Journal Article

Pneumocystis carinii

Ann E Wakefield

in British Medical Bulletin

Volume 61, issue 1, pages 175-188
Published in print March 2002 | ISSN: 0007-1420
Published online March 2002 | e-ISSN: 1471-8391 | DOI: https://dx.doi.org/10.1093/bmb/61.1.175

      Pneumocystis carinii

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Pneumocystis carinii is an atypical fungus that causes pneumonia in immunocompromised individuals. P. carinii comprises a heterogeneous group of organisms that have been isolated from a wide range of mammalian host species. P. carinii infection is host species specific, the P. carinii organisms that infect humans have only been found in humans. This review discusses the application of molecular techniques to the study of the biology and epidemiology of P. carinii infection. It addresses the use of DNA amplification for the detection and diagnosis of P. carinii pneumonia. Studies investigating the reservoir of infectious P. carinii organisms, the routes of transmission of the infection, and the emergence of drug resistant strains of P. carinii are also discussed.

Journal Article.  6491 words. 

Subjects: Medicine and Health

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