Journal Article

Phosphatidylethanolamine N-Methyltransferase and Regulation of Homocysteine

Cara S. Hartz and Kevin L. Schalinske

in Nutrition Reviews

Volume 64, issue 10, pages 465-467
Published in print October 2006 | ISSN: 0029-6643
Published online September 2014 | e-ISSN: 1753-4887 | DOI: https://dx.doi.org/10.1111/j.1753-4887.2006.tb00177.x
Phosphatidylethanolamine N-Methyltransferase and Regulation of Homocysteine

Show Summary Details

Preview

Homocysteine is a non-protein, sulfur-containing amino acid derived from methionine metabolism and S-adenosylmethionine (SAM)-dependent transmethylation. Elevations in plasma homocysteine have been associated with increased risk of cardiovascular disease, atherosclerosis, birth defects, Alzheimer's disease, and osteoporosis. Of the many known methyltransferases that utilize SAM, phosphatidylethanolamine N-methyltransferase has recently received much attention for its possible role in the regulation of homocysteine.

Keywords: homocysteine; phosphatidylethanolamine N-methyltransferase; phospholipid; transmethylation

Journal Article.  0 words. 

Full text: subscription required

How to subscribe Recommend to my Librarian

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content. subscribe or login to access all content.