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sensitive

Overview page. Subjects: Medicine and Health.

adj. possessing the ability to respond to a stimulus. The cells of the retina, for example, are sensitive to the stimulus of light and respond by sending nerve impulses to the...

See overview in Oxford Index

Mutations of the Twik-Related Acid-Sensitive K+ Channel 2 Promoter in Human Primary Aldosteronism

Livia Lenzini, Selene Prisco, Michele Gallina, Maniselvan Kuppusamy and Gian Paolo Rossi.

in Endocrinology

P ublished online December 2017 .

Journal Article. Subjects: Medicine and Health; Clinical Medicine; Endocrinology and Diabetes; Medical Oncology; Reproductive Medicine. 4488 words.

Abstract

Because blunted expression of the twik-related acid-sensitive K+ channel 2 (TASK-2) is a common feature of aldosterone-producing adenoma (APA) causing...

Redox-Sensitive Transcription Factor NRF2 Enhances Trophoblast Differentiation via Induction of miR-1246 and Aromatase

Sribalasubashini Muralimanoharan, Youn-Tae Kwak and Carole R Mendelson.

in Endocrinology

P ublished online March 2018 .

Journal Article. Subjects: Medicine and Health; Clinical Medicine; Endocrinology and Diabetes; Medical Oncology; Reproductive Medicine. 6789 words.

Abstract

Dysregulation of human trophoblast invasion and differentiation with placental hypoxia can result in preeclampsia, a hypertensive disorder of...

Morphological Analysis of the Axonal Projections of EGFP-Labeled Esr1-Expressing Neurons in Transgenic Female Medaka

Buntaro Zempo, Tomomi Karigo, Shinji Kanda, Yasuhisa Akazome and Yoshitaka Oka.

in Endocrinology

P ublished online December 2017 .

Journal Article. Subjects: Medicine and Health; Clinical Medicine; Endocrinology and Diabetes; Medical Oncology; Reproductive Medicine. 9347 words.

Abstract

Some hypothalamic neurons expressing estrogen receptor α (Esr1) are thought to transmit a gonadal estrogen feedback signal to gonadotropin-releasing...

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Diagnostic Utility of Molecular and Imaging Biomarkers in Cytological Indeterminate Thyroid Nodules

Elizabeth J de Koster, Lioe-Fee de Geus-Oei, Olaf M Dekkers, Ilse van Engen-van Grunsven, Jaap Hamming, Eleonora P M Corssmit, Hans Morreau, Abbey Schepers, Jan Smit, Wim J G Oyen and Dennis Vriens.

in Endocrine Reviews

P ublished online January 2018 .

Journal Article. Subjects: Medicine and Health; Clinical Medicine; Endocrinology and Diabetes; Medical Oncology; Reproductive Medicine. 31503 words.

Abstract

Indeterminate thyroid cytology (Bethesda III and IV) corresponds to follicular-patterned benign and malignant lesions, which are particularly...

Prenatal Exposure to Unconventional Oil and Gas Operation Chemical Mixtures Altered Mammary Gland Development in Adult Female Mice

Sarah A Sapouckey, Christopher D Kassotis, Susan C Nagel and Laura N Vandenberg.

in Endocrinology

P ublished online February 2018 .

Journal Article. Subjects: Medicine and Health; Clinical Medicine; Endocrinology and Diabetes; Medical Oncology; Reproductive Medicine. 7541 words.

Abstract

Unconventional oil and gas (UOG) operations, which combine hydraulic fracturing (fracking) and directional drilling, involve the use of hundreds of...

Glibenclamide Prevents Hypoglycemia-Induced Fatal Cardiac Arrhythmias in Rats

Candace M Reno, Justin Bayles, Allie Skinner and Simon J Fisher.

in Endocrinology

P ublished online May 2018 .

Journal Article. Subjects: Medicine and Health; Clinical Medicine; Endocrinology and Diabetes; Medical Oncology; Reproductive Medicine. 4128 words.

Abstract

Sulfonylureas increase the incidence of severe hypoglycemia in people with type 2 diabetes and might increase the risk of sudden cardiac death....

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Comparing Postnatal Development of Gonadal Hormones and Associated Social Behaviors in Rats, Mice, and Humans

Margaret R Bell.

in Endocrinology

P ublished online May 2018 .

Journal Article. Subjects: Medicine and Health; Clinical Medicine; Endocrinology and Diabetes; Medical Oncology; Reproductive Medicine. 13240 words.

Abstract

Postnatal development includes dramatic changes in gonadal hormones and the many social behaviors they help regulate, both in rodents and humans....

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A Transgenic Mouse Model for Detection of Tissue-Specific Thyroid Hormone Action

Petra Mohácsik, Ferenc Erdélyi, Mária Baranyi, Bálint Botz, Gábor Szabó, Mónika Tóth, Irén Haltrich, Zsuzsanna Helyes, Beáta Sperlágh, Zsuzsa Tóth, Richárd Sinkó, Ronald M Lechan, Antonio C Bianco, Csaba Fekete and Balázs Gereben.

in Endocrinology

P ublished online December 2017 .

Journal Article. Subjects: Medicine and Health; Clinical Medicine; Endocrinology and Diabetes; Medical Oncology; Reproductive Medicine. 9254 words.

Abstract

Thyroid hormone (TH) is present in the systemic circulation and thus should affect all cells similarly in the body. However, tissues have a complex...

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Effects of Exposure to the Endocrine-Disrupting Chemical Bisphenol A During Critical Windows of Murine Pituitary Development

Kirsten S Eckstrum, Whitney Edwards, Annesha Banerjee, Wei Wang, Jodi A Flaws, John A Katzenellenbogen, Sung Hoon Kim and Lori T Raetzman.

in Endocrinology

P ublished online October 2017 .

Journal Article. Subjects: Medicine and Health; Clinical Medicine; Endocrinology and Diabetes; Medical Oncology; Reproductive Medicine. 9149 words.

Abstract

Critical windows of development are often more sensitive to endocrine disruption. The murine pituitary gland has two critical windows of development:...

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GLP-1 Receptor Expression Within the Human Heart

Laurie L Baggio, Bernardo Yusta, Erin E Mulvihill, Xiemin Cao, Catherine J Streutker, Jagdish Butany, Thomas P Cappola, Kenneth B Margulies and Daniel J Drucker.

in Endocrinology

P ublished online February 2018 .

Journal Article. Subjects: Medicine and Health; Clinical Medicine; Endocrinology and Diabetes; Medical Oncology; Reproductive Medicine. 6826 words.

Abstract

Glucagonlike peptide-1 receptor (GLP-1R) agonists, which are used to treat type 2 diabetes and obesity, reduce the rates of myocardial infarction and...

MiR-7 Mediates the Zearalenone Signaling Pathway Regulating FSH Synthesis and Secretion by Targeting FOS in Female Pigs

Jing He, Jinglin Zhang, Yue Wang, Weiquan Liu, Kemian Gou, Zongping Liu and Sheng Cui.

in Endocrinology

P ublished online May 2018 .

Journal Article. Subjects: Medicine and Health; Clinical Medicine; Endocrinology and Diabetes; Medical Oncology; Reproductive Medicine. 7635 words.

Abstract

Zearalenone (ZEA) acts as an environmental endocrine disruptor (EED) to cause health detriments. miRNAs were reported to influence the synthesis and...

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Urinary Cadmium Excretion Is Associated With Increased Synthesis of Cortico- and Sex Steroids in a Population Study

Murielle Bochud, Judith Jenny-Burri, Menno Pruijm, Belen Ponte, Idris Guessous, Georg Ehret, Dusan Petrovic, Vincent Dudler, Max Haldimann, Geneviève Escher, Bernhard Dick, Markus Mohaupt, Fred Paccaud, Michel Burnier, Antoinette Péchère-Bertschi, Pierre-Yves Martin, Bruno Vogt and Daniel Ackermann.

in The Journal of Clinical Endocrinology & Metabolism

P ublished online October 2017 .

Journal Article. Subjects: Medicine and Health; Clinical Medicine; Endocrinology and Diabetes; Medical Oncology; Reproductive Medicine. 7224 words.

Abstract

Context

Urinary cadmium (Cd) excretion is associated with cancer and cardiovascular morbidity. A potential...

Impact of C-Peptide Status on the Response of Glucagon and Endogenous Glucose Production to Induced Hypoglycemia in T1DM

Sabine Zenz, Julia K Mader, Werner Regittnig, Martina Brunner, Stefan Korsatko, Beate Boulgaropoulos, Christoph Magnes, Reingard Raml, Sophie H Narath, Philipp Eller, Thomas Augustin and Thomas R Pieber.

in The Journal of Clinical Endocrinology & Metabolism

P ublished online February 2018 .

Journal Article. Subjects: Medicine and Health; Clinical Medicine; Endocrinology and Diabetes; Medical Oncology; Reproductive Medicine. 6363 words.

Abstract

Context

Complete loss of β-cell function in patients with type 1 diabetes mellitus (T1DM) may lead to an...