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sensitive x Clinical Medicine x Clinical Pharmacology and Therapeutics x Neurology x clear all

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sensitive

Overview page. Subjects: Medicine and Health.

adj. possessing the ability to respond to a stimulus. The cells of the retina, for example, are sensitive to the stimulus of light and respond by sending nerve impulses to the...

See overview in Oxford Index

Lack of Antidepressant Effects of Low-Voltage-Sensitive T-Type Calcium Channel Blocker Ethosuximide in a Chronic Social Defeat Stress Model: Comparison with (R)-Ketamine

Zheng Tian, Chao Dong, Kai Zhang, Lijia Chang and Kenji Hashimoto.

in International Journal of Neuropsychopharmacology

P ublished online August 2018 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Neurology; Psychiatry; Neuroscience. 3298 words.

Abstract

Background

A recent study demonstrated that low-voltage-sensitive T-type calcium channel blocker...

KATP channels and migraine

Inger Jansen-Olesen and Kenneth Beri Ploug.

in Innovative drug development for headache disorders

August 2008; p ublished online May 2013 .

Chapter. Subjects: Neurology; Clinical Pharmacology and Therapeutics. 3959 words.

Chapter 19 discusses Adenosine 5´-triphosphate (ATP) sensitive K+(KATP) channels, and their relation to migraine.

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The treatment of juvenile Huntington’s disease

Martha A. Nance.

in Juvenile Huntington's Disease

January 2009; p ublished online November 2012 .

Chapter. Subjects: Neurology; Clinical Pharmacology and Therapeutics. 5565 words.

Until a medical cure for juvenile Huntington’s disease (JHD) is identified, the optimal management of a child with this condition will require a sensitive team of health professionals...

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S-Ketamine Rapidly Reverses Synaptic and Vascular Deficits of Hippocampus in Genetic Animal Model of Depression

Maryam Ardalan, Gregers Wegener, Ali H. Rafati and Jens R. Nyengaard.

in International Journal of Neuropsychopharmacology

P ublished online December 2016 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Neurology; Psychiatry; Neuroscience. 7012 words.

Abstract

Background:

The neurovascular plasticity of hippocampus is an important theory underlying major...

Fenfluramine Reduces [11C]Cimbi-36 Binding to the 5-HT2A Receptor in the Nonhuman Primate Brain

Kai-Chun Yang, Vladimir Stepanov, Stefan Martinsson, Anders Ettrup, Akihiro Takano, Gitte M Knudsen, Christer Halldin, Lars Farde and Sjoerd J Finnema.

in International Journal of Neuropsychopharmacology

P ublished online June 2017 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Neurology; Psychiatry; Neuroscience. 5922 words.

Abstract

Background

[11C]Cimbi-36 is a serotonin 2A receptor agonist positron emission tomography radioligand that...

Induction of Cannabinoid- and N-Methyl-d-Aspartate Receptor-Mediated Long-Term Depression in the Nucleus Accumbens and Dorsolateral Striatum Is Region and Age Dependent

Xiaoqun Zhang, Ze-Jun Feng and Karima Chergui.

in International Journal of Neuropsychopharmacology

P ublished online January 2015 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Neurology; Psychiatry; Neuroscience. 5585 words.

Background:

The adolescent brain is sensitive to experience-dependent plasticity and might be more vulnerable than the adult brain to the effects of some...

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Manganese-Enhanced Magnetic Resonance Imaging Reveals Differential Long-Term Neuroadaptation After Methamphetamine and the Substituted Cathinone 4-Methylmethcathinone (Mephedrone)

Bjørnar den Hollander, Mateusz Dudek, Ilkka Ojanperä, Esko Kankuri, Petri Hyytiä and Esa R Korpi.

in International Journal of Neuropsychopharmacology

April 2015; p ublished online February 2015 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Neurology; Psychiatry; Neuroscience. 7305 words.

Background:

In recent years there has been a large increase in the use of substituted cathinones such as mephedrone (4-methylmethcathinone, 4-MMC), a...

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5-HT1A Agonist Properties Contribute to a Robust Response to Vilazodone in the Novelty Suppressed Feeding Paradigm

Alvaro L. Garcia-Garcia, Míriam Navarro-Sobrino, Gila Pilosof, Pradeep Banerjee, Alex Dranovsky and E. David Leonardo.

in International Journal of Neuropsychopharmacology

P ublished online June 2016 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Neurology; Psychiatry; Neuroscience. 4190 words.

Background:

Differences in 5-HT1A receptor function have been implicated in vulnerability to depression and in response to treatment. Adding 5-HT1A partial...

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Exposure-Response Relationships during Free-Access Intravenous Alcohol Self-Administration in Nondependent Drinkers: Influence of Alcohol Expectancies and Impulsivity

Bethany L. Stangl, Vatsalya Vatsalya, Molly R. Zametkin, Megan E. Cooke, Martin H. Plawecki, Sean O’Connor and Vijay A. Ramchandani.

in International Journal of Neuropsychopharmacology

P ublished online October 2016 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Neurology; Psychiatry; Neuroscience. 6123 words.

Abstract

Background:

Self-administration is a hallmark of all addictive drugs, including alcohol. Human laboratory...

Prefrontal microRNA-221 Mediates Environmental Enrichment-Induced Increase of Locomotor Sensitivity to Nicotine

Adrian M. Gomez, Diego Altomare, Wei-Lun Sun, Narasimha M. Midde, Hao Ji, Michael Shtutman, Jill R. Turner, Kim E. Creek and Jun Zhu.

in International Journal of Neuropsychopharmacology

P ublished online August 2015 .

Journal Article. Subjects: Clinical Pharmacology and Therapeutics; Neurology; Psychiatry; Neuroscience. 8090 words.

Background:

Environmental enrichment alters susceptibility in developing drug addiction. We have demonstrated that rats raised in an enriched condition are...

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