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Overview page. Subjects: Medicine and Health.

adj. possessing the ability to respond to a stimulus. The cells of the retina, for example, are sensitive to the stimulus of light and respond by sending nerve impulses to the...

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Engineering a high-affinity methyl-CpG-binding protein

Helle F. Jørgensen, Karen Adie, Pascal Chaubert and Adrian P. Bird.

in Nucleic Acids Research

August 2006; p ublished online August 2006 .

Journal Article. Subjects: Research Methods in Life Sciences; Proteins; Molecular Biology and Genetics. 4350 words.

Core members of the MBD protein family (MeCP2, MBD1, MBD2 and MBD4) share a methyl-CpG-binding domain that has a specific affinity for methylated CpG sites in double-stranded DNA. By...

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