Journal Article

A cautionary tale: High usage of topical fusidic acid and rapid clonal expansion of fusidic acid-resistant Staphylococcus aureus

Deborah A. Williamson, Stefan Monecke, Helen Heffernan, Stephen R. Ritchie, Sally A. Roberts, Arlo Upton, Mark G. Thomas and John D. Fraser

in Clinical Infectious Diseases

Published on behalf of Infectious Diseases Society of America

Published in print August 2014 | ISSN: 1058-4838
Published online August 2014 | e-ISSN: 1537-6591 | DOI: https://dx.doi.org/10.1093/cid/ciu658
A cautionary tale: High usage of topical fusidic acid and rapid clonal expansion of fusidic acid-resistant Staphylococcus aureus

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Our aim was to assess national prescribing trends and determine longitudinal resistance patterns for topical antimicrobials in New Zealand. We observed a dramatic increase in fusidic acid (FA) resistance, and clonal expansion of FA-resistant Staphylococcus aureus. This increase was concurrent with a significant national increase in topical FA dispensing.

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Subjects: Infectious Diseases ; Immunology ; Public Health and Epidemiology ; Microbiology

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