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saltatory conduction

Overview page. Subjects: Medicine and Health.

The means by which a nerve impulse is conducted rapidly through myelinated fibres. The wave of depolarization appears to leap from one node of Ranvier to the next.

See overview in Oxford Index

saltatory conduction

Overview page. Subjects: Medicine and Health.

The means by which a nerve impulse is conducted rapidly through myelinated fibres. The wave of depolarization appears to leap from one node of Ranvier to the next.

See overview in Oxford Index

saltatory conduction

Edited by Richard Cammack, Teresa Atwood, Peter Campbell, Howard Parish, Anthony Smith, Frank Vella and John Stirling.

in Oxford Dictionary of Biochemistry and Molecular Biology

January 2006; p ublished online January 2008 .

Reference Entry. Subjects: Biochemistry. 22 words.

the passage of a nerve impulse across a gap, as between the nodes of Ranvier in a myelinated nerve fibre.

saltatory conduction

Michael Kent.

in The Oxford Dictionary of Sports Science & Medicine

January 2006; p ublished online January 2007 .

Reference Entry. Subjects: Sports and Exercise Medicine. 30 words.

The means by which a nerve impulse is conducted rapidly through myelinated fibres. The wave of depolarization appears to leap from one ...

The physiological effect of anti-GM1 antibodies on saltatory conduction and transmembrane currents in single motor axons.

N Hirota, R Kaji, H Bostock, K Shindo, T Kawasaki, K Mizutani, N Oka, N Kohara, T Saida and J Kimura.

in Brain

December 1997; p ublished online December 1997 .

Journal Article. Subjects: Neurology; Neuroscience. 0 words.

Anti-ganglioside (anti-GM1) antibodies have been implicated in the pathogenesis of Guillain-Barré syndrome, multifocal motor neuropathy and motor neuron diseases. It has been held that they...

Myelin Function and Saltatory Conduction

Stephen G. Waxman and Lakshmi Bangalore.

in Neuroglia

October 2004; p ublished online September 2013 .

Chapter. Subjects: Neuroscience. 9264 words.

The need for rapid conduction of the nerve impulse serves as a driving force that can determine and increase animal size. For an axon without myelin, the speed of impulse ...

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nodes of Ranvier

Michael Kent.

in The Oxford Dictionary of Sports Science & Medicine

January 2006; p ublished online January 2007 .

Reference Entry. Subjects: Sports and Exercise Medicine. 34 words.

Regularly spaced constrictions of the myelin sheath on medullated nerve fibres. The nodes allow saltatory conduction to take place. A ...

node of Ranvier

John Lackie.

in A Dictionary of Biomedicine

January 2010; p ublished online January 2010 .

Reference Entry. Subjects: Clinical Medicine. 35 words.

A nonmyelinated region of neuronal plasma membrane in a myelinated axon. They are the sites where action potentials are propagated by saltatory conduction and have high concentrations of ...

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CASPRs

John Lackie.

in A Dictionary of Biomedicine

January 2010; p ublished online January 2010 .

Reference Entry. Subjects: Clinical Medicine. 54 words.

Members of the *neurexin family of transmembrane adhesion/signalling proteins, that may have a role in the forming the functionally distinct domains critical for saltatory conduction in...

CASPRs

Overview page. Subjects: Medicine and Health.

Members of the neurexin family of transmembrane adhesion/signalling proteins, that may have a role in the forming the functionally distinct domains critical for saltatory conduction in...

See overview in Oxford Index

saltation

Overview page. Subjects: Psychology — Chemistry.

1 The manner in which a nerve impulse is propagated along a myelinated nerve fibre in a sequence of jumps from one node of Ranvier to the next, greatly increasing its speed of...

See overview in Oxford Index

Remyelination

James W. Fawcett, Anne E. Rosser and Stephen B. Dunnett.

in Brain Damage, Brain Repair

October 2002; p ublished online March 2012 .

Chapter. Subjects: Neuroscience. 4084 words.

Demyelination is unusual in the spectrum of pathological processes that affect the central nervous system (CNS) in that it may be followed by a spontaneous regenerative process. This...

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Degeneration and Regeneration of Myelin in the Central Nervous System of the Aging Monkey

Alan Peters.

in From Development to Degeneration and Regeneration of the Nervous System

December 2008; p ublished online May 2009 .

Chapter. Subjects: Neuroscience. 9585 words.

Studies have been conducted on the rhesus monkey to determine what happens to the central nervous system (CNS) during normal aging. This chapter focuses one age-related change—the profound...

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Role of gap junctions in the propagation of the cardiac action potential

Stephan Rohr.

in Cardiovascular Research

May 2004; p ublished online May 2004 .

Journal Article. Subjects: Cardiovascular Medicine. 7895 words.

Abstract

Gap junctions play a pivotal role for the velocity and the safety of impulse propagation in cardiac tissue. Under physiologic conditions, the...

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Changes in the expression and localization of the paranodal protein Caspr on axons in chronic multiple sclerosis

Guus Wolswijk and Rawien Balesar.

in Brain

July 2003; p ublished online July 2003 .

Journal Article. Subjects: Neurology; Neuroscience. 7050 words.

The presence of intact paranodal junctions on myelinated axons in the CNS and PNS is crucial for both myelin sheath attachment and saltatory impulse conduction. The axonal glycoprotein...

Nodal, paranodal and juxtaparanodal axonal proteins during demyelination and remyelination in multiple sclerosis

I. Coman, M. S. Aigrot, D. Seilhean, R. Reynolds, J. A. Girault, B. Zalc and C. Lubetzki.

in Brain

P ublished online June 2006 .

Journal Article. Subjects: Neurology; Neuroscience. 5521 words.

Saltatory conduction in myelinated fibres depends on the specific molecular organization of highly specialized axonal domains at the node of Ranvier, the paranodal and the juxtaparanodal...

Genome-wide analysis of EGR2/SOX10 binding in myelinating peripheral nerve

Rajini Srinivasan, Guannan Sun, Sunduz Keles, Erin A. Jones, Sung-Wook Jang, Courtney Krueger, John J. Moran and John Svaren.

in Nucleic Acids Research

August 2012; p ublished online April 2012 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 7401 words.

Myelin is essential for the rapidity of saltatory nerve conduction, and also provides trophic support for axons to prevent axonal degeneration. Two critical determinants of myelination are...

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Abnormal sodium channel distribution in optic nerve axons in a model of inflammatory demyelination

Matthew J. Craner, Albert C. Lo, Joel A. Black and Stephen G. Waxman.

in Brain

July 2003; p ublished online July 2003 .

Journal Article. Subjects: Neurology; Neuroscience. 6107 words.

Myelinated fibres are characterized by the aggregation of Nav1.6 sodium channels within the axon membrane at nodes of Ranvier, where their presence supports saltatory conduction. In this...

Mutations in CNTNAP1 and ADCY6 are responsible for severe arthrogryposis multiplex congenita with axoglial defects

Annie Laquérriere, Jérome Maluenda, Adrien Camus, Laura Fontenas, Klaus Dieterich, Flora Nolent, Jié Zhou, Nicole Monnier, Philippe Latour, Damien Gentil, Delphine Héron, Isabelle Desguerres, Pierre Landrieu, Claire Beneteau, Benoit Delaporte, Céline Bellesme, Clarisse Baumann, Yline Capri, Alice Goldenberg, Stanislas Lyonnet, Dominique Bonneau, Brigitte Estournet, Susana Quijano-Roy, Christine Francannet, Sylvie Odent, Marie-Hélène Saint-Frison, Sabine Sigaudy, Dominique Figarella-Branger, Antoinette Gelot, Jean-Marie Mussini, Catherine Lacroix, Valerie Drouin-Garraud, Marie-Claire Malinge, Tania Attié-Bitach, Bettina Bessieres, Maryse Bonniere, Ferechte Encha-Razavi, Anne-Marie Beaufrère, Suonary Khung-Savatovsky, Marie José Perez, Alexandre Vasiljevic, Sandra Mercier, Joelle Roume, Laetitia Trestard, Pascale Saugier-Veber, Marie-Pierre Cordier, Valérie Layet, Marine Legendre, Adeline Vigouroux-Castera, Joel Lunardi, Monica Bayes, Pierre S. Jouk, Luc Rigonnot, Michèle Granier, Damien Sternberg, Josiane Warszawski, Ivo Gut, Marie Gonzales, Marcel Tawk and Judith Melki.

in Human Molecular Genetics

May 2014; p ublished online December 2013 .

Journal Article. Subjects: Genetics and Genomics. 5426 words.

Non-syndromic arthrogryposis multiplex congenita (AMC) is characterized by multiple congenital contractures resulting from reduced fetal mobility. Genetic mapping and whole exome sequencing...

Disruption of neurofascin localization reveals early changes preceding demyelination and remyelination in multiple sclerosis

O. W. Howell, A. Palser, A. Polito, S. Melrose, B. Zonta, C. Scheiermann, A. J. Vora, P. J. Brophy and R. Reynolds.

in Brain

P ublished online October 2006 .

Journal Article. Subjects: Neurology; Neuroscience. 7736 words.

Saltatory conduction in the nervous system is enabled through the intimate association between the leading edge of the myelin sheath and the axonal membrane to demarcate the node of...

Multiple sclerosis and other demyelinating diseases

Alastair Compston.

in Brain's Diseases of the Nervous System

P ublished online July 2011 .

Chapter. Subjects: Neurology. 39169 words.

The oligodendrocyte–myelin unit subserves saltatory conduction of the nerve impulse in the healthy central nervous system. At one time, many disease processes were thought exclusively to...

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