Journal Article

Fusidic acid resistance in community isolates of methicillin-susceptible <i>Staphylococcus aureus</i> and fusidic acid prescribing

Brendan W. Mason, Anthony J. Howard and John T. Magee

in Journal of Antimicrobial Chemotherapy

Published on behalf of British Society for Antimicrobial Chemotherapy

Volume 51, issue 4, pages 1033-1036
Published in print April 2003 | ISSN: 0305-7453
Published online April 2003 | e-ISSN: 1460-2091 | DOI: https://dx.doi.org/10.1093/jac/dkg190
Fusidic acid resistance in community isolates of methicillin-susceptible Staphylococcus aureus and fusidic acid prescribing

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The level of resistance to fusidic acid among community methicillin-susceptible Staphylococcus aureus (MSSA) isolates in the UK and prescriptions for fusidic acid have both doubled over the past 6 years. It is hypothesized that selective pressure arising from topical use of fusidic acid in the community accounts for this increase. A significant correlation was found between prescribing of fusidic acid and resistance at the practice level (Spearman’s rho = 0.46, 95% confidence interval 0.11–0.71, P = 0.01). Further controlled studies are required to determine whether this association is causal.

Keywords: Keywords: fusidic acid resistance, Staphylococcus aureus, fusidic acid prescribing

Journal Article.  1637 words. 

Subjects: Medical Oncology ; Critical Care

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