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virus

Overview page. Subjects: Computing.

Program code written to replicate by attaching copies of itself to other objects within the system, and normally also having a detrimental effect. This may range from generation of...

See overview in Oxford Index

Hepatitis E virus: a zoonosis adapting to humans

Florian Bihl and Francesco Negro.

in Journal of Antimicrobial Chemotherapy

May 2010; p ublished online March 2010 .

Journal Article. Subjects: Medical Oncology; Critical Care. 3135 words.

Hepatitis E virus (HEV) infection is gaining global attention, not only because of the increasing burden of the disease in low endemicity countries, in terms of morbidity and mortality...

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Epstein–Barr virus infections: prospects for treatment

Edward Gershburg and Joseph S. Pagano.

in Journal of Antimicrobial Chemotherapy

August 2005; p ublished online July 2005 .

Journal Article. Subjects: Medical Oncology; Critical Care. 4162 words.

Epstein–Barr virus (EBV) causes infectious mononucleosis and oral hairy leucoplakia, and is associated with a number of malignancies. There are, however, no regulatory agency-approved...

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Herpes simplex virus: the importance of asymptomatic shedding

D. M. Koelle and A. Wald.

in Journal of Antimicrobial Chemotherapy

April 2000; p ublished online April 2000 .

Journal Article. Subjects: Medical Oncology; Critical Care. 0 words.

Herpes simplex virus (HSV) is frequently shed after infection of the genital or perianal area. HSV shedding, as determined by culture, occurs on about 3% of days for immunocompetent women...

Directly acting antivirals against hepatitis C virus

Vincent Soriano, Eugenia Vispo, Eva Poveda, Pablo Labarga, Luz Martin-Carbonero, Jose Vicente Fernandez-Montero and Pablo Barreiro.

in Journal of Antimicrobial Chemotherapy

August 2011; p ublished online June 2011 .

Journal Article. Subjects: Medical Oncology; Critical Care. 9778 words.

The approval of directly acting antivirals (DAA) for the treatment of chronic hepatitis C virus (HCV) infection will represent a major breakthrough for the 180 million persons infected...

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T-cell therapy of cytomegalovirus and human immunodeficiency virus infection

S. R. Riddell and P. D. Greenberg.

in Journal of Antimicrobial Chemotherapy

April 2000; p ublished online April 2000 .

Journal Article. Subjects: Medical Oncology; Critical Care. 0 words.

Acute and persistent virus infections are limited by the development and maintenance of host T-cell responses to viral antigens. Individuals with congenital or acquired immunodeficiencies...

Hepatitis B virus escape mutants induced by antiviral therapy

Julie Sheldon and Vincent Soriano.

in Journal of Antimicrobial Chemotherapy

April 2008; p ublished online January 2008 .

Journal Article. Subjects: Medical Oncology; Critical Care. 1458 words.

The hepatitis B virus (HBV) polymerase and envelope genes overlap in such a way that resistance mutations to antiviral agents in the reverse transcriptase gene may affect the antigenicity...

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Drug discovery for human immunodeficiency virus infection: conquests and hurdles

Richard J. Whitley.

in Journal of Antimicrobial Chemotherapy

May 1996; p ublished online May 1996 .

Journal Article. Subjects: Medical Oncology; Critical Care. 0 words.

Drug development for the treatment of human immunodeficiency virus infection arena has been characterised by both successes and failures. The nucleoside reverse transcriptase inhibitors...

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Activity of penciclovir in antiviral assays against herpes simplex virus

Teresa H. Bacon, Barbara A. Howard, Lindsay C. Spender and Malcolm R. Boyd.

in Journal of Antimicrobial Chemotherapy

February 1996; p ublished online February 1996 .

Journal Article. Subjects: Medical Oncology; Critical Care. 0 words.

The effect of penciclovir and acyclovir on the replication of herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) strains was determined in MRC-5 cells infected with 0.01 pfu/cell and...

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Hepatitis B virus: old, new and future approaches to antiviral treatment

Peter Karayiannis.

in Journal of Antimicrobial Chemotherapy

April 2003; p ublished online April 2003 .

Journal Article. Subjects: Medical Oncology; Critical Care. 20580 words.

Patients chronically infected with hepatitis B virus (HBV) run the risk of developing cirrhosis and hepatocellular carcinoma in later life. Antiviral treatment offers the only means of...

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The many challenges of facial herpes simplex virus infection

Jørgen Esmann.

in Journal of Antimicrobial Chemotherapy

February 2001; p ublished online February 2001 .

Journal Article. Subjects: Medical Oncology; Critical Care. 0 words.

Infection with herpes simplex virus type 1 (HSV-1) is common throughout the world, with many cases leading to symptomatic facial herpes. Following primary infection, HSV-1 establishes...

Mutations conferring zanamivir resistance in human influenza virus N2 neuraminidases compromise virus fitness and are not stably maintained in vitro

Thomas Zürcher, Phillip J. Yates, Janet Daly, Anjali Sahasrabudhe, Matthew Walters, Laura Dash, Margaret Tisdale and Jennifer L. McKimm-Breschkin.

in Journal of Antimicrobial Chemotherapy

October 2006; p ublished online August 2006 .

Journal Article. Subjects: Medical Oncology; Critical Care. 7105 words.

Background: Viruses resistant to zanamivir have been generated in vitro, but no resistant virus has yet been isolated from a zanamivir-treated immunocompetent patient. In...

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Genotypic resistance to lamivudine among hepatitis B virus isolates in Mexico

Cosme Alvarado-Esquivel, Manuela de la Ascensión Carrera-Gracia, Carlos Jesús Conde-González, Luis Juárez-Figueroa, Lilia Ruiz-Maya, Sergio Aguilar-Benavides, Alejandro Torres-Valenzuela and Erwin Sablon.

in Journal of Antimicrobial Chemotherapy

February 2006; p ublished online December 2005 .

Journal Article. Subjects: Medical Oncology; Critical Care. 2154 words.

Background: Drug resistance of hepatitis B virus (HBV) is an increasing clinical problem. Resistance to lamivudine in HBV isolates in Mexico has been poorly explored.

null...

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Erythrocyte-mediated delivery of a new homodinucleotide active against human immunodeficiency virus and herpes simplex virus

Luigia Rossi, Sonja Serafini, Loredana Cappellacci, Emanuela Balestra, Giorgio Brandi, Giuditta F. Schiavano, Palmarisa Franchetti, Mario Grifantini, Carlo-Federico Perno and Mauro Magnani.

in Journal of Antimicrobial Chemotherapy

June 2001; p ublished online June 2001 .

Journal Article. Subjects: Medical Oncology; Critical Care. 6024 words.

Monocyte-derived macrophages (MDMs) play a central role in the pathogenesis of infection by human immunodeficiency virus (HIV-1) and represent one of the main reservoirs of the virus in the...

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Inhibition of respiratory syncytial virus by RhoA-derived peptides: implications for the development of improved antiviral agents targeting heparin-binding viruses

Philip J. Budge and Barney S. Graham.

in Journal of Antimicrobial Chemotherapy

August 2004; p ublished online August 2004 .

Journal Article. Subjects: Medical Oncology; Critical Care. 3135 words.

The respiratory syncytial virus (RSV) fusion glycoprotein (F) can interact with the small intracellular GTPase RhoA, and peptides derived from RhoA inhibit RSV replication. These...

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Progression of liver fibrosis in patients coinfected with hepatitis C virus and human immunodeficiency virus undergoing antiretroviral therapy

Juan A. Pineda and Juan Macías.

in Journal of Antimicrobial Chemotherapy

April 2005; p ublished online April 2005 .

Journal Article. Subjects: Medical Oncology; Critical Care. 2381 words.

As the immunosuppression caused by human immunodeficiency virus (HIV) accelerates the progression of hepatitis C virus (HCV)-related liver fibrosis, the immune reconstitution associated with...

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ASP2151, a novel helicase–primase inhibitor, possesses antiviral activity against varicella–zoster virus and herpes simplex virus types 1 and 2

Koji Chono, Kiyomitsu Katsumata, Toru Kontani, Masayuki Kobayashi, Kenji Sudo, Tomoyuki Yokota, Kenji Konno, Yasuaki Shimizu and Hiroshi Suzuki.

in Journal of Antimicrobial Chemotherapy

August 2010; p ublished online June 2010 .

Journal Article. Subjects: Medical Oncology; Critical Care. 5914 words.

Objectives

To evaluate and describe the anti-herpesvirus effect of ASP2151, amenamevir, a novel non-nucleoside oxadiazolylphenyl-containing herpesvirus...

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Response to raltegravir-based salvage therapy in HIV-infected patients with hepatitis C virus or hepatitis B virus coinfection

Liliana Elena Weimer, Vincenzo Fragola, Marco Floridia, Giovanni Guaraldi, Nicoletta Ladisa, Daniela Francisci, Rita Bellagamba, Anna Degli Antoni, Giustino Parruti, Andrea Giacometti, Paolo Emilio Manconi, Angela Vivarelli, Gabriella D'Ettorre, Maria Stella Mura, Stefania Cicalini, Roberta Preziosi, Laura Sighinolfi, Gabriella Verucchi, Raffaella Libertone, Marcello Tavio, Loredana Sarmati and Raffaella Bucciardini.

in Journal of Antimicrobial Chemotherapy

January 2013; p ublished online September 2012 .

Journal Article. Subjects: Medical Oncology; Critical Care. 3191 words.

Objectives

To define the impact of coinfection with hepatitis B virus (HBV) or hepatitis C virus (HCV) on viroimmunological response to raltegravir-based...

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Putranjivain A from Euphorbia jolkini inhibits both virus entry and late stage replication of herpes simplex virus type 2 in vitro

Hua-Yew Cheng, Ta-Chen Lin, Chien-Min Yang, Kuo-Chih Wang, Liang-Tzung Lin and Chun-Ching Lin.

in Journal of Antimicrobial Chemotherapy

April 2004; p ublished online April 2004 .

Journal Article. Subjects: Medical Oncology; Critical Care. 5038 words.

Aims: To investigate the in vitro antiviral properties of putranjivain A, isolated from the whole plant of Euphorbia jolkini Bioss (Euphorbiaceae).

Methods...

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Characterization of recombinant influenza B viruses with key neuraminidase inhibitor resistance mutations

David Jackson, Wendy Barclay and Thomas Zürcher.

in Journal of Antimicrobial Chemotherapy

February 2005; p ublished online February 2005 .

Journal Article. Subjects: Medical Oncology; Critical Care. 6338 words.

Objectives and methods: An influenza B virus plasmid-based rescue system was used to introduce site-specific mutations, previously observed in neuraminidase (NA)...

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Strain-specific antiviral activity of iminosugars against human influenza A viruses

S. Hussain, J. L. Miller, D. J. Harvey, Y. Gu, P. B. Rosenthal, N. Zitzmann and J. W. McCauley.

in Journal of Antimicrobial Chemotherapy

January 2015; p ublished online September 2014 .

Journal Article. Subjects: Medical Oncology; Critical Care. 10920 words.

Objectives

Drugs that target host cell processes can be employed to complement drugs that specifically target viruses, and iminosugar compounds that inhibit...

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