Chapter

Pathogenesis

Raymond W. Lam

in Depression

Second edition

Published on behalf of Oxford University Press

Published in print March 2012 | ISBN: 9780199692736
Published online February 2012 | e-ISBN: 9780191739897 | DOI: https://dx.doi.org/10.1093/med/9780199692736.003.0003

Series: Oxford Psychiatry Library

Pathogenesis

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There are likely multiple processes to explain the etiology and pathophysiology of depression, with involvement of biological, psychological and social factors.

Circadian rhythmicity, stressful life events and stress reactivity can modify genetic and biological processes (gene-environment interactions) to contribute to depression.

Endophenotypes, or genetic expressions of neural systems involved in depression, will be important in the study of the pathogenesis of depression and the development of novel treatments....

Chapter.  3063 words.  Illustrated.

Subjects: Psychiatry

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