Oxford Index Search Results

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sensitive x Clinical Medicine x Neuropathology x clear all

sensitive

Overview page. Subjects: Medicine and Health.

adj. possessing the ability to respond to a stimulus. The cells of the retina, for example, are sensitive to the stimulus of light and respond by sending nerve impulses to the...

See overview in Oxford Index

Cortisol fluctuations relate to interictal epileptiform discharges in stress sensitive epilepsy

Jolien S. van Campen, E. Lorraine Hompe, Floor E. Jansen, Demetrios N. Velis, Willem M. Otte, Fia van de Berg, Kees P. J. Braun, Gerhard H. Visser, Josemir W. Sander, Marian Joels and Maeike Zijlmans.

in Brain

June 2016; p ublished online March 2016 .

Journal Article. Subjects: Neuropathology; Disorders of the Nervous System; Sleep Medicine. 4093 words.

People with epilepsy often report seizures precipitated by stress. This is believed to be due to effects of stress hormones, such as cortisol, on neuronal excitability. Cortisol, regardless...

Dural and pial pain-sensitive structures in humans: new inputs from awake craniotomies

Denys Fontaine, Fabien Almairac, Serena Santucci, Charlotte Fernandez, Radhouane Dallel, Johan Pallud and Michel Lanteri-Minet.

in Brain

April 2018; p ublished online January 2018 .

Journal Article. Subjects: Neuropathology; Disorders of the Nervous System; Pain Medicine. 3753 words.

Abstract

Our knowledge on intracranial pain-sensitive structures in humans comes essentially from observations during neurosurgical procedures performed in...

A widespread visually-sensitive functional network relates to symptoms in essential tremor

Derek B Archer, Stephen A Coombes, Winston T Chu, Jae Woo Chung, Roxana G Burciu, Michael S Okun, Aparna Wagle Shukla and David E Vaillancourt.

in Brain

February 2018; p ublished online December 2017 .

Journal Article. Subjects: Neuropathology; Sensory and Motor Systems; Disorders of the Nervous System. 9306 words.

Abstract

Essential tremor is a neurological syndrome of heterogeneous pathology and aetiology that is characterized by tremor primarily in the upper...

Capsaicin-sensitive C- and A-fibre nociceptors control long-term potentiation-like pain amplification in humans

Florian Henrich, Walter Magerl, Thomas Klein, Wolfgang Greffrath and Rolf-Detlef Treede.

in Brain

September 2015; p ublished online May 2015 .

Journal Article. Subjects: Neuropathology; Disorders of the Nervous System; Pain Medicine. 10403 words.

Long-term potentiation in the spinal dorsal horn requires peptidergic C-fibre activation in animals. Perceptual correlates of long-term potentiation following high-frequency electrical...

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Optical coherence tomography in autosomal recessive spastic ataxia of Charlevoix-Saguenay

Michael H Parkinson, Ana P Bartmann, Lisa M S Clayton, Suran Nethisinghe, Rolph Pfundt, J Paul Chapple, Mary M Reilly, Hadi Manji, Nicholas J Wood, Fion Bremner and Paola Giunti.

in Brain

April 2018; p ublished online March 2018 .

Journal Article. Subjects: Neuropathology; Disorders of the Nervous System. 6221 words.

Abstract

Autosomal recessive spastic ataxia of Charlevoix-Saguenay is a rare neurodegenerative disorder caused by mutations in the SACS gene. Thickened retinal...

Cortical superficial siderosis: detection and clinical significance in cerebral amyloid angiopathy and related conditions

Andreas Charidimou, Jennifer Linn, Meike W. Vernooij, Christian Opherk, Saloua Akoudad, Jean-Claude Baron, Steven M. Greenberg, Hans Rolf Jäger and David J. Werring.

in Brain

August 2015; p ublished online June 2015 .

Journal Article. Subjects: Disorders of the Nervous System; Neuropathology. 8437 words.

Cortical superficial siderosis describes a distinct pattern of blood-breakdown product deposition limited to cortical sulci over the convexities of the cerebral hemispheres, sparing the...

Increased TRPC5 glutathionylation contributes to striatal neuron loss in Huntington’s disease

Chansik Hong, Hyemyung Seo, Misun Kwak, Jeha Jeon, Jihoon Jang, Eui Man Jeong, Jongyun Myeong, Yu Jin Hwang, Kotdaji Ha, Min Jueng Kang, Kyu Pil Lee, Eugene C. Yi, In-Gyu Kim, Ju-Hong Jeon, Hoon Ryu and Insuk So.

in Brain

October 2015; p ublished online July 2015 .

Journal Article. Subjects: Disorders of the Nervous System; Neuropathology. 8814 words.

Aberrant glutathione or Ca2+ homeostasis due to oxidative stress is associated with the pathogenesis of neurodegenerative disorders. The Ca2+-permeable transient receptor potential cation...

Military blast exposure, ageing and white matter integrity

Benjamin B. Trotter, Meghan E. Robinson, William P. Milberg, Regina E. McGlinchey and David H. Salat.

in Brain

August 2015; p ublished online June 2015 .

Journal Article. Subjects: Disorders of the Nervous System; Neuropathology. 9324 words.

Mild traumatic brain injury, or concussion, is associated with a range of neural changes including altered white matter structure. There is emerging evidence that blast exposure—one of the...

Network localization of neurological symptoms from focal brain lesions

Aaron D. Boes, Sashank Prasad, Hesheng Liu, Qi Liu, Alvaro Pascual-Leone, Verne S. Caviness and Michael D. Fox.

in Brain

October 2015; p ublished online August 2015 .

Journal Article. Subjects: Disorders of the Nervous System; Neuropathology. 7488 words.

A traditional and widely used approach for linking neurological symptoms to specific brain regions involves identifying overlap in lesion location across patients with similar symptoms,...

Your perspective and my benefit: multiple lesion models of self-other integration strategies during social bargaining

Margherita Melloni, Pablo Billeke, Sandra Baez, Eugenia Hesse, Laura de la Fuente, Gonzalo Forno, Agustina Birba, Indira García-Cordero, Cecilia Serrano, Angelo Plastino, Andrea Slachevsky, David Huepe, Mariano Sigman, Facundo Manes, Adolfo M. García, Lucas Sedeño and Agustín Ibáñez.

in Brain

November 2016; p ublished online September 2016 .

Journal Article. Subjects: Neuropathology; Disorders of the Nervous System. 12478 words.

Recursive social decision-making requires the use of flexible, context-sensitive long-term strategies for negotiation. To succeed in social bargaining, participants’ own perspectives must...

GABA transmission via ATP-dependent K+ channels regulates α-synuclein secretion in mouse striatum

Evangelia Emmanouilidou, Georgia Minakaki, Maria V. Keramioti, Mary Xylaki, Evangelos Balafas, Margarita Chrysanthou-Piterou, Ismini Kloukina and Kostas Vekrellis.

in Brain

March 2016; p ublished online February 2016 .

Journal Article. Subjects: Neuropathology; Disorders of the Nervous System. 11787 words.

α-Synuclein is readily released in human and mouse brain parenchyma, even though the normal function of the secreted protein has not been yet elucidated. Under pathological conditions, such...

Existing Pittsburgh Compound-B positron emission tomography thresholds are too high: statistical and pathological evaluation

Sylvia Villeneuve, Gil D. Rabinovici, Brendan I. Cohn-Sheehy, Cindee Madison, Nagehan Ayakta, Pia M. Ghosh, Renaud La Joie, Samia Kate Arthur-Bentil, Jacob W. Vogel, Shawn M. Marks, Manja Lehmann, Howard J. Rosen, Bruce Reed, John Olichney, Adam L. Boxer, Bruce L. Miller, Ewa Borys, Lee-Way Jin, Eric J. Huang, Lea T. Grinberg, Charles DeCarli, William W. Seeley and William Jagust.

in Brain

July 2015; p ublished online May 2015 .

Journal Article. Subjects: Neuropathology; Disorders of the Nervous System. 8441 words.

Amyloid-β, a hallmark of Alzheimer’s disease, begins accumulating up to two decades before the onset of dementia, and can be detected in vivo applying amyloid-β positron emission tomography...

The coeruleus/subcoeruleus complex in idiopathic rapid eye movement sleep behaviour disorder

Mickael Ehrminger, Alice Latimier, Nadya Pyatigorskaya, Daniel Garcia-Lorenzo, Smaranda Leu-Semenescu, Marie Vidailhet, Stéphane Lehericy and Isabelle Arnulf.

in Brain

April 2016; p ublished online February 2016 .

Journal Article. Subjects: Neuropathology; Sensory and Motor Systems; Disorders of the Nervous System. 5249 words.

See Boeve et al. (doi:10.1093/brain/aww030) for a scientific commentary on this article.

Idiopathic rapid eye movement sleep behaviour disorder is...

Scheduling Return Visits

David L. Brody.

in Concussion Care Manual

May 2019; p ublished online April 2019 .

Chapter. Subjects: Neurology; Rehabilitation Medicine; Neuropathology. 185 words.

Various concerns are taken into consideration in scheduling return visits to a concussion clinic. Some of the most commonly encountered are listed here:

Active, immediately...

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Migraine photophobia originating in cone-driven retinal pathways

Rodrigo Noseda, Carolyn A. Bernstein, Rony-Reuven Nir, Alice J. Lee, Anne B. Fulton, Suzanne M. Bertisch, Alexandra Hovaguimian, Dean M. Cestari, Rodrigo Saavedra-Walker, David Borsook, Bruce L. Doran, Catherine Buettner and Rami Burstein.

in Brain

July 2016; p ublished online May 2016 .

Journal Article. Subjects: Neuropathology; Disorders of the Nervous System; Pain Medicine. 9733 words.

Migraine headache is uniquely exacerbated by light. Using psychophysical assessments in patients with normal eyesight we found that green light exacerbates migraine headache significantly...

Fibroblast growth factor signalling in multiple sclerosis: inhibition of myelination and induction of pro-inflammatory environment by FGF9

Maren Lindner, Katja Thümmler, Ariel Arthur, Sarah Brunner, Christina Elliott, Daniel McElroy, Hema Mohan, Anna Williams, Julia M. Edgar, Cornelia Schuh, Christine Stadelmann, Susan C. Barnett, Hans Lassmann, Steve Mücklisch, Manikhandan Mudaliar, Nicole Schaeren-Wiemers, Edgar Meinl and Christopher Linington.

in Brain

July 2015; p ublished online April 2015 .

Journal Article. Subjects: Sensory and Motor Systems; Neuropathology; Disorders of the Nervous System. 10867 words.

Remyelination failure plays an important role in the pathophysiology of multiple sclerosis, but the underlying cellular and molecular mechanisms remain poorly understood. We now report...

The importance of early immunotherapy in patients with faciobrachial dystonic seizures

Julia Thompson, Mian Bi, Andrew G Murchison, Mateusz Makuch, Christian G Bien, Kon Chu, Pue Farooque, Jeffrey M Gelfand, Michael D Geschwind, Lawrence J Hirsch, Ernest Somerville, Bethan Lang, Angela Vincent, Maria I Leite, Patrick Waters and Sarosh R Irani.

in Brain

February 2018; p ublished online December 2017 .

Journal Article. Subjects: Sensory and Motor Systems; Neuropathology; Disorders of the Nervous System. 4565 words.

Abstract

Faciobrachial dystonic seizures and limbic encephalitis closely associate with antibodies to leucine-rich glioma-inactivated 1 (LGI1). Here, we...

Localizing parkinsonism based on focal brain lesions

Juho Joutsa, Andreas Horn, Joey Hsu and Michael D Fox.

in Brain

August 2018; p ublished online July 2018 .

Journal Article. Subjects: Neuropathology; Sensory and Motor Systems; Disorders of the Nervous System. 7234 words.

Abstract

Bradykinesia, rigidity, and tremor frequently co-occur, a clinical syndrome known as parkinsonism. Because this syndrome is commonly seen in...

Neuroendothelial NMDA receptors as therapeutic targets in experimental autoimmune encephalomyelitis

Richard Macrez, Maria C. Ortega, Isabelle Bardou, Anupriya Mehra, Antoine Fournier, Susanne M. A. Van der Pol, Benoit Haelewyn, Eric Maubert, Flavie Lesept, Arnaud Chevilley, Fernando de Castro, Helga E. De Vries, Denis Vivien, Diego Clemente and Fabian Docagne.

in Brain

September 2016; p ublished online July 2016 .

Journal Article. Subjects: Sensory and Motor Systems; Neuropathology; Disorders of the Nervous System. 7530 words.

Multiple sclerosis is among the most common causes of neurological disability in young adults. Here we provide the preclinical proof of concept of the benefit of a novel strategy of...

Evaluation of the noradrenergic system in Parkinson’s disease: an 11C-MeNER PET and neuromelanin MRI study

Michael Sommerauer, Tatyana D Fedorova, Allan K Hansen, Karoline Knudsen, Marit Otto, Jesper Jeppesen, Yoon Frederiksen, Jakob U Blicher, Jacob Geday, Adjmal Nahimi, Malene F Damholdt, David J Brooks and Per Borghammer.

in Brain

February 2018; p ublished online December 2017 .

Journal Article. Subjects: Neuropathology; Sensory and Motor Systems; Disorders of the Nervous System. 5638 words.

Abstract

Pathological involvement of the noradrenergic locus coeruleus occurs early in Parkinson’s disease, and widespread noradrenaline reductions are found...