Journal

Cardiovascular Research

Published on behalf of The European Society of Cardiology

ISSN: 0008-6363
e-ISSN: 1755-3245 | DOI: https://dx.doi.org/10.1093/cardiovascres
Cardiovascular Research

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303A cell-Autonomous role for endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation

S Chuaiphichai, E Mcneill, G Douglas, MJ Crabtree, JK Bendall, AB Hale, NJ Alp and KM Channon.

in Cardiovascular Research

July 2014; p ublished online July 2014 .

Journal Article. Subjects: Cardiovascular Medicine. 0 words.

Nitric oxide (NO), produced by endothelial NO synthase (NOS) is a key regulator of vascular tone and blood pressure. Tetrahydrobiopterin (BH4) is an essential cofactor for endothelial NOS....

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The A10 cell line: a model for neonatal, neointimal, or differentiated vascular smooth muscle cells?

Rohini S Rao, Joseph M Miano, Eric N Olson and Charles L Seidel.

in Cardiovascular Research

October 1997; p ublished online October 1997 .

Journal Article. Subjects: Cardiovascular Medicine. 6423 words.

Abstract

Objectives: The A10 cell line was derived from the thoracic aorta of embryonic rat and is a commonly used model of vascular smooth...

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A2B or not 2B: that is the question

James M. Downey and Michael V. Cohen.

in Cardiovascular Research

November 2012; p ublished online July 2012 .

Journal Article. Subjects: Cardiovascular Medicine. 2723 words.

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A2B receptors mediate the induction of early genes and inhibition of arterial smooth muscle cell proliferation via Epac

Peter Mayer, Annette Viktoria Hinze, Anja Harst and Ivar von Kügelgen.

in Cardiovascular Research

April 2011; p ublished online November 2010 .

Journal Article. Subjects: Cardiovascular Medicine. 5235 words.

Aims

Extracellular adenosine and adenine nucleotides play important roles in the regulation of the blood vessel tonus and platelet aggregation. Less is known...

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A3 adenosine receptor stimulation modulates sarcoplasmic reticulum Ca2+ release in rat heart

Riccardo Zucchi, Gongyuan Yu, Sandra Ghelardoni, Francesca Ronca and Simonetta Ronca-Testoni.

in Cardiovascular Research

April 2001; p ublished online April 2001 .

Journal Article. Subjects: Cardiovascular Medicine. 5670 words.

Abstract

Objective: Stimulation of A3 adenosine receptors has been shown to protect cardiac myocytes from ischemic injury, but the mechanism of...

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AAV vector re-targeting: A small step on the way to cardiac-specific gene transfer

Axel Gödecke.

in Cardiovascular Research

April 2006; p ublished online April 2006 .

Journal Article. Subjects: Cardiovascular Medicine. 1632 words.

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AAV9 and Cre: a one-two punch for a quick cardiac knockout

Brent A. French and Brian H. Annex.

in Cardiovascular Research

October 2014; p ublished online September 2014 .

Journal Article. Subjects: Cardiovascular Medicine. 1300 words.

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AAV-mediated VEGF gene transfer into skeletal muscle stimulates angiogenesis and improves blood flow in a rat hindlimb ischemia model

Masahisa Shimpo, Uichi Ikeda, Yoshikazu Maeda, Masafumi Takahashi, Hiroshi Miyashita, Hiroaki Mizukami, Masashi Urabe, Akihiro Kume, Toshihiro Takizawa, Masabumi Shibuya, Keiya Ozawa and Kazuyuki Shimada.

in Cardiovascular Research

March 2002; p ublished online March 2002 .

Journal Article. Subjects: Cardiovascular Medicine. 4281 words.

Abstract

Objectives: Clinical trials on therapeutic angiogenesis using vascular endothelial growth factor (VEGF) are ongoing, however the...

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Ablation of HRC alleviates cardiac arrhythmia and improves abnormal Ca handling in CASQ2 knockout mice prone to CPVT

Bin Liu, Hsiang-Ting Ho, Lucia Brunello, Sathya D. Unudurthi, Qing Lou, Andriy E. Belevych, Lan Qian, Do Han Kim, Chunghee Cho, Paul M. L. Janssen, Thomas J. Hund, Bjorn C. Knollmann, Evangelia G. Kranias and Sándor Györke.

in Cardiovascular Research

November 2015; p ublished online September 2015 .

Journal Article. Subjects: Cardiovascular Medicine. 6521 words.

Aims

Cardiac calsequestrin (CASQ2) and histidine-rich Ca-binding protein (HRC) are sarcoplasmic reticulum (SR) Ca-binding proteins that regulate SR Ca...

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Ablation of junctin or triadin is associated with increased cardiac injury following ischaemia/reperfusion

Wen-Feng Cai, Tracy Pritchard, Stela Florea, Chi-Kueng Lam, Peidong Han, Xiaoyang Zhou, Qunying Yuan, Stephan E. Lehnart, Paul D. Allen and Evangelia G. Kranias.

in Cardiovascular Research

May 2012; p ublished online March 2012 .

Journal Article. Subjects: Cardiovascular Medicine. 5112 words.

Aims

Junctin and triadin are calsequestrin-binding proteins that regulate sarcoplasmic reticulum (SR) Ca2+ release by interacting with the ryanodine...

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Ablation of phospholamban and sarcolipin results in cardiac hypertrophy and decreased cardiac contractility

Mayilvahanan Shanmugam, Shumin Gao, Chull Hong, Nadezhda Fefelova, Martha C. Nowycky, Lai-Hua Xie, Muthu Periasamy and Gopal J. Babu.

in Cardiovascular Research

February 2011; p ublished online September 2010 .

Journal Article. Subjects: Cardiovascular Medicine. 4843 words.

Aims

Improving the sarco(endo)plasmic reticulum (SR) Ca2+-ATPase (SERCA) function has clinical implications in treating heart failure. The present study...

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Ablation therapy for atrial fibrillation (AF)

Pierre Jaïs, Rukshen Weerasooriya, Dipen C. Shah, Mélèze Hocini, Laurent Macle, Kee-Joon Choi, Christophe Scavee, Michel Haïssaguerre and Jacques Clémenty.

in Cardiovascular Research

May 2002; p ublished online May 2002 .

Journal Article. Subjects: Cardiovascular Medicine. 5940 words.

Abstract

Atrial fibrillation, the most common arrhythmia, is frequently disabling and drug resistant. Non-pharmacological approaches including surgery and...

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Abnormal Ca2+ release from cardiac sarcoplasmic reticulum in tachycardia-induced heart failure

Takeshi Yamamoto, Masafumi Yano, Michihiro Kohno, Takayuki Hisaoka, Kaoru Ono, Taketo Tanigawa, Yukio Saiki, Yuhji Hisamatsu, Tomoko Ohkusa and Masunori Matsuzaki.

in Cardiovascular Research

October 1999; p ublished online October 1999 .

Journal Article. Subjects: Cardiovascular Medicine. 6218 words.

Abstract

Objective: In heart failure, little information is available as to the Ca2+ release function of sarcoplasmic reticulum (SR), which...

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Abnormal cardiac and skeletal muscle mitochondrial function in pacing-induced cardiac failure

José Marín-García, Michael J. Goldenthal and Gordon W. Moe.

in Cardiovascular Research

October 2001; p ublished online October 2001 .

Journal Article. Subjects: Cardiovascular Medicine. 5288 words.

Abstract

Background: Previous studies have shown that marked changes in myocardial mitochondrial structure and function occur in human cardiac...

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Abnormal cardiac repolarization and impulse initiation in German shepherd dogs with inherited ventricular arrhythmias and sudden death

Eugene A Sosunov, Evgeny P Anyukhovsky, Alexei Shvilkin, Motoki Hara, Susan F Steinberg, Peter Danilo, Michael R Rosen, N Sydney Möise, Jocelyn Mérot, Vincent Probst, Flavien Charpentier, Yves Legeay and Hervé Le Marec.

in Cardiovascular Research

April 1999; p ublished online April 1999 .

Journal Article. Subjects: Cardiovascular Medicine. 8147 words.

Abstract

Objective: We tested the hypothesis that delayed afterdepolarization (DAD)-associated rhythms in German shepherd dogs with reduced...

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Abnormal conduction and repolarization in late-activated myocardium of dyssynchronously contracting hearts

David D. Spragg, Fadi G. Akar, Robert H. Helm, Richard S. Tunin, Gordon F. Tomaselli and David A. Kass.

in Cardiovascular Research

July 2005; p ublished online July 2005 .

Journal Article. Subjects: Cardiovascular Medicine. 5611 words.

Abstract

Background: Cardiac dyssynchrony due to intraventricular conduction delay produces heterogeneous regional wall stress and worsens...

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Abnormal KCNQ1 trafficking influences disease pathogenesis in hereditary long QT syndromes (LQT1)

Andrew J. Wilson, Kathryn V. Quinn, Fiona M. Graves, Maria Bitner-Glindzicz and Andrew Tinker.

in Cardiovascular Research

August 2005; p ublished online August 2005 .

Journal Article. Subjects: Cardiovascular Medicine. 5856 words.

Abstract

Objective: In the hereditary long QT syndromes the commonest defect is in the K+ channel pore forming subunit, KCNQ1. In this study we...

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Abnormal sarcoplasmic reticulum Ca2+ release in heart failure

Masafumi Yano and Takeshi Yamamoto.

in Cardiovascular Research

March 2000; p ublished online March 2000 .

Journal Article. Subjects: Cardiovascular Medicine. 905 words.

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Abnormalities in l-arginine transport and nitric oxide biosynthesis in chronic renal and heart failure

A.C. Mendes Ribeiro, T.M.C. Brunini, J.C. Ellory and G.E. Mann.

in Cardiovascular Research

March 2001; p ublished online March 2001 .

Journal Article. Subjects: Cardiovascular Medicine. 11109 words.

Abstract

Patients with chronic renal and heart failure present with hypertension and widespread vasoconstriction, respectively. Although systemic release of...

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Abnormalities in myocardial contractility, metabolism and perfusion reserve in non-stenotic coronary segments in heart failure patients

Ad F.M van den Heuvel, Jeroen J Bax, Paul K Blanksma, Willem Vaalburg, Harry J.G.M Crijns and Dirk J van Veldhuisen.

in Cardiovascular Research

July 2002; p ublished online July 2002 .

Journal Article. Subjects: Cardiovascular Medicine. 3950 words.

Abstract

Objective: Myocardial blood flow (MBF) reserve is impaired in congestive heart failure (CHF), while fluorine-18-deoxyglucose (18FDG)...

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