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sensitive x Research Methods in Life Sciences x Science and Mathematics x Preclinical Medicine x clear all


Overview page. Subjects: Medicine and Health.

adj. possessing the ability to respond to a stimulus. The cells of the retina, for example, are sensitive to the stimulus of light and respond by sending nerve impulses to the...

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Engineering a high-affinity methyl-CpG-binding protein

Helle F. Jørgensen, Karen Adie, Pascal Chaubert and Adrian P. Bird.

in Nucleic Acids Research

August 2006; p ublished online August 2006 .

Journal Article. Subjects: Research Methods in Life Sciences; Proteins; Molecular Biology and Genetics. 4350 words.

Core members of the MBD protein family (MeCP2, MBD1, MBD2 and MBD4) share a methyl-CpG-binding domain that has a specific affinity for methylated CpG sites in double-stranded DNA. By...

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Real-time investigation of nucleic acids phosphorylation process using molecular beacons

Zhiwen Tang, Kemin Wang, Weihong Tan, Changbei Ma, Jun Li, Lingfeng Liu, Qiuping Guo and Xiangxian Meng.

in Nucleic Acids Research

June 2005; p ublished online June 2005 .

Journal Article. Subjects: Research Methods in Life Sciences; Enzymology; Molecular Biology and Genetics. 4199 words.

Phosphorylation of nucleic acids is an indispensable process to repair strand interruption of nucleic acids. We have studied the process of phosphorylation using molecular beacon (MB) DNA...

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A novel high-throughput activity assay for the Trypanosoma brucei editosome enzyme REL1 and other RNA ligases

Stephan Zimmermann, Laurence Hall, Sean Riley, Jesper Sørensen, Rommie E. Amaro and Achim Schnaufer.

in Nucleic Acids Research

February 2016; p ublished online September 2015 .

Journal Article. Subjects: Enzymology; Molecular Biology and Genetics; Research Methods in Life Sciences. 7890 words.

The protist parasite Trypanosoma brucei causes Human African trypanosomiasis (HAT), which threatens millions of people in sub-Saharan Africa. Without treatment the infection is almost...

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The validity of the original EuroSCORE and EuroSCORE II in patients over the age of seventy

Michael Poullis, Mark Pullan, John Chalmers and Neeraj Mediratta.

in Interactive CardioVascular and Thoracic Surgery

February 2015; p ublished online October 2014 .

Journal Article. Subjects: Molecular Biology and Genetics; Molecular and Cell Biology; Cardiovascular Medicine; Research Methods in Life Sciences. 3077 words.


EuroSCORE II, despite improving on the original EuroSCORE system, has not solved all the calibration and predictability issues. We investigated...