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steric hindrance

Overview page. Subjects: Chemistry.

An effect in which a chemical reaction is slowed down or prevented because large groups on a reactant molecule hinder the approach of another reactant molecule.

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In vitro interactions between amphotericin B and hydrocortisone: potential implications for intrathecal therapy

Greg Hodge, Stuart H. Cohen and George R. Thompson.

in Medical Mycology

September 2015; p ublished online July 2015 .

Journal Article. Subjects: Infectious Diseases; Medical Toxicology; Environmental Science; Mycology and Fungi; Veterinary Medicine. 2315 words.

Fungal meningitis remains a severe and often lethal infection requiring aggressive antifungal therapy and in refractory cases the use of intrathecal amphotericin B (AmB). Administration of...

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