Oxford Index Search Results

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short interfering RNA

Overview page. Subjects: Biological Sciences.

Any of several types of small RNA molecules that are produced in cells from double-stranded (ds) precursors by the action of the protein Dicer. This cuts the precursor to form a...

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Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor

Torgeir Holen, Mohammed Amarzguioui, Merete T. Wiiger, Eshrat Babaie and Hans Prydz.

in Nucleic Acids Research

April 2002; p ublished online April 2002 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 7459 words.

Chemically synthesised 21–23 bp double-stranded short interfering RNAs (siRNA) can induce sequence-specific post-transcriptional gene silencing, in a process termed RNA interference (RNAi)....

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Plasma exosomes can deliver exogenous short interfering RNA to monocytes and lymphocytes

Jessica Wahlgren, Tanya De L. Karlson, Mikael Brisslert, Forugh Vaziri Sani, Esbjörn Telemo, Per Sunnerhagen and Hadi Valadi.

in Nucleic Acids Research

September 2012; p ublished online May 2012 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 6189 words.

Despite the promise of RNA interference (RNAi) and its potential, e.g. for use in cancer therapy, several technical obstacles must first be overcome. The major hurdle of RNAi-based...

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Amides are excellent mimics of phosphate internucleoside linkages and are well tolerated in short interfering RNAs

Daniel Mutisya, Chelliah Selvam, Benjamin D. Lunstad, Pradeep S. Pallan, Amanda Haas, Devin Leake, Martin Egli and Eriks Rozners.

in Nucleic Acids Research

June 2014; p ublished online May 2014 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 6684 words.

RNA interference (RNAi) has become an important tool in functional genomics and has an intriguing therapeutic potential. However, the current design of short interfering RNAs (siRNAs) is...

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short interfering RNA

Overview page. Subjects: Biological Sciences.

Any of several types of small RNA molecules that are produced in cells from double-stranded (ds) precursors by the action of the protein Dicer. This cuts the precursor to form a...

See overview in Oxford Index

short interfering RNA

Elizabeth Martin and Robert Hine.

in A Dictionary of Biology

January 2008; p ublished online January 2008 .

Reference Entry. Subjects: Biological Sciences. 153 words.

Any of several types of small RNA molecules that are produced in cells from double-stranded (ds) precursors by the action

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short interfering RNA

Edited by Robert Hine.

in A Dictionary of Biology

April 2019; p ublished online April 2019 .

Reference Entry. Subjects: Biological Sciences. 169 words.

Any of several types of small RNA molecules that are produced in cells from double-stranded (ds) precursors by the action of the protein ...

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short interfering RNA

Edited by Elizabeth Martin and Robert Hine.

in A Dictionary of Biology

June 2016; p ublished online September 2015 .

Reference Entry. Subjects: Biological Sciences. 158 words.

Any of several types of small RNA molecules that are produced in cells from double-stranded (ds) precursors by the action of the protein ...

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short interfering RNA

John Lackie.

in A Dictionary of Biomedicine

January 2010; p ublished online January 2010 .

Reference Entry. Subjects: Clinical Medicine. 5 words.

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short interfering RNA

Edited by Richard Cammack, Teresa Atwood, Peter Campbell, Howard Parish, Anthony Smith, Frank Vella and John Stirling.

in Oxford Dictionary of Biochemistry and Molecular Biology

January 2006; p ublished online January 2008 .

Reference Entry. Subjects: Biochemistry. 45 words.

abbr.: siRNA; a double‐stranded RNA, 21–23 bp long, that can specifically silence gene expression. The most efficient gene silencing

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Transiently Expressed Short Hairpin RNA Targeting 126 kDa Protein of Tobacco Mosaic Virus Interferes with Virus Infection

Ming-Min Zhao, De-Rong An, Jian Zhao, Guang-Hua Huang, Zu-Hua He and Jiang-Ye Chen.

Edited by You-Xin Jin.

in Acta Biochimica et Biophysica Sinica

January 2006; p ublished online January 2006 .

Journal Article. Subjects: Biochemistry. 0 words.

RNA interference (RNAi) silences gene expression by guiding mRNA degradation in a sequence-specific fashion. Small interfering RNA (siRNA), an intermediate of the RNAi pathway, has been...

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Specific expression of short-interfering RNA driven by human telomerase reverse transcriptase promoter in tumor cells

Xuejing Luan, Limin Guo, Zuozhen Yang, Min Liu, Xin Li and Hua Tang.

in Acta Biochimica et Biophysica Sinica

November 2008; p ublished online November 2008 .

Journal Article. Subjects: Biochemistry. 0 words.

RNA interference (RNAi) has been shown to be an effective method for inhibiting the expression of a given gene in human cells by targeting with short duplex RNA (short-interfering RNA or...

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Effects of short interfering RNA against methicillin-resistant Staphylococcus aureus coagulase in vitro and in vivo

Katsunori Yanagihara, Miwa Tashiro, Yuichi Fukuda, Hideaki Ohno, Yasuhito Higashiyama, Yoshitsugu Miyazaki, Yoichi Hirakata, Kazunori Tomono, Yohei Mizuta, Kazuhiro Tsukamoto and Shigeru Kohno.

in Journal of Antimicrobial Chemotherapy

January 2006; p ublished online December 2005 .

Journal Article. Subjects: Medical Oncology; Critical Care. 2796 words.

Objectives: The emergence of antibiotic-resistant bacteria such as Staphylococcus aureus calls for inventive research and development strategies. Inhibition of bacterial...

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The hub protein loquacious connects the microRNA and short interfering RNA pathways in mosquitoes

Mary Etna Haac, Michelle A.E. Anderson, Heather Eggleston, Kevin M. Myles and Zach N. Adelman.

in Nucleic Acids Research

April 2015; p ublished online March 2015 .

Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 8660 words.

Aedes aegypti mosquitoes vector several arboviruses of global health significance, including dengue viruses and chikungunya virus. RNA interference (RNAi) plays an important...

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siRNA

Elizabeth Martin.

in The New Oxford Dictionary for Scientific Writers and Editors

January 2009; p ublished online January 2009 .

Reference Entry. Subjects: Language Reference. 11 words.

(lower-case s, i, no space) Abbrev. for short interfering RNA.

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RISC

Overview page. Subjects: Chemistry.

abbr. for RNA‐induced silencing complex; a ribonucleoprotein complex that targets its perfectly (or partially) complementary mRNA for either cleavage or translational...

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Dicer

Overview page. Subjects: Genetics and Genomics.

A protein, originally identified as the product of the Dicer gene in Drosophila, that trims double-stranded RNA molecules to form short interfering RNAs (siRNAs) or microRNAs (miRNAs)....

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Deep sequencing of small RNAs in plants: applied bioinformatics

David J. Studholme.

in Briefings in Functional Genomics

January 2012; p ublished online December 2011 .

Journal Article. Subjects: Genetics and Genomics. 8404 words.

Small RNAs, including microRNA and short-interfering RNAs, play important roles in plants. In recent years, developments in sequencing technology have enabled the large-scale discovery of...

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Synthesis and silencing properties of siRNAs possessing lipophilic groups at their 3′-termini

Yoshihito Ueno, Koshi Kawada, Aya Shibata, Kayo Yoshikawa, Yusuke Wataya and Yukio Kitade.

in Nucleic Acids Symposium Series

September 2008; p ublished online September 2008 .

Journal Article. Subjects: Chemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 0 words.

Short interfering RNAs (siRNAs) conjugated with lipophilic groups at their 3′-termini were synthesized. The silencing activities of these siRNAs were examined by a dual-luciferase assay. It...

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The factors that contribute to the long-term expression of siRNA

Maki Shiota, Yutaka Ikeda and Renu Wadhwa.

in Nucleic Acids Symposium Series

November 2006; p ublished online November 2006 .

Journal Article. Subjects: Chemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 0 words.

RNA interference (RNAi) has become a powerful tool of knocking down a specific gene in vivo. In applications of RNAi, chemically synthesized short interfering RNAs (siRNAs) are commonly...

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The role of non-coding RNAs

John C. Lucchesi.

in Epigenetics, Nuclear Organization & Gene Function

January 2019; p ublished online March 2019 .

Chapter. Subjects: Biochemistry; Evolutionary Biology. 7276 words.

Most of the genome is transcribed into non-coding transcripts that far exceed in number the transcripts of protein-coding genes. These RNAs are subdivided into different classes. Long...

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