Oxford Index Search Results

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sensitive x Clinical Medicine x Psychiatry x clear all

sensitive

Overview page. Subjects: Medicine and Health.

adj. possessing the ability to respond to a stimulus. The cells of the retina, for example, are sensitive to the stimulus of light and respond by sending nerve impulses to the...

See overview in Oxford Index

Lack of Antidepressant Effects of Low-Voltage-Sensitive T-Type Calcium Channel Blocker Ethosuximide in a Chronic Social Defeat Stress Model: Comparison with (R)-Ketamine

Zheng Tian, Chao Dong, Kai Zhang, Lijia Chang and Kenji Hashimoto.

in International Journal of Neuropsychopharmacology

P ublished online August 2018 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Neurology; Psychiatry; Neuroscience. 3298 words.

Abstract

Background

A recent study demonstrated that low-voltage-sensitive T-type calcium channel blocker...

Cross-Cultural Issues

William S. Breitbart.

in Psychosocial Palliative Care

April 2014; p ublished online August 2014 .

Chapter. Subjects: Palliative Medicine; Psychiatry. 6463 words.

Across cultures, the universal fear of cancer and other terminal illnesses are caused by the fear of death as well as images associated with debility and pain. Yet individual societies...

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Pathophysiology of Alzheimer’s disease

Shelley J. Allen.

in Alzheimer's Disease

March 2017; p ublished online April 2017 .

Chapter. Subjects: Neurology; Psychiatry. 4714 words.

We now know that the onset of the pathological processes leading to Alzheimer’s disease (AD) may be 15–20 years before symptoms appear. This focuses attention on synaptic changes and the...

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Caring for people with dementia towards and at the end of life

Louise Robinson.

in Alzheimer's Disease

March 2017; p ublished online April 2017 .

Chapter. Subjects: Neurology; Psychiatry. 3033 words.

Research evidence confirms that people dying with dementia receive suboptimal care compared to those with terminal cancer. Good quality end-of-life care in dementia can be achieved. It...

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Neurobiology of Lewy Body Dementias

James E. Galvin and Jose Tomas Bras.

in Charney & Nestler's Neurobiology of Mental Illness

November 2017; p ublished online December 2017 .

Chapter. Subjects: Neurology; Psychiatry. 11961 words.

Lewy body dementia (LBD) is the second most common form of neurocognitive disorder after Alzheimer’s disease and covers two related diagnoses: Dementia with Lewy Bodies and Parkinson’s...

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Complementary, Alternative, and Integrative Medicine in the Treatment and Management of Dementia

Bruce J. Diamond, Susan K. Johnson, Katelyn Van Clef, Stephanie Magou and Briana Stanfield.

in Complementary and Integrative Therapies for Mental Health and Aging

December 2015; p ublished online March 2016 .

Chapter. Subjects: Psychiatry; Geriatric Medicine. 13747 words.

Dementia is a devastating disorder with a profound impact on individuals, families, and societies. Evidence-based complementary, alternative, and integrative interventions may provide...

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Prion diseases

Simon Mead, Peter Rudge and John Collinge.

in Oxford Textbook of Cognitive Neurology and Dementia

June 2016; p ublished online July 2016 .

Chapter. Subjects: Neurology; Psychiatry. 7468 words.

Prion diseases are fatal and transmissible neurodegenerative disorders of humans and animals. They are caused by the seeded polymerization of host prion protein into a misfolded form. The...

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Think family: systemic therapy in later life

Susan M. Benbow and Gillian Goodwillie.

in Casebook of clinical geropsychology

September 2010; p ublished online February 2013 .

Chapter. Subjects: Psychiatry; Geriatric Medicine. 8332 words.

This chapter will describe three ideas that are important to systemic practice when working transgenerationally with a special focus on implications for work with older families. These are:...

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The TRACK-TBI Approach: Redefining Severity and Outcome Assessments

John K. Yue, Ethan A. Winkler, Hansen Deng, Amy J. Markowitz, Kevin K. W. Wang and Geoffrey T. Manley.

in Neurotrauma

November 2018; p ublished online November 2018 .

Chapter. Subjects: Neurology; Psychiatry; Clinical Neuroscience. 7876 words.

Advances in traumatic brain injury (TBI) research have been limited by imprecise classification and diagnostic approaches and insensitive outcome measures. The National Institute of...

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Neuroimaging and Its Application in the Diagnosis and Early Prognostication of TBI

Lijun Bai, Shan Wang and Chuanzhu Sun.

in Neurotrauma

November 2018; p ublished online November 2018 .

Chapter. Subjects: Neurology; Psychiatry; Clinical Neuroscience. 2924 words.

Traumatic brain injury (TBI) is a substantial public health problem. Differences in the progress of recovery make it a heterogeneous injury and limit effective diagnostic tools that depend...

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Religion and Spirituality in Gerontology

Harold G. Koenig.

in Spirituality and Religion Within the Culture of Medicine

May 2017; p ublished online May 2017 .

Chapter. Subjects: Psychiatry; Palliative Medicine; Clinical Medicine. 9169 words.

This chapter provides a state-of-the-science review of research on religion, spirituality, and health in later life; examines avenues for future research; explores how religion or...

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Pharmacokinetics and Pharmacodynamics in Late Life

Kristin L. Bigos, Robert R. Bies and Bruce G. Pollock.

in Late-Life Mood Disorders

February 2013; p ublished online June 2013 .

Chapter. Subjects: Old Age Psychiatry; Neurology. 12248 words.

Older patients are the major recipients of drugs, however most research during drug development is conducted in healthy younger adults. Adverse drug events are common in older adults, but...

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Face perception enhances insula and motor network reactivity in Tourette syndrome

Charlotte L Rae, Liliana Polyanska, Cassandra D Gould van Praag, Jim Parkinson, Samira Bouyagoub, Yoko Nagai, Anil K Seth, Neil A Harrison, Sarah N Garfinkel and Hugo D Critchley.

in Brain

November 2018; p ublished online October 2018 .

Journal Article. Subjects: Neuroscience; Neurology; Psychiatry. 8792 words.

Abstract

Tourette syndrome is a neurodevelopmental disorder, characterized by motor and phonic tics. Tics are typically experienced as avolitional, compulsive,...

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Glial and axonal changes in systemic lupus erythematosus measured with diffusion of intracellular metabolites

Ece Ercan, Cesar Magro-Checa, Romain Valabregue, Francesca Branzoli, Emily T. Wood, Gerda M. Steup-Beekman, Andrew G. Webb, Tom W. J. Huizinga, Mark A. van Buchem and Itamar Ronen.

in Brain

May 2016; p ublished online March 2016 .

Journal Article. Subjects: Neuroscience; Neurology; Psychiatry. 6382 words.

Systemic lupus erythematosus is an inflammatory autoimmune disease with multi-organ involvement. Central nervous system involvement in systemic lupus erythematosus is common and results in...

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S-Ketamine Rapidly Reverses Synaptic and Vascular Deficits of Hippocampus in Genetic Animal Model of Depression

Maryam Ardalan, Gregers Wegener, Ali H. Rafati and Jens R. Nyengaard.

in International Journal of Neuropsychopharmacology

P ublished online December 2016 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Neurology; Psychiatry; Neuroscience. 7012 words.

Abstract

Background:

The neurovascular plasticity of hippocampus is an important theory underlying major...

Biomarkers of pain: physiological indices of pain reactivity in infants and children

Susanne Brummelte, Tim F. Oberlander and Kenneth D. Craig.

in Oxford Textbook of Paediatric Pain

November 2013; p ublished online November 2013 .

Chapter. Subjects: Anaesthetics; Paediatrics; Child and Adolescent Psychiatry; Pain Medicine. 9079 words.

Biomarkers are common in all areas of clinical work, health research, and are critical indicators of diseases and physiological states. Preferably, a biomarker should be non-invasively...

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Fenfluramine Reduces [11C]Cimbi-36 Binding to the 5-HT2A Receptor in the Nonhuman Primate Brain

Kai-Chun Yang, Vladimir Stepanov, Stefan Martinsson, Anders Ettrup, Akihiro Takano, Gitte M Knudsen, Christer Halldin, Lars Farde and Sjoerd J Finnema.

in International Journal of Neuropsychopharmacology

P ublished online June 2017 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Neurology; Psychiatry; Neuroscience. 5922 words.

Abstract

Background

[11C]Cimbi-36 is a serotonin 2A receptor agonist positron emission tomography radioligand that...

Induction of Cannabinoid- and N-Methyl-d-Aspartate Receptor-Mediated Long-Term Depression in the Nucleus Accumbens and Dorsolateral Striatum Is Region and Age Dependent

Xiaoqun Zhang, Ze-Jun Feng and Karima Chergui.

in International Journal of Neuropsychopharmacology

P ublished online January 2015 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Neurology; Psychiatry; Neuroscience. 5585 words.

Background:

The adolescent brain is sensitive to experience-dependent plasticity and might be more vulnerable than the adult brain to the effects of some...

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Manganese-Enhanced Magnetic Resonance Imaging Reveals Differential Long-Term Neuroadaptation After Methamphetamine and the Substituted Cathinone 4-Methylmethcathinone (Mephedrone)

Bjørnar den Hollander, Mateusz Dudek, Ilkka Ojanperä, Esko Kankuri, Petri Hyytiä and Esa R Korpi.

in International Journal of Neuropsychopharmacology

April 2015; p ublished online February 2015 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Neurology; Psychiatry; Neuroscience. 7305 words.

Background:

In recent years there has been a large increase in the use of substituted cathinones such as mephedrone (4-methylmethcathinone, 4-MMC), a...

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5-HT1A Agonist Properties Contribute to a Robust Response to Vilazodone in the Novelty Suppressed Feeding Paradigm

Alvaro L. Garcia-Garcia, Míriam Navarro-Sobrino, Gila Pilosof, Pradeep Banerjee, Alex Dranovsky and E. David Leonardo.

in International Journal of Neuropsychopharmacology

P ublished online June 2016 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Neurology; Psychiatry; Neuroscience. 4190 words.

Background:

Differences in 5-HT1A receptor function have been implicated in vulnerability to depression and in response to treatment. Adding 5-HT1A partial...

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