signal recognition particle

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A complex of 7S RNA and six proteins that binds to the nascent polypeptide chain of eukaryotic proteins that have a signal sequence and halts further translation until the ribosome has become bound to rough endoplasmic reticulum. One of the SRP proteins (srp54) binds GTP and in association with 7SRNA and srp19 has GTPase activity. See Alu repeats.

http://rnp.uthct.edu/rnp/SRPDB/SRPDB.html The Signal Recognition Particle Database.

Subjects: Chemistry.

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