Ewod Droplet Microfluidic Devices Using Printed Circuit Board Fabrication

Chang‐Jin ‘CJ’ Kim and Jian Gong

in Micro/Nano Technology Systems for Biomedical Applications

Published in print March 2010 | ISBN: 9780199219698
Published online September 2010 | e-ISBN: 9780191594229 | DOI:
Ewod Droplet Microfluidic Devices Using Printed Circuit Board Fabrication

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The handling of fluids as discrete packets is a promising notion in microscale, led by droplet-based (aka digital) microfluidics operated by the electrowetting-on-dielectric (EWOD) actuation. While most current EWOD chips use a series of electrode pads in one-dimensional (1-D) lines designed for specific tasks, the desired universal chips would require user-reconfigurable paths in 2-D array. To address the high cost of fabricating multiple conductive lines necessary for such 2-D chips, the mature printed circuit board (PCB) technology has recently been exploited. Since the as-fabricated PCB surfaces require high voltages to move droplets (~500 V for water) unless a secondary fluid (e.g., oil) is used, various post-processing techniques have been developed. Four types of post-PCB microfabrication process are reported to meet the varying levels of device performances. The best showed driving voltage of ~55 V and a droplet speed of ~13 mm/s even without the use of oil.

Keywords: electrowetting; electrowetting on dielectric (EWOD); droplet microfluidics; digital microfluidics; printed circuit board fabrication; lab on a chip

Chapter.  11965 words.  Illustrated.

Subjects: Bioinformatics and Computational Biology

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