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renin-angiotensin system

Overview page. Subjects: Chemistry.

A system involved in the control of blood pressure. Renin, secreted into the blood by the kidney in response to osmotic changes, anoxia, or kidney trauma, acts on angiotensinogen to ...

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Renin–angiotensin system and neprilysin

João Pedro Ferreira and Patrick Rossignol.

in The ESC Textbook of Cardiovascular Medicine

December 2018; p ublished online July 2018 .

Chapter. Subjects: Cardiovascular Medicine. 5697 words.

The advent of drugs able to modulate the renin–angiotensin system (RAS), and more recently the neprilysin inhibitor sacubitril in combination with a RAS blocker, has improved the outcome of...

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Tissue renin-angiotensin systems and reproduction.

G P Vinson, E Saridogan, J R Puddefoot and O Djahanbakhch.

in Human Reproduction

April 1997; p ublished online April 1997 .

Journal Article. Subjects: Reproductive Medicine. 0 words.

The continued acquisition of information on the distribution of expression of components of the renin-angiotensin system shows that it has functions in the tissues that are quite unrelated...

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Blockade of the renin–angiotensin–aldosterone system

Steven M. Shaw, John E. Macdonald and Simon G. Williams.

in Chronic Heart Failure

October 2008; p ublished online May 2011 .

Chapter. Subjects: Cardiovascular Medicine. 2092 words.

Blockade of the renin–angiotensin–aldosterone system is a cornerstone of treatment of patients with chronic heart failure (CHF).

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The renin–angiotensin system and malignancy

Eleanor I. Ager, Jaclyn Neo and Christopher Christophi.

in Carcinogenesis

September 2008; p ublished online July 2008 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics. 7681 words.

The renin–angiotensin system (RAS) is usually associated with its systemic action on cardiovascular homoeostasis. However, recent studies suggest that at a local tissue level, the RAS...

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Renin angiotensin system and gender differences in the cardiovascular system

Marcus Fischer, Andrea Baessler and Heribert Schunkert.

in Cardiovascular Research

February 2002; p ublished online February 2002 .

Journal Article. Subjects: Cardiovascular Medicine. 4055 words.

Abstract

In the effort to explain gender-related differences of the cardiovascular system, the renin–angiotensin system experienced intensive exploration....

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Is there a local renin—angiotensin system in the heart?

A.H.Jan Danser, Jasper J Saris, Martin P Schuijt and Jorge P van Kats.

in Cardiovascular Research

November 1999; p ublished online November 1999 .

Journal Article. Subjects: Cardiovascular Medicine. 10215 words.

Abstract

The existence of a local renin—angiotensin system in the heart is still a controversial issue. This review discusses the evidence, obtained from...

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Molecular regulation of the renin–angiotensin system in haemodialysis patients

Johannes J. Kovarik, Marlies Antlanger, Oliver Domenig, Christopher C. Kaltenecker, Manfred Hecking, Michael Haidinger, Johannes Werzowa, Chantal Kopecky and Marcus D. Säemann.

in Nephrology Dialysis Transplantation

January 2015; p ublished online August 2014 .

Journal Article. Subjects: Nephrology. 4579 words.

Background

Blockade of the renin–angiotensin system (RAS) exerts beneficial effects in patients with mild-to-moderate chronic kidney disease, yet evidence...

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Interactions between endothelin-1 and the renin–angiotensin–aldosterone system

Gian Paolo Rossi, Alfredo Sacchetto, Maurizio Cesari and Achille C Pessina.

in Cardiovascular Research

August 1999; p ublished online August 1999 .

Journal Article. Subjects: Cardiovascular Medicine. 4953 words.

Abstract

The renin–angiotensin–aldosterone (RAA) system and the endothelin (ET) system entail the most potent vasopressor mechanisms identified to date....

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Estrogen, natriuretic peptides and the renin–angiotensin system<sup>1</sup>

Mercedes L Kuroski de Bold.

in Cardiovascular Research

March 1999; p ublished online March 1999 .

Journal Article. Subjects: Cardiovascular Medicine. 6268 words.

Abstract

There are significant gender-specific differences in the incidence of hypertension and the clinical outcome of cardiovascular disease between...

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The renin–angiotensin system and experimental heart failure

Kai C Wollert and Helmut Drexler.

in Cardiovascular Research

September 1999; p ublished online September 1999 .

Journal Article. Subjects: Cardiovascular Medicine. 10151 words.

Abstract

Experimental studies suggest that the renin–angiotensin system (RAS) and its primary effector peptide, angiotensin II (Ang II), are involved in the...

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Cardiorenal protection during chronic renin–angiotensin–aldosterone system suppression: evidences and caveats

Gema Ruiz-Hurtado and Luis Miguel Ruilope.

in European Heart Journal - Cardiovascular Pharmacotherapy

April 2015; p ublished online March 2015 .

Journal Article. 3393 words.

Blocking the renin–angiotensin–aldosterone system (RAAS) has widely shown to be good for the protection of both cardiovascular and renal systems. A large number of trials have demonstrated...

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Variants of renin–angiotensin system genes and echocardiographic left ventricular mass

H Kauma, M Ikäheimo, M.J Savolainen, T.-R Kiema, A.O Rantala, M Lilja, A Reunanen and Y.A Kesäniemi.

in European Heart Journal

July 1998; p ublished online July 1998 .

Journal Article. Subjects: Cardiovascular Medicine. 17 words.

Aims

Variants of renin–angiotensin system genes are shown to be associated with cardiovascular pathology. The association between renin–angiotensin system genes...

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Tetralogy of Fallot repair results in activation of the renin-angiotensin-aldosterone system

R. D. Mainwaring, J. J. Lamberti, J. W. Moore, G. F. Billman, T. L. Carter and J. c. Nelson.

in European Heart Journal

September 1996 .

Journal Article. Subjects: Cardiovascular Medicine. 0 words.

Fluid retention is a common problem following transannular patch repair of tetralogy of Fallot. The present study was undertaken to evaluate whether humoral substances may contribute to...

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Polymorphism of renin–angiotensin system genes in dialysis patients—association with cerebrovascular disease

Attilio Losito, Kamini Kalidas, Stefania Santoni, Luigi Ceccarelli and Steve Jeffery.

in Nephrology Dialysis Transplantation

December 2002; p ublished online December 2002 .

Journal Article. Subjects: Nephrology. 3536 words.

Background. Polymorphisms of genes of the renin–angiotensin system (RAS) have been found in association with cerebrovascular and cardiovascular diseases in the general...

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Renin–Angiotensin System Genetic Polymorphisms and Brain White Matter Lesions in Older Australians

Amelia A. Assareh, Karen A. Mather, John D. Crawford, Wei Wen, Kaarin J. Anstey, Simon Easteal, Xiaoyun Tan, Holly A. Mack, John B.J. Kwok, Peter R. Schofield and Perminder S. Sachdev.

in American Journal of Hypertension

September 2014; p ublished online March 2014 .

Journal Article. Subjects: Cardiovascular Medicine; Biological Sciences. 5036 words.

BACKGROUND

White matter lesions (WMLs), seen as hyperintensities on T2-weighted magnetic resonance imaging brain scans, are common in the brains of healthy...

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Blockade of the renin–angiotensin system increases graft survival in patients with chronic allograft nephropathy

Marika A. Artz, Luuk B. Hilbrands, George Borm, Karel J. M. Assmann and Jack F. M. Wetzels.

in Nephrology Dialysis Transplantation

November 2004; p ublished online October 2004 .

Journal Article. Subjects: Nephrology. 4087 words.

Background. Chronic allograft nephropathy (CAN) is the leading cause of late allograft failure, with only limited treatment options. Blockade of the renin–angiotensin system...

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Genetic polymorphisms of the renin-angiotensin system in end-stage renal disease

Monika Buraczynska, Piotr Ksiazek, Andrzej Drop, Wojciech Zaluska, Danuta Spasiewicz and Andrzej Ksiazek.

in Nephrology Dialysis Transplantation

April 2006; p ublished online December 2005 .

Journal Article. Subjects: Nephrology. 3511 words.

Background. End-stage renal disease (ESRD) is a complex phenotype resulting from underlying kidney diseases of different etiologies as well as from environmental and genetic...

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Critical role for p47<sup> <i>phox</i> </sup> in renin–angiotensin system activation and blood pressure regulation

Karsten Grote, Magdalene Ortmann, Gustavo Salguero, Carola Doerries, Ulf Landmesser, Maren Luchtefeld, Ralf P. Brandes, Wilfried Gwinner, Thomas Tschernig, Ernst-Georg Brabant, Andreas Klos, Arnd Schaefer, Helmut Drexler and Bernhard Schieffer.

in Cardiovascular Research

August 2006; p ublished online August 2006 .

Journal Article. Subjects: Cardiovascular Medicine. 5723 words.

Abstract

Objective: Renin–angiotensin system (RAS) activation leads to increased production of NAD(P)H oxidase-derived reactive oxygen species...

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Which patients should be on renin–angiotensin system blockers after coronary surgery?

Aiman Alassar, Samer Bazerbashi, Rachel Easto and Jonathan Unsworth-White.

in Interactive CardioVascular and Thoracic Surgery

October 2014; p ublished online July 2014 .

Journal Article. Subjects: Molecular Biology and Genetics; Molecular and Cell Biology. 3063 words.

A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was ‘which patients should be on renin-angiotensin system blockers after...

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Cardiac repolarization during hypoglycaemia and hypoxaemia in healthy males: impact of renin–angiotensin system activity

Rikke Due-Andersen, Thomas Høi-Hansen, Niels Vidiendal Olsen, Charlotte Ellen Larroude, Jørgen Kim Kanters, Frans Boomsma, Ulrik Pedersen-Bjergaard and Birger Thorsteinsson.

in EP Europace

February 2008; p ublished online January 2008 .

Journal Article. Subjects: Cardiovascular Medicine. 5161 words.

Aims

Activity in the renin–angiotensin system (RAS) may influence the susceptibility to cardiac arrhythmia. To study the effect of basal RAS activity on...

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