Oxford Index Search Results

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sensitive x Clinical Medicine x Radiology x clear all

sensitive

Overview page. Subjects: Medicine and Health.

adj. possessing the ability to respond to a stimulus. The cells of the retina, for example, are sensitive to the stimulus of light and respond by sending nerve impulses to the...

See overview in Oxford Index

A Phase II clinical trial of pegylated liposomal doxorubicin and carboplatin in Japanese patients with platinum-sensitive recurrent ovarian, fallopian tube or primary peritoneal cancer

Toru Nakanishi, Daisuke Aoki, Yoh Watanabe, Yuichi Ando, Naoki Tomotsugu, Yuji Sato and Toshiaki Saito.

in Japanese Journal of Clinical Oncology

May 2015; p ublished online February 2015 .

Journal Article. Subjects: Clinical Medicine; Medical Oncology; Radiation Oncology; Surgical Oncology. 3241 words.

Objective

This single-arm Phase II trial was designed to assess the safety and efficacy of pegylated liposomal doxorubicin and carboplatin combination...

Cervical Transforaminal/Nerve Root Injections: Computed Tomography

Tilman Wolter.

in Multimodality Imaging Guidance in Interventional Pain Management

October 2016; p ublished online October 2016 .

Chapter. Subjects: Pain Medicine; Radiology. 4910 words.

Computed tomography (CT)–guided selective cervical nerve root blocks, particularly in the dorsal/posterior access, are sensitive, specific, efficacious, and safe. If performed with a...

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Hip Joint Injections: Ultrasound

Hariharan Shankar and Marina Vardanyan.

in Multimodality Imaging Guidance in Interventional Pain Management

October 2016; p ublished online October 2016 .

Chapter. Subjects: Pain Medicine; Radiology. 2530 words.

Hip pain is a common presentation in medical practice, and causes include osteoarthritis, rheumatoid arthritis, congenital hip abnormalities, and trauma. Chronic hip pain significantly...

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Echocardiography and detection of coronary artery disease

Rosa Sicari.

in The ESC Textbook of Cardiovascular Imaging

March 2015; p ublished online May 2015 .

Chapter. Subjects: Cardiovascular Medicine; Radiology. 5769 words.

Coronary artery disease provokes an imbalance between myocardial oxygen supply and demand inducing myocardial ischaemia and infarction. Myocardial ischaemia causes left ventricular regional...

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Facet Joint Interventions: Fluoroscopy

David Jamison, Indy Wilkinson and Steven P. Cohen.

in Multimodality Imaging Guidance in Interventional Pain Management

October 2016; p ublished online October 2016 .

Chapter. Subjects: Pain Medicine; Radiology. 13593 words.

This chapter reviews the diagnosis and treatment of facet joint pain. Fluoroscopic guidance is commonly used to optimize treatment outcomes. The only reliable way to identify a painful...

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Myocarditis

Heiko Mahrholdt, Ali Yilmaz and Udo Sechtem.

in The ESC Textbook of Cardiovascular Imaging

March 2015; p ublished online May 2015 .

Chapter. Subjects: Cardiovascular Medicine; Radiology. 7547 words.

The symptoms and signs of myocarditis are non-specific. Thus, myocarditis is a differential diagnosis in many patients with heart complaints. As clinical tools, such as history taking,...

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Solitary plasmacytoma

Isabella Maund and Michael Williams.

in Oxford Case Histories in Oncology

February 2014; p ublished online April 2014 .

Chapter. Subjects: Radiation Oncology; Palliative Medicine. 1563 words.

Solitary plasmacytoma of bone is a rare but, potentially curable tumour. The histological finding of a plasma cell neoplasm should initiate investigations to determine whether there are...

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Tuberculosis

Sonia L. Betancourt.

in Chest Imaging

July 2019; p ublished online August 2019 .

Chapter. Subjects: Radiology; Clinical Radiology; Respiratory Medicine and Pulmonology. 1579 words.

Tuberculosis (TB) is an airborne infection caused by Mycobacterium tuberculosis, an obligate aerobe, nonmotile, non-spore-forming bacillus. TB is a major cause of morbidity and mortality...

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Traditional and Complementary Medicine in Pediatric Oncology and Low-Middle Income Countries: Recommendations from the International Society of Pediatric Oncology (SIOP), T&CM Collaborative

Elena J. Ladas, Stacey Marjerrison, Brijesh Arora, Peter B. Hesseling, Roberta Ortiz, Federico Antillon, Shalini Jatia and Glenn M. Afungchwi.

in Journal of the National Cancer Institute Monographs

November 2017; p ublished online November 2017 .

Journal Article. Subjects: Medical Oncology; Radiation Oncology; Surgical Oncology. 2342 words.

Abstract

Significant strides have been made in the treatment of childhood cancer. Improvements in survival have led to increased attention toward supportive...

Small Cell Lung Cancer Screen of Oncology Drugs, Investigational Agents, and Gene and microRNA Expression

Eric Polley, Mark Kunkel, David Evans, Thomas Silvers, Rene Delosh, Julie Laudeman, Chad Ogle, Russell Reinhart, Michael Selby, John Connelly, Erik Harris, Nicole Fer, Dmitriy Sonkin, Gurmeet Kaur, Anne Monks, Shakun Malik, Joel Morris and Beverly A. Teicher.

in JNCI: Journal of the National Cancer Institute

P ublished online May 2016 .

Journal Article. Subjects: Medical Oncology; Radiation Oncology; Surgical Oncology. 6140 words.

Background: Small cell lung carcinoma (SCLC) is an aggressive, recalcitrant cancer, often metastatic at diagnosis and unresponsive to chemotherapy upon recurrence, thus it is...

Nicotinamide Phosphoribosyltransferase (NAMPT) as a Therapeutic Target in BRAF-Mutated Metastatic Melanoma

Valentina Audrito, Antonella Managò, Sofia La Vecchia, Federica Zamporlini, Nicoletta Vitale, Gianna Baroni, Simona Cignetto, Sara Serra, Cinzia Bologna, Aureliano Stingi, Francesca Arruga, Tiziana Vaisitti, Daniela Massi, Mario Mandalà, Nadia Raffaelli and Silvia Deaglio.

in JNCI: Journal of the National Cancer Institute

P ublished online September 2017 .

Journal Article. Subjects: Medical Oncology; Radiation Oncology; Surgical Oncology. 6872 words.

Abstract

Background

One of the effects of oncogenic signaling is metabolic reprogramming of tumor cells to support...

Weighing Risk of Cardiovascular Mortality Against Potential Benefit of Hormonal Therapy in Intermediate-Risk Prostate Cancer

Nataniel H. Lester-Coll, Skyler Johnson, William J. Magnuson, Samuel Z. Goldhaber, David J. Sher, Anthony V. D’Amico and James B. Yu.

in JNCI: Journal of the National Cancer Institute

June 2017; p ublished online December 2016 .

Journal Article. Subjects: Medical Oncology; Radiation Oncology; Surgical Oncology. 5599 words.

Abstract

Background: The purpose of this study is to determine the optimal strategy for men with newly diagnosed intermediate-risk prostate cancer...

Loss of DNA Damage Response in Neuroblastoma and Utility of a PARP Inhibitor

Masatoshi Takagi, Misa Yoshida, Yoshino Nemoto, Hiroyuki Tamaichi, Rika Tsuchida, Masafumi Seki, Kumiko Uryu, Rina Nishii, Satoshi Miyamoto, Masahiro Saito, Ryoji Hanada, Hideo Kaneko, Satoru Miyano, Keisuke Kataoka, Kenichi Yoshida, Miki Ohira, Yasuhide Hayashi, Akira Nakagawara, Seishi Ogawa, Shuki Mizutani and Junko Takita.

in JNCI: Journal of the National Cancer Institute

P ublished online August 2017 .

Journal Article. Subjects: Medical Oncology; Radiation Oncology; Surgical Oncology. 5956 words.

Abstract

Background: Neuroblastoma (NB) is the most common solid tumor found in children, and deletions within the 11q region are observed in 11%...

Next-Generation CDK2/9 Inhibitors and Anaphase Catastrophe in Lung Cancer

Masanori Kawakami, Lisa Maria Mustachio, Jaime Rodriguez-Canales, Barbara Mino, Jason Roszik, Pan Tong, Jing Wang, J. Jack Lee, Ja Hye Myung, John V. Heymach, Faye M. Johnson, Seungpyo Hong, Lin Zheng, Shanhu Hu, Pamela Andrea Villalobos, Carmen Behrens, Ignacio Wistuba, Sarah Freemantle, Xi Liu and Ethan Dmitrovsky.

in JNCI: Journal of the National Cancer Institute

June 2017; p ublished online February 2017 .

Journal Article. Subjects: Medical Oncology; Radiation Oncology; Surgical Oncology. 5855 words.

Abstract

Background: The first generation CDK2/7/9 inhibitor seliciclib (CYC202) causes multipolar anaphase and apoptosis in lung cancer cells...

In vivo sensitivity of the embryonic and adult neural stem cell compartments to low-dose radiation

Lara Barazzuol and Penny A. Jeggo.

in Journal of Radiation Research

August 2016; p ublished online August 2016 .

Journal Article. Subjects: Clinical Genetics; Molecular Biology and Genetics; Epidemiology; Radiology; Nuclear Chemistry, Photochemistry, and Radiation. 5997 words.

The embryonic brain is radiation-sensitive, with cognitive deficits being observed after exposure to low radiation doses. Exposure of neonates to radiation can cause intracranial...

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General ion recombination effect in a liquid ionization chamber in high-dose-rate pulsed photon and electron beams

Hideyuki Takei, Tomonori Isobe, Nozomi Kitamura, Yutaro Mori, Tetsuya Tomita, Daisuke Kobayashi, Satoshi Kamizawa, Tomoharu Sato, Hideyuki Sakurai and Takeji Sakae.

in Journal of Radiation Research

May 2018; p ublished online January 2018 .

Journal Article. Subjects: Clinical Genetics; Molecular Biology and Genetics; Epidemiology; Radiology; Nuclear Chemistry, Photochemistry, and Radiation. 2237 words.

Abstract

Liquid ionization chambers (LICs) are highly sensitive to dose irradiation and have small perturbations because of their liquid-filled sensitive...

Pharmacotherapy for recurrent ovarian cancer: current status and future perspectives

Koji Matsumoto, Takashi Onda and Nobuo Yaegashi.

in Japanese Journal of Clinical Oncology

May 2015; p ublished online March 2015 .

Journal Article. Subjects: Clinical Medicine; Medical Oncology; Radiation Oncology; Surgical Oncology. 1974 words.

Several ‘lines of therapy’ that utilize cytotoxic agents and are driven by platinum-free intervals are the current standard of care for patients with recurrent ovarian cancer. For patients...

NBS1 and multiple regulations of DNA damage response

Kenshi Komatsu.

in Journal of Radiation Research

August 2016; p ublished online August 2016 .

Journal Article. Subjects: Clinical Genetics; Molecular Biology and Genetics; Epidemiology; Radiology; Nuclear Chemistry, Photochemistry, and Radiation. 4836 words.

DNA damage response is finely tuned, with several pathways including those for DNA repair, chromatin remodeling and cell cycle checkpoint, although most studies to date have focused on...

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Two Major Factors Involved in the Reverse Dose-rate Effect for Somatic Mutation Induction are the Cell Cycle Position and LET Value

Hiroshi Tauchi, Hiroyuki Waku, Eigo Matsumoto, Sayaka Yara, Shino Okumura, Yoshiyuki Iwata, Kenshi Komatsu, Yoshiya Furusawa, Kiyomi Eguchi-Kasai and Akira Tachibana.

in Journal of Radiation Research

September 2009; p ublished online June 2009 .

Journal Article. Subjects: Clinical Genetics; Molecular Biology and Genetics; Epidemiology; Radiology; Nuclear Chemistry, Photochemistry, and Radiation. 0 words.

To study mechanisms which could be involved in the reverse dose rate effect observed during mutation induction after exposure to high LET radiation, synchronized mouse L5178Y cells were...

Brain Metastases in Breast Cancer

Naoki Niikura, Shigehira Saji, Yutaka Tokuda and Hiroji Iwata.

in Japanese Journal of Clinical Oncology

December 2014; p ublished online October 2014 .

Journal Article. Subjects: Clinical Medicine; Medical Oncology; Radiation Oncology; Surgical Oncology. 5338 words.

Brain metastases are less common than bone or visceral metastases in patients with breast cancer. The overall prognosis of breast cancer patients with brain metastases remains poor, and...