paramagnetic resonance (EPR) is a promising biodosimetric method, and fingernails are sensitive biomaterials to ionizing radiation. Therefore, kinetic energy released per unit mass...
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Identification of low-dose responsive metabolites in X-irradiated human B lymphoblastoid cells and fibroblasts
in Journal of Radiation Research
January 2015; p ublished online September 2014 .
Journal Article. Subjects: Clinical Genetics; Molecular Biology and Genetics; Epidemiology; Radiology; Nuclear Chemistry, Photochemistry, and Radiation. 5054 words.
Ionizing radiation (IR) induces cellular stress responses, such as signal transduction, gene expression, protein modification, and metabolite change that affect cellular behavior. We...
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Metabolomic screening using ESI-FT MS identifies potential radiation-responsive molecules in mouse urine
in Journal of Radiation Research
May 2017; p ublished online December 2016 .
Journal Article. Subjects: Clinical Genetics; Molecular Biology and Genetics; Epidemiology; Radiology; Nuclear Chemistry, Photochemistry, and Radiation. 3469 words.
Abstract
The demand for establishment of high-throughput biodosimetric methods is increasing. Our aim in this study was to identify low-molecular-weight...
Determining survival fractions of Saccharomyces cerevisiae in response to ionizing radiation in liquid culture
in Journal of Radiation Research
November 2018; p ublished online August 2018 .
Journal Article. Subjects: Clinical Genetics; Molecular Biology and Genetics; Epidemiology; Radiology; Nuclear Chemistry, Photochemistry, and Radiation. 1954 words.
Abstract
Saccharomyces cerevisiae survival fractions (SFs) in response to X-ray radiation were determined by two new methods: an OD600-based...
Upregulation of microRNA-98 increases radiosensitivity in esophageal squamous cell carcinoma
in Journal of Radiation Research
September 2016; p ublished online September 2016 .
Journal Article. Subjects: Clinical Genetics; Molecular Biology and Genetics; Epidemiology; Radiology; Nuclear Chemistry, Photochemistry, and Radiation. 4615 words.
Although radiation resistance is a common challenge in the clinical treatment of esophageal squamous cell carcinoma (ESCC), an effective treatment strategy has yet to be developed. Aberrant...
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Profiling of low molecular weight proteins in plasma from locally irradiated individuals
in Journal of Radiation Research
July 2014; p ublished online February 2014 .
Journal Article. Subjects: Clinical Genetics; Molecular Biology and Genetics; Epidemiology; Radiology; Nuclear Chemistry, Photochemistry, and Radiation. 4974 words.
In studies reported in the 1960s and since, blood plasma from radiation-exposed individuals has been shown to induce chromosome damage when transferred into lymphocyte cultures of...
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Mutations in the FHA-domain of ectopically expressed NBS1 lead to radiosensitization and to no increase in somatic mutation rates via a partial suppression of homologous recombination
in Journal of Radiation Research
July 2014; p ublished online March 2014 .
Journal Article. Subjects: Clinical Genetics; Molecular Biology and Genetics; Epidemiology; Radiology; Nuclear Chemistry, Photochemistry, and Radiation. 4570 words.
Ionizing radiation induces DNA double-strand breaks (DSBs). Mammalian cells repair DSBs through multiple pathways, and the repair pathway that is utilized may affect cellular radiation...
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Telomere length in Chernobyl accident recovery workers in the late period after the disaster
in Journal of Radiation Research
November 2014; p ublished online July 2014 .
Journal Article. Subjects: Clinical Genetics; Molecular Biology and Genetics; Epidemiology; Radiology; Nuclear Chemistry, Photochemistry, and Radiation. 7093 words.
The outcome of the Chernobyl nuclear power plant (CNPP) accident was that a huge number of people were exposed to ionizing radiation. Previous studies of CNPP clean-up workers from Latvia...
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Increased effectiveness of carbon ions in the production of reactive oxygen species in normal human fibroblasts
in Journal of Radiation Research
January 2015; p ublished online October 2014 .
Journal Article. Subjects: Clinical Genetics; Molecular Biology and Genetics; Epidemiology; Radiology; Nuclear Chemistry, Photochemistry, and Radiation. 5369 words.
The production of reactive oxygen species (ROS), especially superoxide anions (O2 ·–), is enhanced in many normal and tumor cell types in response to ionizing radiation. The...
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High susceptibility of mouse newborns to delayed appearance of DNA double-strand breaks in neural stem/progenitor cells exposed to ionizing radiation
in Journal of Radiation Research
November 2018; p ublished online August 2018 .
Journal Article. Subjects: Clinical Genetics; Molecular Biology and Genetics; Epidemiology; Radiology; Nuclear Chemistry, Photochemistry, and Radiation. 4857 words.
Abstract
Fetal brains are known to be extremely sensitive to ionizing radiation, which can induce structural and functional defects in the developing brain....
